Flights from San Francisco to Chile (SFO to CL)

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US$358

10:15am - 6:00am
Tue Sep 2nd 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Tue Sep 2nd 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Wed Sep 3rd 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 2h 58m Arrive at 11:43am in Los Angeles (LAX)

Layover in Los Angeles for 4h 32m

Wed Sep 3rd 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$358

10:15am - 6:00am
Tue Aug 19th 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Tue Aug 19th 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Wed Aug 20th 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 3h 0m Arrive at 11:45am in Los Angeles (LAX)

Layover in Los Angeles for 4h 30m

Wed Aug 20th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$371

10:15am - 6:00am
Wed Sep 3rd 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Sep 3rd 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Thu Sep 4th 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 2h 58m Arrive at 11:43am in Los Angeles (LAX)

Layover in Los Angeles for 4h 32m

Thu Sep 4th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$371

10:15am - 6:00am
Sun Aug 24th 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 24th 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Mon Aug 25th 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 3h 0m Arrive at 11:45am in Los Angeles (LAX)

Layover in Los Angeles for 4h 30m

Mon Aug 25th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$371

10:15am - 6:00am
Wed Aug 20th 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Aug 20th 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Thu Aug 21st 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 3h 0m Arrive at 11:45am in Los Angeles (LAX)

Layover in Los Angeles for 4h 30m

Thu Aug 21st 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$371

10:15am - 6:00am
Tue Aug 26th 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Tue Aug 26th 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Wed Aug 27th 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 3h 0m Arrive at 11:45am in Los Angeles (LAX)

Layover in Los Angeles for 4h 30m

Wed Aug 27th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$371

10:15am - 6:00am
Tue Aug 12th 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Tue Aug 12th 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Wed Aug 13th 2025 WestJet · WS 1696 Depart at 8:45am from Vancouver (YVR) Fly for 3h 0m Arrive at 11:45am in Los Angeles (LAX)

Layover in Los Angeles for 4h 30m

Wed Aug 13th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$373

10:15am - 6:00am
Mon Aug 11th 2025

40h 45m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Mon Aug 11th 2025 Flair Airlines · F8 1847 Depart at 10:15am from San Francisco (SFO) Fly for 2h 25m Arrive at 12:40pm in Vancouver (YVR)

Layover in Vancouver for 20h 5m

Tue Aug 12th 2025 LATAM Airlines · LA 5178 Depart at 8:45am from Vancouver (YVR) Fly for 3h 0m Arrive at 11:45am in Los Angeles (LAX)

Layover in Los Angeles for 4h 30m

Tue Aug 12th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$373

7:00am - 4:15am
Sun Aug 31st 2025

42h 15m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 31st 2025 Hawaiian Airlines · HA 6999 Depart at 7:00am from San Francisco (SFO) Fly for 5h 34m Arrive at 3:34pm in Orlando (MCO)

Layover in Orlando for 24h 51m

Mon Sep 1st 2025 Avianca · AV 219 Depart at 4:25pm from Orlando (MCO) Fly for 4h 0m Arrive at 7:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 15m

Mon Sep 1st 2025 Avianca · AV 97 Depart at 9:40pm from Bogotá (BOG) Fly for 5h 35m Arrive at 4:15am in Santiago de Chile (SCL)
US$377

7:00am - 4:15am
Wed Sep 3rd 2025

42h 15m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Sep 3rd 2025 Hawaiian Airlines · HA 6999 Depart at 7:00am from San Francisco (SFO) Fly for 5h 39m Arrive at 3:39pm in Orlando (MCO)

Layover in Orlando for 24h 46m

Thu Sep 4th 2025 Avianca · AV 219 Depart at 4:25pm from Orlando (MCO) Fly for 4h 0m Arrive at 7:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 15m

Thu Sep 4th 2025 Avianca · AV 97 Depart at 9:40pm from Bogotá (BOG) Fly for 5h 35m Arrive at 4:15am in Santiago de Chile (SCL)
US$414

1:30am - 11:04pm
Thu Sep 4th 2025

18h 34m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Sep 4th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 51m

