Flights from Panama to South Africa (PA to ZA)

Discover more affordable dates and routes for flights from Panama to South Africa (PA to ZA) within a date range.

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US$2448

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Fri Dec 12th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 1 night

Fri Dec 12th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Sat Dec 13th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2448

7:06pm - 12:35pm
Wed Dec 10th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Fri Dec 12th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 0 nights

Fri Dec 12th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Sat Dec 13th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2475

9:33pm - 12:35pm
Wed Dec 10th 2025

32h 2m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Fri Dec 12th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 759 Depart at 9:33pm from Panama (PTY) Fly for 6h 57m Arrive at 6:30am in São Paulo (GRU)

Layover in São Paulo for 16h 15m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 0 nights

Fri Dec 12th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Sat Dec 13th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2559

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Thu Dec 11th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 0 nights

Thu Dec 11th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Fri Dec 12th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2603

9:45pm - 11:50am
Wed Dec 3rd 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Sun Dec 14th 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Dec 3rd 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Dec 5th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 9 nights

Sun Dec 14th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Mon Dec 15th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$2612

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 21st 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 10 nights

Sun Dec 21st 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 22nd 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2612

7:06pm - 12:35pm
Wed Dec 10th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 21st 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 9 nights

Sun Dec 21st 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 22nd 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2619

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Tue Dec 23rd 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 12 nights

Tue Dec 23rd 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Wed Dec 24th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2619

7:06pm - 12:35pm
Wed Dec 10th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Tue Dec 23rd 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 11 nights

Tue Dec 23rd 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Wed Dec 24th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2622

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 28th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 17 nights

Sun Dec 28th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 29th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2622

7:06pm - 12:35pm
Wed Dec 10th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 28th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 16 nights

Sun Dec 28th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 29th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2623

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 14th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 3 nights

Sun Dec 14th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 15th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2623

7:06pm - 12:35pm
Wed Dec 10th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 14th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 2 nights

Sun Dec 14th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 15th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2625

7:06pm - 12:35pm
Tue Dec 9th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Thu Dec 18th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Tue Dec 9th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Wed Dec 10th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 7 nights

Thu Dec 18th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Fri Dec 19th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2625

7:06pm - 12:35pm
Wed Dec 10th 2025

34h 29m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Thu Dec 18th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 743 Depart at 7:06pm from Panama (PTY) Fly for 6h 44m Arrive at 3:50am in São Paulo (GRU)

Layover in São Paulo for 18h 55m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 6 nights

Thu Dec 18th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Fri Dec 19th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2639

9:33pm - 12:35pm
Wed Dec 10th 2025

32h 2m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 21st 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 759 Depart at 9:33pm from Panama (PTY) Fly for 6h 57m Arrive at 6:30am in São Paulo (GRU)

Layover in São Paulo for 16h 15m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 9 nights

Sun Dec 21st 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 22nd 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2646

9:33pm - 12:35pm
Wed Dec 10th 2025

32h 2m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Tue Dec 23rd 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 759 Depart at 9:33pm from Panama (PTY) Fly for 6h 57m Arrive at 6:30am in São Paulo (GRU)

Layover in São Paulo for 16h 15m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 11 nights

Tue Dec 23rd 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Wed Dec 24th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2650

9:33pm - 12:35pm
Wed Dec 10th 2025

32h 2m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 28th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 759 Depart at 9:33pm from Panama (PTY) Fly for 6h 57m Arrive at 6:30am in São Paulo (GRU)

Layover in São Paulo for 16h 15m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 16 nights

Sun Dec 28th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 29th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2651

9:33pm - 12:35pm
Wed Dec 10th 2025

32h 2m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Sun Dec 14th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 759 Depart at 9:33pm from Panama (PTY) Fly for 6h 57m Arrive at 6:30am in São Paulo (GRU)

Layover in São Paulo for 16h 15m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 2 nights

Sun Dec 14th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Mon Dec 15th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2653

