Flights from Panama to Italy (PA to IT)

Discover more affordable routes and cheaper dates from Panama to Italy (PA to IT) within a date range.

⭐ Search by country or region to discover more affordable routes, like Netherlands → Italy or Europe → South East Asia.

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US$405

10:05pm - 11:40am
Mon Jul 14th 2025

30h 35m
Panama (PTY) → Rome (FCO)

2 Stops

Mon Jul 14th 2025 Avianca · AV 57 Depart at 10:05pm from Panama (PTY) Fly for 1h 34m Arrive at 11:39pm in Bogotá (BOG)

Layover in Bogotá for 5h 26m

Tue Jul 15th 2025 Avianca · AV 6 Depart at 5:05am from Bogotá (BOG) Fly for 3h 45m Arrive at 9:50am in Miami (MIA)

Layover in Miami for 9h 40m

Tue Jul 15th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$405

5:25pm - 11:40am
Tue Jul 22nd 2025

35h 15m
Panama (PTY) → Rome (FCO)

2 Stops

Tue Jul 22nd 2025 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)

Layover in Bogotá for 4h 25m

Tue Jul 22nd 2025 Avianca · AV 8 Depart at 11:20pm from Bogotá (BOG) Fly for 3h 45m Arrive at 4:05am in Miami (MIA)

Layover in Miami for 15h 25m

Wed Jul 23rd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$439

3:25am - 11:40am
Tue Jul 15th 2025

25h 15m
Panama (PTY) → Rome (FCO)

2 Stops

Tue Jul 15th 2025 Avianca · AV 41 Depart at 3:25am from Panama (PTY) Fly for 1h 35m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 45m

Tue Jul 15th 2025 Avianca · AV 126 Depart at 7:45am from Bogotá (BOG) Fly for 3h 45m Arrive at 12:30pm in Miami (MIA)

Layover in Miami for 7h 0m

Tue Jul 15th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$439

3:25am - 11:40am
Tue Jul 22nd 2025

25h 15m
Panama (PTY) → Rome (FCO)

2 Stops

Tue Jul 22nd 2025 Avianca · AV 41 Depart at 3:25am from Panama (PTY) Fly for 1h 35m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 45m

Tue Jul 22nd 2025 Avianca · AV 126 Depart at 7:45am from Bogotá (BOG) Fly for 3h 45m Arrive at 12:30pm in Miami (MIA)

Layover in Miami for 7h 0m

Tue Jul 22nd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$439

3:20am - 11:40am
Mon Jul 14th 2025

25h 20m
Panama (PTY) → Rome (FCO)

2 Stops

Mon Jul 14th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 51m

Mon Jul 14th 2025 Avianca · AV 126 Depart at 7:45am from Bogotá (BOG) Fly for 3h 45m Arrive at 12:30pm in Miami (MIA)

Layover in Miami for 7h 0m

Mon Jul 14th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$439

10:05pm - 11:40am
Sat Jul 26th 2025

30h 35m
Panama (PTY) → Rome (FCO)

2 Stops

Sat Jul 26th 2025 Avianca · AV 57 Depart at 10:05pm from Panama (PTY) Fly for 1h 34m Arrive at 11:39pm in Bogotá (BOG)

Layover in Bogotá for 5h 26m

Sun Jul 27th 2025 Avianca · AV 6 Depart at 5:05am from Bogotá (BOG) Fly for 3h 45m Arrive at 9:50am in Miami (MIA)

Layover in Miami for 9h 55m

Sun Jul 27th 2025 ITA Airways · AZ 631 Depart at 7:45pm from Miami (MIA) Fly for 9h 55m Arrive at 11:40am in Rome (FCO)
US$439

10:05pm - 11:40am
Sun Jul 20th 2025

30h 35m
Panama (PTY) → Rome (FCO)

2 Stops

Sun Jul 20th 2025 Avianca · AV 57 Depart at 10:05pm from Panama (PTY) Fly for 1h 34m Arrive at 11:39pm in Bogotá (BOG)

Layover in Bogotá for 5h 26m

Mon Jul 21st 2025 Avianca · AV 6 Depart at 5:05am from Bogotá (BOG) Fly for 3h 45m Arrive at 9:50am in Miami (MIA)

Layover in Miami for 9h 40m

Mon Jul 21st 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$439

10:05pm - 11:40am
Mon Jul 21st 2025

30h 35m
Panama (PTY) → Rome (FCO)