Thu Sep 4th 2025 Copa Airlines · CM 171 Depart at 3:32pm from Panama (PTY) Fly for 6h 32m Arrive at 11:04pm in Santiago de Chile (SCL)
US$414

1:30am - 11:08pm
Mon Aug 18th 2025

18h 38m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Aug 18th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 51m

Mon Aug 18th 2025 Copa Airlines · CM 171 Depart at 3:32pm from Panama (PTY) Fly for 6h 36m Arrive at 11:08pm in Santiago de Chile (SCL)
US$418

1:30am - 7:24pm
Wed Aug 27th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Aug 27th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Wed Aug 27th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$418

1:30am - 7:24pm
Tue Aug 26th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 26th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Tue Aug 26th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Fri Aug 15th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Fri Aug 15th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Fri Aug 15th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Fri Aug 15th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Sun Aug 17th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 17th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Aug 17th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Aug 17th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Fri Aug 29th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Fri Aug 29th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Fri Aug 29th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Fri Aug 29th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Sun Aug 31st 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 31st 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Aug 31st 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Aug 31st 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Sun Aug 3rd 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 3rd 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Aug 3rd 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Aug 3rd 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Wed Aug 27th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Aug 27th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Aug 27th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Wed Aug 27th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 11:30pm
Sun Sep 7th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Sep 7th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Sep 7th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Sep 7th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 11:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Fri Aug 22nd 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Fri Aug 22nd 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Fri Aug 22nd 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Fri Aug 22nd 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Wed Aug 20th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Aug 20th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Aug 20th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Wed Aug 20th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Wed Aug 13th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Aug 13th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Aug 13th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Wed Aug 13th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Sun Aug 10th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 10th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Aug 10th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Aug 10th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Fri Aug 8th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Fri Aug 8th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Fri Aug 8th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Fri Aug 8th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Wed Aug 6th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Aug 6th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Aug 6th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Wed Aug 6th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Wed Sep 3rd 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Sep 3rd 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Sep 3rd 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Wed Sep 3rd 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Sun Aug 24th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 24th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Aug 24th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Aug 24th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Fri Sep 5th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Fri Sep 5th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Fri Sep 5th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Fri Sep 5th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$442

2:30am - 10:30pm
Wed Jul 23rd 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Jul 23rd 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Wed Jul 23rd 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Wed Jul 23rd 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$446

1:30am - 7:20pm
Tue Sep 2nd 2025

14h 50m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Sep 2nd 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Tue Sep 2nd 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 32m Arrive at 7:20pm in Santiago de Chile (SCL)
US$446

1:30am - 7:24pm
Sun Aug 24th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Aug 24th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sun Aug 24th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$446

1:30am - 7:24pm
Thu Aug 21st 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 21st 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Thu Aug 21st 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$446

1:30am - 10:44pm
Thu Aug 14th 2025

18h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 14th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Thu Aug 14th 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 36m Arrive at 10:44pm in Santiago de Chile (SCL)
US$446

1:30am - 10:44pm
Tue Aug 19th 2025

18h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 19th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Tue Aug 19th 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 36m Arrive at 10:44pm in Santiago de Chile (SCL)
US$446

1:30am - 11:08pm
Sun Aug 31st 2025

18h 38m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Aug 31st 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 51m

Sun Aug 31st 2025 Copa Airlines · CM 171 Depart at 3:32pm from Panama (PTY) Fly for 6h 36m Arrive at 11:08pm in Santiago de Chile (SCL)
US$447

1:30am - 7:20pm
Mon Sep 1st 2025

14h 50m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Sep 1st 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Mon Sep 1st 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 32m Arrive at 7:20pm in Santiago de Chile (SCL)
US$447