9:33pm - 12:35pm
Wed Dec 10th 2025

32h 2m
Panama (PTY) → Johannesburg (JNB)

1 Stop

3:25pm - 6:30am
Thu Dec 18th 2025

22h 5m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Copa Airlines · CM 759 Depart at 9:33pm from Panama (PTY) Fly for 6h 57m Arrive at 6:30am in São Paulo (GRU)

Layover in São Paulo for 16h 15m

Thu Dec 11th 2025 LATAM Airlines · LA 8058 Depart at 10:45pm from São Paulo (GRU) Fly for 8h 50m Arrive at 12:35pm in Johannesburg (JNB)

Stay in Johannesburg for 6 nights

Thu Dec 18th 2025 LATAM Airlines · LA 8059 Depart at 3:25pm from Johannesburg (JNB) Fly for 9h 50m Arrive at 8:15pm in São Paulo (GRU)

Layover in São Paulo for 5h 15m

Fri Dec 19th 2025 Copa Airlines · CM 841 Depart at 1:30am from São Paulo (GRU) Fly for 7h 0m Arrive at 6:30am in Panama (PTY)
US$2659

7:05pm - 9:30am
Thu Nov 27th 2025

31h 25m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:45pm - 4:45pm
Wed Dec 24th 2025

28h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 45m

Fri Nov 28th 2025 Lufthansa · LH 572 Depart at 10:00pm from Frankfurt (FRA) Fly for 10h 30m Arrive at 9:30am in Johannesburg (JNB)

Stay in Johannesburg for 25 nights

Wed Dec 24th 2025 Lufthansa · LH 573 Depart at 7:45pm from Johannesburg (JNB) Fly for 10h 45m Arrive at 5:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 0m

Thu Dec 25th 2025 Condor · DE 2236 Depart at 10:30am from Frankfurt (FRA) Fly for 12h 15m Arrive at 4:45pm in Panama (PTY)
US$2725

7:05pm - 9:30am
Thu Nov 27th 2025

31h 25m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:45pm - 4:45pm
Sun Dec 7th 2025

28h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 45m

Fri Nov 28th 2025 Lufthansa · LH 572 Depart at 10:00pm from Frankfurt (FRA) Fly for 10h 30m Arrive at 9:30am in Johannesburg (JNB)

Stay in Johannesburg for 8 nights

Sun Dec 7th 2025 Lufthansa · LH 573 Depart at 7:45pm from Johannesburg (JNB) Fly for 10h 45m Arrive at 5:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 5m

Mon Dec 8th 2025 Condor · DE 2236 Depart at 10:35am from Frankfurt (FRA) Fly for 12h 10m Arrive at 4:45pm in Panama (PTY)
US$2725

7:05pm - 9:30am
Thu Nov 27th 2025

31h 25m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:45pm - 4:45pm
Wed Dec 3rd 2025

28h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 45m

Fri Nov 28th 2025 Lufthansa · LH 572 Depart at 10:00pm from Frankfurt (FRA) Fly for 10h 30m Arrive at 9:30am in Johannesburg (JNB)

Stay in Johannesburg for 4 nights

Wed Dec 3rd 2025 Lufthansa · LH 573 Depart at 7:45pm from Johannesburg (JNB) Fly for 10h 45m Arrive at 5:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 0m

Thu Dec 4th 2025 Condor · DE 2236 Depart at 10:30am from Frankfurt (FRA) Fly for 12h 15m Arrive at 4:45pm in Panama (PTY)
US$2764

7:05pm - 9:30am
Thu Nov 27th 2025

31h 25m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:45pm - 4:45pm
Wed Dec 10th 2025

28h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 45m

Fri Nov 28th 2025 Lufthansa · LH 572 Depart at 10:00pm from Frankfurt (FRA) Fly for 10h 30m Arrive at 9:30am in Johannesburg (JNB)