2 Stops

Mon Jul 21st 2025 Avianca · AV 57 Depart at 10:05pm from Panama (PTY) Fly for 1h 34m Arrive at 11:39pm in Bogotá (BOG)

Layover in Bogotá for 5h 26m

Tue Jul 22nd 2025 Avianca · AV 6 Depart at 5:05am from Bogotá (BOG) Fly for 3h 45m Arrive at 9:50am in Miami (MIA)

Layover in Miami for 9h 40m

Tue Jul 22nd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$447

3:20am - 11:40am
Sun Jul 13th 2025

25h 20m
Panama (PTY) → Rome (FCO)

2 Stops

Sun Jul 13th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 51m

Sun Jul 13th 2025 Avianca · AV 126 Depart at 7:45am from Bogotá (BOG) Fly for 3h 45m Arrive at 12:30pm in Miami (MIA)

Layover in Miami for 7h 15m

Sun Jul 13th 2025 ITA Airways · AZ 631 Depart at 7:45pm from Miami (MIA) Fly for 9h 55m Arrive at 11:40am in Rome (FCO)
US$447

3:20am - 11:40am
Wed Jul 9th 2025

25h 20m
Panama (PTY) → Rome (FCO)

2 Stops

Wed Jul 9th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 51m

Wed Jul 9th 2025 Avianca · AV 126 Depart at 7:45am from Bogotá (BOG) Fly for 3h 45m Arrive at 12:30pm in Miami (MIA)

Layover in Miami for 7h 0m

Wed Jul 9th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$456

11:05am - 10:20am
Thu Jul 10th 2025

16h 15m
Panama (PTY) → Milan (LIN)

1 Stop

Thu Jul 10th 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 3h 55m

Fri Jul 11th 2025 easyJet · U2 1960 Depart at 9:10am from Frankfurt (FRA) Fly for 1h 10m Arrive at 10:20am in Milan (LIN)
US$481

11:05am - 10:20am
Mon Jul 28th 2025

16h 15m
Panama (PTY) → Milan (LIN)

1 Stop

Mon Jul 28th 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 3h 55m

Tue Jul 29th 2025 easyJet · U2 1960 Depart at 9:10am from Frankfurt (FRA) Fly for 1h 10m Arrive at 10:20am in Milan (LIN)
US$494

11:05am - 10:20am
Thu Jul 24th 2025

16h 15m
Panama (PTY) → Milan (LIN)

1 Stop

Thu Jul 24th 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 3h 55m

Fri Jul 25th 2025 easyJet · U2 1960 Depart at 9:10am from Frankfurt (FRA) Fly for 1h 10m Arrive at 10:20am in Milan (LIN)
US$500

3:25am - 7:15am
Tue Jul 22nd 2025

20h 50m
Panama (PTY) → Rome (FCO)

2 Stops

Tue Jul 22nd 2025 Avianca · AV 41 Depart at 3:25am from Panama (PTY) Fly for 1h 35m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 30m

Tue Jul 22nd 2025 Avianca · AV 246 Depart at 7:30am from Bogotá (BOG) Fly for 5h 30m Arrive at 2:00pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 2h 30m

Tue Jul 22nd 2025 ITA Airways · AZ 619 Depart at 4:30pm from Washington, D.C. (IAD) Fly for 8h 45m Arrive at 7:15am in Rome (FCO)
US$513

8:15am - 11:40am
Wed Jul 23rd 2025

20h 25m
Panama (BLB) → Rome (FCO)

2 Stops

Wed Jul 23rd 2025 Wingo airlines · P5 7043 Depart at 8:15am from Panama (BLB) Fly for 1h 18m Arrive at 9:33am in Medellín (MDE)

Layover in Medellín for 3h 2m

Wed Jul 23rd 2025 Avianca · AV 30 Depart at 12:35pm from Medellín (MDE) Fly for 3h 40m Arrive at 5:15pm in Miami (MIA)

Layover in Miami for 2h 15m

Wed Jul 23rd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$515

11:05am - 10:20am
Mon Jul 14th 2025

16h 15m
Panama (PTY) → Milan (LIN)