1:30am - 7:20pm
Thu Sep 4th 2025

14h 50m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Sep 4th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Thu Sep 4th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 32m Arrive at 7:20pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Tue Aug 5th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 5th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Tue Aug 5th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Thu Aug 14th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 14th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Thu Aug 14th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Sun Aug 31st 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Aug 31st 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sun Aug 31st 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Thu Aug 7th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 7th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Thu Aug 7th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Sun Aug 17th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Aug 17th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sun Aug 17th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Wed Aug 13th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Aug 13th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Wed Aug 13th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Wed Aug 6th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Aug 6th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Wed Aug 6th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Mon Aug 11th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Aug 11th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Mon Aug 11th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Wed Aug 20th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Aug 20th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Wed Aug 20th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Mon Aug 18th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Aug 18th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Mon Aug 18th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Tue Aug 19th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 19th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Tue Aug 19th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 7:24pm
Mon Aug 25th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Aug 25th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Mon Aug 25th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$447

1:30am - 10:40pm
Wed Sep 3rd 2025

18h 10m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Sep 3rd 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Wed Sep 3rd 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 32m Arrive at 10:40pm in Santiago de Chile (SCL)
US$447

1:30am - 10:44pm
Thu Aug 28th 2025

18h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 28th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Thu Aug 28th 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 36m Arrive at 10:44pm in Santiago de Chile (SCL)
US$450

2:30am - 10:30pm
Sun Jul 13th 2025

17h 0m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Jul 13th 2025 Avianca · AV 559 Depart at 2:30am from San Francisco (SFO) Fly for 5h 30m Arrive at 9:00am in San Salvador (SAL)

Layover in San Salvador for 1h 15m

Sun Jul 13th 2025 Avianca · AV 71 Depart at 10:15am from San Salvador (SAL) Fly for 2h 54m Arrive at 2:09pm in Bogotá (BOG)

Layover in Bogotá for 1h 21m

Sun Jul 13th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 0m Arrive at 10:30pm in Santiago de Chile (SCL)
US$452

1:30am - 10:44pm
Sat Aug 23rd 2025

18h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sat Aug 23rd 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Sat Aug 23rd 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 36m Arrive at 10:44pm in Santiago de Chile (SCL)
US$453

1:30am - 7:20pm
Sat Sep 6th 2025

14h 50m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sat Sep 6th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sat Sep 6th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 32m Arrive at 7:20pm in Santiago de Chile (SCL)
US$455

1:25am - 7:24pm
Mon Jul 14th 2025

14h 59m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Jul 14th 2025 Copa Airlines · CM 383 Depart at 1:25am from San Francisco (SFO) Fly for 7h 16m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Mon Jul 14th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$455

1:25am - 7:24pm
Sun Jul 13th 2025

14h 59m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Jul 13th 2025 Copa Airlines · CM 383 Depart at 1:25am from San Francisco (SFO) Fly for 7h 16m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sun Jul 13th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$455

1:25am - 7:24pm
Thu Jul 17th 2025

14h 59m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Jul 17th 2025 Copa Airlines · CM 383 Depart at 1:25am from San Francisco (SFO) Fly for 7h 16m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Thu Jul 17th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$455

1:25am - 10:44pm
Sun Jul 13th 2025

18h 19m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Jul 13th 2025 Copa Airlines · CM 383 Depart at 1:25am from San Francisco (SFO) Fly for 7h 16m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Sun Jul 13th 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 36m Arrive at 10:44pm in Santiago de Chile (SCL)
US$455

1:25am - 10:44pm
Wed Jul 16th 2025

18h 19m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Jul 16th 2025 Copa Airlines · CM 383 Depart at 1:25am from San Francisco (SFO) Fly for 7h 16m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 4h 27m

Wed Jul 16th 2025 Copa Airlines · CM 497 Depart at 3:08pm from Panama (PTY) Fly for 6h 36m Arrive at 10:44pm in Santiago de Chile (SCL)
US$457

12:30pm - 6:00am
Tue Aug 19th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 19th 2025 LATAM Airlines · LA 6134 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Tue Aug 19th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$457

10:55am - 6:00am
Mon Jul 21st 2025

16h 5m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Jul 21st 2025 LATAM Airlines · LA 6339 Depart at 10:55am from San Francisco (SFO) Fly for 1h 33m Arrive at 12:28pm in Los Angeles (LAX)