Stay in Johannesburg for 11 nights

Wed Dec 10th 2025 Lufthansa · LH 573 Depart at 7:45pm from Johannesburg (JNB) Fly for 10h 45m Arrive at 5:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 0m

Thu Dec 11th 2025 Condor · DE 2236 Depart at 10:30am from Frankfurt (FRA) Fly for 12h 15m Arrive at 4:45pm in Panama (PTY)
US$2771

7:05pm - 10:50am
Thu Nov 27th 2025

32h 45m
Panama (PTY) → Cape Town (CPT)

1 Stop

7:50pm - 4:45pm
Sun Dec 7th 2025

27h 55m
Cape Town (CPT) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 40m

Fri Nov 28th 2025 Condor · DE 2290 Depart at 9:55pm from Frankfurt (FRA) Fly for 11h 55m Arrive at 10:50am in Cape Town (CPT)

Stay in Cape Town for 8 nights

Sun Dec 7th 2025 Condor · DE 2291 Depart at 7:50pm from Cape Town (CPT) Fly for 12h 10m Arrive at 7:00am in Frankfurt (FRA)

Layover in Frankfurt for 3h 35m

Mon Dec 8th 2025 Condor · DE 2236 Depart at 10:35am from Frankfurt (FRA) Fly for 12h 10m Arrive at 4:45pm in Panama (PTY)
US$2838

7:05pm - 10:50am
Thu Nov 27th 2025

32h 45m
Panama (PTY) → Cape Town (CPT)

1 Stop

7:50pm - 4:45pm
Sun Dec 14th 2025

27h 55m
Cape Town (CPT) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 40m

Fri Nov 28th 2025 Condor · DE 2290 Depart at 9:55pm from Frankfurt (FRA) Fly for 11h 55m Arrive at 10:50am in Cape Town (CPT)

Stay in Cape Town for 15 nights

Sun Dec 14th 2025 Condor · DE 2291 Depart at 7:50pm from Cape Town (CPT) Fly for 12h 10m Arrive at 7:00am in Frankfurt (FRA)

Layover in Frankfurt for 3h 35m

Mon Dec 15th 2025 Condor · DE 2236 Depart at 10:35am from Frankfurt (FRA) Fly for 12h 10m Arrive at 4:45pm in Panama (PTY)
US$2852

7:05pm - 10:50am
Thu Nov 27th 2025

32h 45m
Panama (PTY) → Cape Town (CPT)

1 Stop

7:50pm - 4:45pm
Wed Dec 3rd 2025

27h 55m
Cape Town (CPT) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 40m

Fri Nov 28th 2025 Condor · DE 2290 Depart at 9:55pm from Frankfurt (FRA) Fly for 11h 55m Arrive at 10:50am in Cape Town (CPT)

Stay in Cape Town for 4 nights

Wed Dec 3rd 2025 Condor · DE 2291 Depart at 7:50pm from Cape Town (CPT) Fly for 12h 10m Arrive at 7:00am in Frankfurt (FRA)

Layover in Frankfurt for 3h 30m

Thu Dec 4th 2025 Condor · DE 2236 Depart at 10:30am from Frankfurt (FRA) Fly for 12h 15m Arrive at 4:45pm in Panama (PTY)
US$2983

7:05pm - 10:50am
Thu Nov 27th 2025

32h 45m
Panama (PTY) → Cape Town (CPT)

1 Stop

7:50pm - 4:45pm
Sun Nov 30th 2025

27h 55m
Cape Town (CPT) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 40m

Fri Nov 28th 2025 Condor · DE 2290 Depart at 9:55pm from Frankfurt (FRA) Fly for 11h 55m Arrive at 10:50am in Cape Town (CPT)

Stay in Cape Town for 1 night

Sun Nov 30th 2025 Condor · DE 2291 Depart at 7:50pm from Cape Town (CPT) Fly for 12h 10m Arrive at 7:00am in Frankfurt (FRA)