1 Stop

Mon Jul 14th 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 3h 55m

Tue Jul 15th 2025 easyJet · U2 1960 Depart at 9:10am from Frankfurt (FRA) Fly for 1h 10m Arrive at 10:20am in Milan (LIN)
US$517

12:48pm - 11:40am
Mon Jul 21st 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 21st 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Mon Jul 21st 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$517

12:48pm - 11:40am
Tue Jul 22nd 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 22nd 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Tue Jul 22nd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$520

11:05am - 2:05pm
Thu Jul 10th 2025

20h 0m
Panama (PTY) → Rome (FCO)

2 Stops

Thu Jul 10th 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 1h 30m

Fri Jul 11th 2025 Condor · DE 4179 Depart at 6:45am from Frankfurt (FRA) Fly for 1h 5m Arrive at 7:50am in Hamburg (HAM)

Layover in Hamburg for 4h 0m

Fri Jul 11th 2025 Eurowings · EW 7886 Depart at 11:50am from Hamburg (HAM) Fly for 2h 15m Arrive at 2:05pm in Rome (FCO)
US$525

11:05am - 10:20am
Thu Jul 31st 2025

16h 15m
Panama (PTY) → Milan (LIN)

1 Stop

Thu Jul 31st 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 3h 55m

Fri Aug 1st 2025 easyJet · U2 1960 Depart at 9:10am from Frankfurt (FRA) Fly for 1h 10m Arrive at 10:20am in Milan (LIN)
US$528

10:25am - 11:40am
Mon Jul 21st 2025

18h 15m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 21st 2025 Copa Airlines · CM 334 Depart at 10:25am from Panama (PTY) Fly for 3h 11m Arrive at 2:36pm in Miami (MIA)

Layover in Miami for 4h 54m

Mon Jul 21st 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$528

10:25am - 11:40am
Tue Jul 22nd 2025

18h 15m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 22nd 2025 Copa Airlines · CM 334 Depart at 10:25am from Panama (PTY) Fly for 3h 11m Arrive at 2:36pm in Miami (MIA)

Layover in Miami for 4h 54m

Tue Jul 22nd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$536

12:48pm - 11:40am
Tue Jul 29th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 29th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Tue Jul 29th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$536

12:48pm - 11:40am
Mon Jul 28th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 28th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Mon Jul 28th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$536

12:48pm - 11:40am
Sun Jul 27th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 27th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 46m

Sun Jul 27th 2025 ITA Airways · AZ 631 Depart at 7:45pm from Miami (MIA) Fly for 9h 55m Arrive at 11:40am in Rome (FCO)
US$536

12:48pm - 11:40am
Wed Jul 23rd 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Wed Jul 23rd 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Wed Jul 23rd 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$539

6:16pm - 7:05pm
Sun Aug 3rd 2025

17h 49m
Panama (PTY) → Rome (FCO)

2 Stops

Sun Aug 3rd 2025 Copa Airlines · CM 427 Depart at 6:16pm from Panama (PTY) Fly for 3h 10m Arrive at 10:26pm in Miami (MIA)

Layover in Miami for 2h 9m

Mon Aug 4th 2025 TAP Portugal · TP 226 Depart at 12:35am from Miami (MIA) Fly for 8h 20m Arrive at 1:55pm in Lisbon (LIS)

Layover in Lisbon for 1h 20m

Mon Aug 4th 2025 TAP Portugal · TP 836 Depart at 3:15pm from Lisbon (LIS) Fly for 2h 50m Arrive at 7:05pm in Rome (FCO)
US$540

7:29am - 7:05am
Mon Jul 14th 2025

16h 36m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 14th 2025 Copa Airlines · CM 704 Depart at 7:29am from Panama (PTY) Fly for 5h 39m Arrive at 2:08pm in Boston (BOS)

Layover in Boston for 2h 57m

Mon Jul 14th 2025 ITA Airways · AZ 615 Depart at 5:05pm from Boston (BOS) Fly for 8h 0m Arrive at 7:05am in Rome (FCO)
US$540

7:29am - 7:05am
Tue Jul 15th 2025

16h 36m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 15th 2025 Copa Airlines · CM 704 Depart at 7:29am from Panama (PTY) Fly for 5h 39m Arrive at 2:08pm in Boston (BOS)

Layover in Boston for 2h 57m

Tue Jul 15th 2025 ITA Airways · AZ 615 Depart at 5:05pm from Boston (BOS) Fly for 8h 0m Arrive at 7:05am in Rome (FCO)
US$540