Layover in Los Angeles for 3h 47m

Mon Jul 21st 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$459

10:55am - 6:00am
Wed Aug 27th 2025

16h 5m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Aug 27th 2025 LATAM Airlines · LA 6214 Depart at 10:55am from San Francisco (SFO) Fly for 1h 33m Arrive at 12:28pm in Los Angeles (LAX)

Layover in Los Angeles for 3h 47m

Wed Aug 27th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$459

11:35am - 7:00am
Wed Aug 27th 2025

16h 25m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Aug 27th 2025 LATAM Airlines · LA 8983 Depart at 11:35am from San Francisco (SFO) Fly for 4h 54m Arrive at 7:29pm in Atlanta (ATL)

Layover in Atlanta for 2h 31m

Wed Aug 27th 2025 LATAM Airlines · LA 6357 Depart at 10:00pm from Atlanta (ATL) Fly for 9h 0m Arrive at 7:00am in Santiago de Chile (SCL)
US$472

9:09am - 6:00am
Tue Aug 19th 2025

17h 51m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 19th 2025 Hawaiian Airlines · HA 6995 Depart at 9:09am from San Francisco (SFO) Fly for 1h 38m Arrive at 10:47am in Los Angeles (LAX)

Layover in Los Angeles for 5h 28m

Tue Aug 19th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Tue Sep 2nd 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Sep 2nd 2025 LATAM Airlines · LA 6134 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Tue Sep 2nd 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Sat Aug 30th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sat Aug 30th 2025 LATAM Airlines · LA 6152 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Sat Aug 30th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Fri Sep 5th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Fri Sep 5th 2025 LATAM Airlines · LA 6498 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Fri Sep 5th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Mon Aug 18th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Aug 18th 2025 LATAM Airlines · LA 8940 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Mon Aug 18th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Mon Sep 1st 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Sep 1st 2025 LATAM Airlines · LA 8940 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Mon Sep 1st 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Wed Sep 3rd 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Wed Sep 3rd 2025 LATAM Airlines · LA 6293 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Wed Sep 3rd 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Mon Aug 25th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Mon Aug 25th 2025 LATAM Airlines · LA 8940 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Mon Aug 25th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Thu Sep 4th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Sep 4th 2025 LATAM Airlines · LA 6293 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Thu Sep 4th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Thu Aug 28th 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 28th 2025 LATAM Airlines · LA 6293 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Thu Aug 28th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

12:30pm - 6:00am
Thu Aug 21st 2025

14h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Aug 21st 2025 LATAM Airlines · LA 6293 Depart at 12:30pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:00pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 15m

Thu Aug 21st 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

1:30am - 7:24pm
Fri Aug 29th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Fri Aug 29th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Fri Aug 29th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$483

10:55am - 6:00am
Sun Sep 7th 2025

15h 5m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Sep 7th 2025 LATAM Airlines · LA 6178 Depart at 10:55am from San Francisco (SFO) Fly for 1h 33m Arrive at 12:28pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 47m

Sun Sep 7th 2025 LATAM Airlines · LA 603 Depart at 3:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

10:55am - 6:00am
Thu Sep 4th 2025

16h 5m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Sep 4th 2025 LATAM Airlines · LA 6339 Depart at 10:55am from San Francisco (SFO) Fly for 1h 33m Arrive at 12:28pm in Los Angeles (LAX)

Layover in Los Angeles for 3h 47m

Thu Sep 4th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$483

11:35am - 7:00am
Thu Sep 4th 2025

16h 25m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Thu Sep 4th 2025 LATAM Airlines · LA 8737 Depart at 11:35am from San Francisco (SFO) Fly for 4h 54m Arrive at 7:29pm in Atlanta (ATL)

Layover in Atlanta for 2h 26m

Thu Sep 4th 2025 LATAM Airlines · LA 6357 Depart at 9:55pm from Atlanta (ATL) Fly for 9h 5m Arrive at 7:00am in Santiago de Chile (SCL)
US$484

1:30am - 7:24pm
Fri Aug 22nd 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Fri Aug 22nd 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Fri Aug 22nd 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$484