Layover in Frankfurt for 3h 35m

Mon Dec 1st 2025 Condor · DE 2236 Depart at 10:35am from Frankfurt (FRA) Fly for 12h 10m Arrive at 4:45pm in Panama (PTY)
US$3130

7:05pm - 10:50am
Thu Nov 27th 2025

32h 45m
Panama (PTY) → Cape Town (CPT)

1 Stop

7:50pm - 4:45pm
Wed Dec 17th 2025

27h 55m
Cape Town (CPT) → Panama (PTY)

1 Stop

Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)

Layover in Frankfurt for 9h 40m

Fri Nov 28th 2025 Condor · DE 2290 Depart at 9:55pm from Frankfurt (FRA) Fly for 11h 55m Arrive at 10:50am in Cape Town (CPT)

Stay in Cape Town for 18 nights

Wed Dec 17th 2025 Condor · DE 2291 Depart at 7:50pm from Cape Town (CPT) Fly for 12h 10m Arrive at 7:00am in Frankfurt (FRA)

Layover in Frankfurt for 3h 30m

Thu Dec 18th 2025 Condor · DE 2236 Depart at 10:30am from Frankfurt (FRA) Fly for 12h 15m Arrive at 4:45pm in Panama (PTY)
US$3279

9:45pm - 11:50am
Sat Dec 6th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Fri Dec 12th 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 8th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 4 nights

Fri Dec 12th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Sat Dec 13th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$3364

9:45pm - 10:50am
Sat Dec 6th 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:05pm - 7:50pm
Fri Dec 12th 2025

31h 45m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Mon Dec 8th 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 4 nights

Fri Dec 12th 2025 Turkish Airlines · TK 43 Depart at 7:05pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:00am in Istanbul (IST)

Layover in Istanbul for 7h 50m

Sat Dec 13th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$3404

9:45pm - 10:50am
Wed Dec 3rd 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:05pm - 7:50pm
Sun Dec 14th 2025

31h 45m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 3rd 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Fri Dec 5th 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 9 nights

Sun Dec 14th 2025 Turkish Airlines · TK 43 Depart at 7:05pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:00am in Istanbul (IST)

Layover in Istanbul for 7h 50m

Mon Dec 15th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$3494

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Fri Dec 12th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 9 nights

Fri Dec 12th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sat Dec 13th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3501

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Fri Dec 26th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 23 nights

Fri Dec 26th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sat Dec 27th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3503

9:45pm - 11:50am
Sat Nov 29th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Tue Dec 9th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 1st 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 8 nights

Tue Dec 9th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Wed Dec 10th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3505

9:45pm - 11:50am
Sat Nov 29th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Mon Dec 15th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 1st 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 14 nights

Mon Dec 15th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Tue Dec 16th 2025 Turkish Airlines · TK 900 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3506

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Tue Dec 9th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 6 nights

Tue Dec 9th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Wed Dec 10th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3524

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Wed Dec 10th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 7 nights

Wed Dec 10th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Thu Dec 11th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3527

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Wed Dec 17th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 14 nights

Wed Dec 17th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Thu Dec 18th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3527

9:45pm - 11:50am
Sat Nov 29th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Wed Dec 10th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 1st 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 9 nights

Wed Dec 10th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Thu Dec 11th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3532

9:45pm - 11:50am
Sat Nov 29th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Mon Dec 8th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 1st 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 7 nights

Mon Dec 8th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Tue Dec 9th 2025 Turkish Airlines · TK 900 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3533

9:45pm - 11:50am
Sat Nov 29th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Thu Dec 11th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 1st 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 10 nights

Thu Dec 11th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Fri Dec 12th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3534

9:45pm - 11:50am
Wed Nov 26th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Wed Dec 10th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Nov 26th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Nov 28th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 12 nights

Wed Dec 10th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Thu Dec 11th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3535

9:45pm - 11:50am
Wed Nov 26th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Mon Dec 8th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Nov 26th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Nov 28th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 10 nights

Mon Dec 8th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Tue Dec 9th 2025 Turkish Airlines · TK 900 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3537