7:29am - 7:05am
Sun Jul 20th 2025

16h 36m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 20th 2025 Copa Airlines · CM 704 Depart at 7:29am from Panama (PTY) Fly for 5h 39m Arrive at 2:08pm in Boston (BOS)

Layover in Boston for 2h 57m

Sun Jul 20th 2025 ITA Airways · AZ 615 Depart at 5:05pm from Boston (BOS) Fly for 8h 0m Arrive at 7:05am in Rome (FCO)
US$540

7:29am - 7:05am
Tue Jul 22nd 2025

16h 36m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 22nd 2025 Copa Airlines · CM 704 Depart at 7:29am from Panama (PTY) Fly for 5h 39m Arrive at 2:08pm in Boston (BOS)

Layover in Boston for 2h 57m

Tue Jul 22nd 2025 ITA Airways · AZ 615 Depart at 5:05pm from Boston (BOS) Fly for 8h 0m Arrive at 7:05am in Rome (FCO)
US$541

7:29am - 7:05am
Mon Jul 21st 2025

16h 36m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 21st 2025 Copa Airlines · CM 704 Depart at 7:29am from Panama (PTY) Fly for 5h 39m Arrive at 2:08pm in Boston (BOS)

Layover in Boston for 2h 57m

Mon Jul 21st 2025 ITA Airways · AZ 615 Depart at 5:05pm from Boston (BOS) Fly for 8h 0m Arrive at 7:05am in Rome (FCO)
US$546

11:05am - 10:20am
Mon Jul 21st 2025

16h 15m
Panama (PTY) → Milan (LIN)

1 Stop

Mon Jul 21st 2025 Condor · DE 2237 Depart at 11:05am from Panama (PTY) Fly for 11h 10m Arrive at 5:15am in Frankfurt (FRA)

Layover in Frankfurt for 3h 55m

Tue Jul 22nd 2025 easyJet · U2 1960 Depart at 9:10am from Frankfurt (FRA) Fly for 1h 10m Arrive at 10:20am in Milan (LIN)
US$564

12:48pm - 11:40am
Sun Jul 13th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 13th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 46m

Sun Jul 13th 2025 ITA Airways · AZ 631 Depart at 7:45pm from Miami (MIA) Fly for 9h 55m Arrive at 11:40am in Rome (FCO)
US$565

12:48pm - 11:40am
Mon Jul 14th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 14th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Mon Jul 14th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$565

12:48pm - 11:40am
Tue Jul 15th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 15th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Tue Jul 15th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$571

12:48pm - 11:40am
Thu Jul 24th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Thu Jul 24th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Thu Jul 24th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$571

12:48pm - 11:40am
Sat Jul 26th 2025

15h 52m
Panama (PTY) → Rome (FCO)

1 Stop

Sat Jul 26th 2025 Copa Airlines · CM 485 Depart at 12:48pm from Panama (PTY) Fly for 3h 11m Arrive at 4:59pm in Miami (MIA)

Layover in Miami for 2h 31m

Sat Jul 26th 2025 ITA Airways · AZ 631 Depart at 7:30pm from Miami (MIA) Fly for 10h 10m Arrive at 11:40am in Rome (FCO)
US$573

8:25pm - 5:15pm
Fri Jul 25th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Fri Jul 25th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Sat Jul 26th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Sun Jul 13th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Mon Jul 14th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Thu Jul 17th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Thu Jul 17th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Fri Jul 18th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Tue Jul 15th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Tue Jul 15th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Wed Jul 16th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Mon Jul 28th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 28th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Tue Jul 29th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Wed Jul 23rd 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Wed Jul 23rd 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Thu Jul 24th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Tue Jul 22nd 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Tue Jul 22nd 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Wed Jul 23rd 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Sun Jul 20th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 20th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Mon Jul 21st 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Sun Jul 27th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 27th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Mon Jul 28th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:15pm
Mon Jul 14th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 14th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Tue Jul 15th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$574