1:30am - 7:24pm
Sat Aug 23rd 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sat Aug 23rd 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sat Aug 23rd 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$484

1:30am - 7:24pm
Fri Aug 8th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Fri Aug 8th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Fri Aug 8th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$484

1:30am - 7:24pm
Fri Aug 15th 2025

14h 54m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Fri Aug 15th 2025 Copa Airlines · CM 383 Depart at 1:30am from San Francisco (SFO) Fly for 7h 11m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Fri Aug 15th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$488

11:20am - 6:00am
Sat Aug 16th 2025

15h 40m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sat Aug 16th 2025 Frontier Airlines · F9 3308 Depart at 11:20am from San Francisco (SFO) Fly for 1h 35m Arrive at 12:55pm in Los Angeles (LAX)

Layover in Los Angeles for 3h 20m

Sat Aug 16th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$494

1:25am - 7:24pm
Sat Jul 12th 2025

14h 59m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sat Jul 12th 2025 Copa Airlines · CM 383 Depart at 1:25am from San Francisco (SFO) Fly for 7h 16m Arrive at 10:41am in Panama (PTY)

Layover in Panama for 1h 7m

Sat Jul 12th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 36m Arrive at 7:24pm in Santiago de Chile (SCL)
US$634

12:35pm - 6:00am
Sun Jul 27th 2025

14h 25m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Jul 27th 2025 LATAM Airlines · LA 6290 Depart at 12:35pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:05pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 10m

Sun Jul 27th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$646

12:35pm - 6:00am
Sun Jul 13th 2025

14h 25m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Jul 13th 2025 LATAM Airlines · LA 6290 Depart at 12:35pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:05pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 10m

Sun Jul 13th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$664

12:35pm - 6:00am
Sun Aug 3rd 2025

14h 25m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Aug 3rd 2025 LATAM Airlines · LA 6293 Depart at 12:35pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:05pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 10m

Sun Aug 3rd 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$664

12:35pm - 6:00am
Sun Jul 20th 2025

14h 25m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Jul 20th 2025 LATAM Airlines · LA 6290 Depart at 12:35pm from San Francisco (SFO) Fly for 1h 30m Arrive at 2:05pm in Los Angeles (LAX)

Layover in Los Angeles for 2h 10m

Sun Jul 20th 2025 LATAM Airlines · LA 603 Depart at 4:15pm from Los Angeles (LAX) Fly for 10h 45m Arrive at 6:00am in Santiago de Chile (SCL)
US$1112

8:10pm - 7:24am
Tue Aug 12th 2025

56h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Tue Aug 12th 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 22h 5m

Thu Aug 14th 2025 Iberia Airlines · IB 414 Depart at 2:50pm from Barcelona (BCN) Fly for 1h 25m Arrive at 4:15pm in Madrid (MAD)

Layover in Madrid for 7h 44m

Thu Aug 14th 2025 Iberia Airlines · IB 117 Depart at 11:59pm from Madrid (MAD) Fly for 13h 25m Arrive at 7:24am in Santiago de Chile (SCL)
US$1113

8:10pm - 7:24am
Tue Aug 19th 2025

32h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Tue Aug 19th 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 2h 10m

Wed Aug 20th 2025 Iberia Airlines · IB 420 Depart at 6:55pm from Barcelona (BCN) Fly for 1h 25m Arrive at 8:20pm in Madrid (MAD)

Layover in Madrid for 3h 39m

Wed Aug 20th 2025 Iberia Airlines · IB 117 Depart at 11:59pm from Madrid (MAD) Fly for 13h 25m Arrive at 7:24am in Santiago de Chile (SCL)
US$1168

7:25pm - 7:24am
Thu Aug 14th 2025

32h 59m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Thu Aug 14th 2025 Iberia Airlines · IB 2622 Depart at 7:25pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:00pm in Barcelona (BCN)

Layover in Barcelona for 2h 10m

Fri Aug 15th 2025 Iberia Airlines · IB 418 Depart at 6:10pm from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35pm in Madrid (MAD)