9:45pm - 11:50am
Wed Dec 3rd 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sat Dec 13th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Dec 3rd 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Dec 5th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 8 nights

Sat Dec 13th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sun Dec 14th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3548

9:45pm - 11:50am
Wed Nov 26th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sat Dec 13th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Nov 26th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Nov 28th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 15 nights

Sat Dec 13th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sun Dec 14th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3561

9:45pm - 11:50am
Wed Dec 3rd 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sat Dec 20th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Dec 3rd 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Dec 5th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 15 nights

Sat Dec 20th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sun Dec 21st 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3563

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sun Dec 7th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 4 nights

Sun Dec 7th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Mon Dec 8th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3566

9:45pm - 11:50am
Sat Nov 29th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sun Dec 7th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 1st 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 6 nights

Sun Dec 7th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Mon Dec 8th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3626

9:45pm - 11:50am
Sat Dec 6th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Mon Dec 15th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 8th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 7 nights

Mon Dec 15th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Tue Dec 16th 2025 Turkish Airlines · TK 900 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3644

9:45pm - 10:50am
Mon Dec 1st 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:10pm - 7:50pm
Tue Dec 9th 2025

31h 40m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Wed Dec 3rd 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 6 nights

Tue Dec 9th 2025 Turkish Airlines · TK 39 Depart at 7:10pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:05am in Istanbul (IST)

Layover in Istanbul for 7h 45m

Wed Dec 10th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$3658

9:45pm - 11:50am
Sat Dec 6th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Thu Dec 25th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 8th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 17 nights

Thu Dec 25th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Fri Dec 26th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3669

9:45pm - 10:50am
Sat Nov 29th 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:05pm - 5:05pm
Wed Dec 10th 2025

29h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Mon Dec 1st 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 9 nights

Wed Dec 10th 2025 Turkish Airlines · TK 43 Depart at 7:05pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:00am in Istanbul (IST)

Layover in Istanbul for 2h 0m

Thu Dec 11th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3719

9:45pm - 11:50am
Wed Nov 26th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sun Nov 30th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Nov 26th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Nov 28th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 2 nights

Sun Nov 30th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Mon Dec 1st 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3732

9:45pm - 10:50am
Sat Dec 6th 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:05pm - 5:05pm
Sun Dec 28th 2025

29h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Mon Dec 8th 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 20 nights

Sun Dec 28th 2025 Turkish Airlines · TK 43 Depart at 7:05pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:00am in Istanbul (IST)

Layover in Istanbul for 2h 0m

Mon Dec 29th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3796

9:45pm - 11:50am
Mon Dec 8th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Wed Dec 17th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 8th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 10th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 7 nights

Wed Dec 17th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Thu Dec 18th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3816

9:45pm - 11:50am
Mon Dec 8th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Sun Dec 14th 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 8th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 10th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 4 nights

Sun Dec 14th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Mon Dec 15th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$3866

9:45pm - 10:50am
Sat Dec 6th 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:05pm - 5:05pm
Mon Dec 8th 2025

29h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Mon Dec 8th 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 0 nights

Mon Dec 8th 2025 Turkish Airlines · TK 43 Depart at 7:05pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:00am in Istanbul (IST)

Layover in Istanbul for 2h 0m

Tue Dec 9th 2025 Turkish Airlines · TK 900 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$3926

9:45pm - 11:50am
Mon Dec 22nd 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Fri Dec 26th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 22nd 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 24th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 2 nights

Fri Dec 26th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sat Dec 27th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4034

9:45pm - 10:50am
Wed Dec 17th 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:10pm - 7:50pm
Tue Dec 23rd 2025

31h 40m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Wed Dec 17th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Fri Dec 19th 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 4 nights

Tue Dec 23rd 2025 Turkish Airlines · TK 39 Depart at 7:10pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:05am in Istanbul (IST)