8:25pm - 5:25pm
Mon Jul 21st 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 21st 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Tue Jul 22nd 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Mon Jul 28th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 28th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Tue Jul 29th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Sun Jul 13th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Mon Jul 14th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Fri Jul 25th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Fri Jul 25th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Sat Jul 26th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Sun Jul 27th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 27th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Mon Jul 28th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Tue Jul 22nd 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 22nd 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Wed Jul 23rd 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Sun Jul 20th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 20th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Mon Jul 21st 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Thu Jul 17th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Thu Jul 17th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Fri Jul 18th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Tue Jul 15th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 15th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Wed Jul 16th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Mon Jul 14th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 14th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Tue Jul 15th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Wed Jul 23rd 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Wed Jul 23rd 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Thu Jul 24th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:25pm
Thu Jul 24th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Thu Jul 24th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Fri Jul 25th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$574

8:25pm - 5:35pm
Tue Jul 15th 2025

14h 10m
Panama (PTY) → Venice (VCE)

1 Stop

Tue Jul 15th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Wed Jul 16th 2025 Air Europa · UX 1083 Depart at 3:10pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:35pm in Venice (VCE)
US$574

8:25pm - 5:35pm
Sun Jul 13th 2025

14h 10m
Panama (PTY) → Venice (VCE)

1 Stop

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Mon Jul 14th 2025 Air Europa · UX 1083 Depart at 3:10pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:35pm in Venice (VCE)
US$575

8:25pm - 5:15pm
Thu Jul 24th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Thu Jul 24th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Fri Jul 25th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$575

6:50pm - 4:35pm
Mon Jul 14th 2025

14h 45m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 14th 2025 KLM Royal Dutch Airlines · KL 758 Depart at 6:50pm from Panama (PTY) Fly for 10h 20m Arrive at 12:10pm in Amsterdam (AMS)

Layover in Amsterdam for 2h 15m

Tue Jul 15th 2025 KLM Royal Dutch Airlines · KL 1605 Depart at 2:25pm from Amsterdam (AMS) Fly for 2h 10m Arrive at 4:35pm in Rome (FCO)
US$575

6:50pm - 4:35pm
Wed Jul 16th 2025

14h 45m
Panama (PTY) → Rome (FCO)

1 Stop

Wed Jul 16th 2025 KLM Royal Dutch Airlines · KL 758 Depart at 6:50pm from Panama (PTY) Fly for 10h 20m Arrive at 12:10pm in Amsterdam (AMS)

Layover in Amsterdam for 2h 15m

Thu Jul 17th 2025 KLM Royal Dutch Airlines · KL 1605 Depart at 2:25pm from Amsterdam (AMS) Fly for 2h 10m Arrive at 4:35pm in Rome (FCO)
US$575

6:50pm - 4:35pm
Thu Jul 17th 2025

14h 45m
Panama (PTY) → Rome (FCO)

1 Stop

Thu Jul 17th 2025 KLM Royal Dutch Airlines · KL 758 Depart at 6:50pm from Panama (PTY) Fly for 10h 20m Arrive at 12:10pm in Amsterdam (AMS)

Layover in Amsterdam for 2h 15m

Fri Jul 18th 2025 KLM Royal Dutch Airlines · KL 1605 Depart at 2:25pm from Amsterdam (AMS) Fly for 2h 10m Arrive at 4:35pm in Rome (FCO)
US$576

8:25pm - 5:15pm
Mon Jul 21st 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 21st 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Tue Jul 22nd 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$577

7:55pm - 5:30pm
Mon Jul 21st 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 21st 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Tue Jul 22nd 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$577

7:55pm - 5:30pm
Tue Jul 15th 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 15th 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Wed Jul 16th 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$577

7:55pm - 5:30pm
Sun Jul 20th 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 20th 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Mon Jul 21st 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$577

7:55pm - 5:30pm
Sat Jul 19th 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Sat Jul 19th 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Sun Jul 20th 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$577

7:55pm - 5:30pm
Mon Jul 14th 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 14th 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Tue Jul 15th 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$577

7:55pm - 5:30pm
Sun Jul 13th 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 13th 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Mon Jul 14th 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$584

8:25pm - 5:35pm
Mon Jul 7th 2025

14h 10m
Panama (PTY) → Venice (VCE)

1 Stop

Mon Jul 7th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Tue Jul 8th 2025 Air Europa · UX 1083 Depart at 3:10pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:35pm in Venice (VCE)
US$585

8:25pm - 5:15pm
Fri Jul 11th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Sat Jul 12th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$585

8:25pm - 5:25pm
Mon Jul 7th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Mon Jul 7th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Tue Jul 8th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$585