Layover in Madrid for 4h 24m

Fri Aug 15th 2025 Iberia Airlines · IB 117 Depart at 11:59pm from Madrid (MAD) Fly for 13h 25m Arrive at 7:24am in Santiago de Chile (SCL)
US$1225

8:10pm - 8:40am
Tue Sep 2nd 2025

33h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Sep 2nd 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 7h 20m

Thu Sep 4th 2025 Iberia Airlines · IB 2605 Depart at 12:05am from Barcelona (BCN) Fly for 14h 35m Arrive at 8:40am in Santiago de Chile (SCL)
US$1297

4:20pm - 7:50am
Wed Sep 3rd 2025

36h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Wed Sep 3rd 2025 TAP Portugal · TP 238 Depart at 4:20pm from San Francisco (SFO) Fly for 11h 10m Arrive at 11:30am in Lisbon (LIS)

Layover in Lisbon for 5h 35m

Thu Sep 4th 2025 TAP Portugal · TP 83 Depart at 5:05pm from Lisbon (LIS) Fly for 10h 5m Arrive at 11:10pm in São Paulo (GRU)

Layover in São Paulo for 5h 25m

Fri Sep 5th 2025 Turkish Airlines · TK 215 Depart at 4:35am from São Paulo (GRU) Fly for 4h 15m Arrive at 7:50am in Santiago de Chile (SCL)
US$1326

8:10pm - 8:40am
Sun Aug 17th 2025

33h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Sun Aug 17th 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 7h 20m

Tue Aug 19th 2025 Iberia Airlines · IB 2605 Depart at 12:05am from Barcelona (BCN) Fly for 14h 35m Arrive at 8:40am in Santiago de Chile (SCL)
US$1326

8:10pm - 8:40am
Tue Aug 19th 2025

33h 30m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 19th 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 7h 20m

Thu Aug 21st 2025 Iberia Airlines · IB 2605 Depart at 12:05am from Barcelona (BCN) Fly for 14h 35m Arrive at 8:40am in Santiago de Chile (SCL)
US$1336

5:45pm - 7:20am
Tue Aug 19th 2025

34h 35m
San Francisco (SFO) → Santiago de Chile (SCL)

1 Stop

Tue Aug 19th 2025 Finnair · AY 5558 Depart at 5:45pm from San Francisco (SFO) Fly for 11h 25m Arrive at 2:10pm in Madrid (MAD)

Layover in Madrid for 9h 45m

Wed Aug 20th 2025 Iberia Airlines · IB 6586 Depart at 11:55pm from Madrid (MAD) Fly for 13h 25m Arrive at 7:20am in Santiago de Chile (SCL)
US$1390

8:10pm - 8:24am
Sun Sep 7th 2025

32h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Sep 7th 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 4h 25m

Mon Sep 8th 2025 Iberia Airlines · IB 424 Depart at 9:10pm from Barcelona (BCN) Fly for 1h 25m Arrive at 10:35pm in Madrid (MAD)

Layover in Madrid for 1h 24m

Mon Sep 8th 2025 Iberia Airlines · IB 117 Depart at 11:59pm from Madrid (MAD) Fly for 13h 25m Arrive at 8:24am in Santiago de Chile (SCL)
US$1391

8:10pm - 7:24am
Sun Aug 24th 2025

32h 14m
San Francisco (SFO) → Santiago de Chile (SCL)

2 Stops

Sun Aug 24th 2025 Iberia Airlines · IB 2622 Depart at 8:10pm from San Francisco (SFO) Fly for 11h 35m Arrive at 4:45pm in Barcelona (BCN)

Layover in Barcelona for 2h 10m

Mon Aug 25th 2025 Iberia Airlines · IB 420 Depart at 6:55pm from Barcelona (BCN) Fly for 1h 25m Arrive at 8:20pm in Madrid (MAD)

Layover in Madrid for 3h 39m

Mon Aug 25th 2025 Iberia Airlines · IB 117 Depart at 11:59pm from Madrid (MAD) Fly for 13h 25m Arrive at 7:24am in Santiago de Chile (SCL)

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality.

Andy Travels

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from San Francisco to Chile (SFO to CL)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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