Layover in Istanbul for 7h 45m

Wed Dec 24th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$4038

9:45pm - 10:50am
Mon Dec 8th 2025

30h 5m
Panama (PTY) → Johannesburg (JNB)

1 Stop

7:05pm - 5:05pm
Fri Dec 26th 2025

29h 0m
Johannesburg (JNB) → Panama (PTY)

1 Stop

Mon Dec 8th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 30m

Wed Dec 10th 2025 Turkish Airlines · TK 42 Depart at 2:05am from Istanbul (IST) Fly for 9h 45m Arrive at 10:50am in Johannesburg (JNB)

Stay in Johannesburg for 16 nights

Fri Dec 26th 2025 Turkish Airlines · TK 43 Depart at 7:05pm from Johannesburg (JNB) Fly for 9h 55m Arrive at 6:00am in Istanbul (IST)

Layover in Istanbul for 2h 0m

Sat Dec 27th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4104

9:45pm - 11:50am
Sat Dec 13th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Mon Dec 22nd 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 13th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 15th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 7 nights

Mon Dec 22nd 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Tue Dec 23rd 2025 Turkish Airlines · TK 900 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4127

9:45pm - 11:50am
Sat Dec 13th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Fri Dec 26th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 13th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 15th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 11 nights

Fri Dec 26th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sat Dec 27th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4153

9:45pm - 11:50am
Sat Dec 13th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Sun Dec 21st 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 13th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 15th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 6 nights

Sun Dec 21st 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Mon Dec 22nd 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$4227

9:45pm - 11:50am
Wed Dec 17th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sun Dec 28th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Dec 17th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Dec 19th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 9 nights

Sun Dec 28th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Mon Dec 29th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4255

9:45pm - 11:50am
Sat Dec 20th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sun Dec 28th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Sat Dec 20th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Mon Dec 22nd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 6 nights

Sun Dec 28th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Mon Dec 29th 2025 Turkish Airlines · TK 801 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4276

9:45pm - 11:50am
Mon Dec 15th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Tue Dec 23rd 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 15th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 17th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 6 nights

Tue Dec 23rd 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Wed Dec 24th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$4443

9:45pm - 11:50am
Wed Dec 10th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Sat Dec 20th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Dec 12th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 8 nights

Sat Dec 20th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Sun Dec 21st 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)
US$4443

9:45pm - 11:50am
Wed Dec 10th 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Sun Dec 21st 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Wed Dec 10th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Fri Dec 12th 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 9 nights

Sun Dec 21st 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Mon Dec 22nd 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$4467

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 7:50pm
Fri Dec 19th 2025

33h 35m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 16 nights

Fri Dec 19th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 8h 15m

Sat Dec 20th 2025 Turkish Airlines · TK 903 Depart at 1:50pm from Istanbul (IST) Fly for 14h 0m Arrive at 7:50pm in Panama (PTY)
US$4508

9:45pm - 11:50am
Mon Dec 1st 2025

31h 5m
Panama (PTY) → Cape Town (CPT)

1 Stop

5:15pm - 5:05pm
Thu Dec 18th 2025

30h 50m
Cape Town (CPT) → Panama (PTY)

1 Stop

Mon Dec 1st 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)

Layover in Istanbul for 7h 20m

Wed Dec 3rd 2025 Turkish Airlines · TK 44 Depart at 1:55am from Istanbul (IST) Fly for 10h 55m Arrive at 11:50am in Cape Town (CPT)

Stay in Cape Town for 15 nights

Thu Dec 18th 2025 Turkish Airlines · TK 45 Depart at 5:15pm from Cape Town (CPT) Fly for 11h 20m Arrive at 5:35am in Istanbul (IST)

Layover in Istanbul for 2h 25m

Fri Dec 19th 2025 Turkish Airlines · TK 800 Depart at 8:00am from Istanbul (IST) Fly for 17h 5m Arrive at 5:05pm in Panama (PTY)

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality.

Andy Travels

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from Panama to South Africa (PA to ZA)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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