8:25pm - 5:25pm
Tue Jul 8th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Tue Jul 8th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Wed Jul 9th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$585

8:25pm - 5:25pm
Wed Jul 9th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Thu Jul 10th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$585

8:25pm - 5:25pm
Sun Jul 6th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 6th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Mon Jul 7th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$585

8:25pm - 5:25pm
Thu Jul 10th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Thu Jul 10th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Fri Jul 11th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$585

8:25pm - 5:25pm
Fri Jul 11th 2025

14h 0m
Panama (PTY) → Rome (FCO)

1 Stop

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 45m

Sat Jul 12th 2025 Air Europa · UX 1047 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:25pm in Rome (FCO)
US$585

8:25pm - 5:35pm
Sun Jul 6th 2025

14h 10m
Panama (PTY) → Venice (VCE)

1 Stop

Sun Jul 6th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Mon Jul 7th 2025 Air Europa · UX 1083 Depart at 3:10pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:35pm in Venice (VCE)
US$585

8:25pm - 5:35pm
Wed Jul 9th 2025

14h 10m
Panama (PTY) → Venice (VCE)

1 Stop

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Thu Jul 10th 2025 Air Europa · UX 1083 Depart at 3:10pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:35pm in Venice (VCE)
US$586

8:25pm - 5:35pm
Fri Jul 11th 2025

14h 10m
Panama (PTY) → Venice (VCE)

1 Stop

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Sat Jul 12th 2025 Air Europa · UX 1083 Depart at 3:10pm from Madrid (MAD) Fly for 2h 25m Arrive at 5:35pm in Venice (VCE)
US$587

8:25pm - 5:15pm
Wed Jul 9th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Thu Jul 10th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$587

8:25pm - 5:15pm
Sun Jul 6th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 6th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Mon Jul 7th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$587

8:25pm - 5:15pm
Tue Jul 8th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Tue Jul 8th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Wed Jul 9th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$587

8:25pm - 5:15pm
Thu Jul 10th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Thu Jul 10th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Fri Jul 11th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$587

8:25pm - 5:15pm
Mon Jul 7th 2025

13h 50m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 7th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Layover in Madrid for 1h 55m

Tue Jul 8th 2025 Air Europa · UX 1061 Depart at 3:10pm from Madrid (MAD) Fly for 2h 5m Arrive at 5:15pm in Milan (MXP)
US$588

7:55pm - 5:30pm
Sun Jul 6th 2025

14h 35m
Panama (PTY) → Rome (FCO)

1 Stop

Sun Jul 6th 2025 Air France · AF 475 Depart at 7:55pm from Panama (PTY) Fly for 10h 20m Arrive at 1:15pm in Paris (CDG)

Layover in Paris for 2h 10m

Mon Jul 7th 2025 Air France · AF 1604 Depart at 3:25pm from Paris (CDG) Fly for 2h 5m Arrive at 5:30pm in Rome (FCO)
US$695

5:10pm - 1:40pm
Sun Jul 13th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 13th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Mon Jul 14th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Mon Jul 28th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 28th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Jul 29th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Thu Jul 31st 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Thu Jul 31st 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Fri Aug 1st 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Mon Jul 14th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 14th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Jul 15th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Sun Jul 20th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 20th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Mon Jul 21st 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Sun Jul 27th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Sun Jul 27th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Mon Jul 28th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Mon Jul 21st 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 21st 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Jul 22nd 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$695

5:10pm - 1:40pm
Thu Jul 17th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Thu Jul 17th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Fri Jul 18th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$708

5:10pm - 1:40pm
Thu Jul 10th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Thu Jul 10th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Fri Jul 11th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)
US$708

5:10pm - 1:40pm
Mon Jul 7th 2025

13h 30m
Panama (PTY) → Milan (MXP)

1 Stop

Mon Jul 7th 2025 Iberia Airlines · IB 258 Depart at 5:10pm from Panama (PTY) Fly for 10h 5m Arrive at 10:15am in Madrid (MAD)

Layover in Madrid for 1h 15m

Tue Jul 8th 2025 Iberia Airlines · IB 673 Depart at 11:30am from Madrid (MAD) Fly for 2h 10m Arrive at 1:40pm in Milan (MXP)

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality.

Andy Travels

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from Panama to Italy (PA to IT)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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