Cheap Flights from Panama City to Madrid (PTY to MAD)

Discover more affordable routes and cheaper dates from Panama City to Madrid (PTY to MAD) within a date range.

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US$1143

12:55pm - 10:50am
Wed Jul 9th 2025

14h 55m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Iberia Airlines · IB 7740 Depart at 12:55pm from Panama (PTY) Fly for 1h 25m Arrive at 1:20pm in San José (SJO)

Layover in San José for 2h 50m

Wed Jul 9th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

12:55pm - 10:50am
Tue Jul 8th 2025

14h 55m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Iberia Airlines · IB 7740 Depart at 12:55pm from Panama (PTY) Fly for 1h 25m Arrive at 1:20pm in San José (SJO)

Layover in San José for 2h 50m

Tue Jul 8th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

9:34am - 10:50am
Tue Jul 8th 2025

18h 16m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Iberia Airlines · IB 7731 Depart at 9:34am from Panama (PTY) Fly for 1h 25m Arrive at 9:59am in San José (SJO)

Layover in San José for 6h 11m

Tue Jul 8th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

9:34am - 10:50am
Wed Jul 9th 2025

18h 16m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Iberia Airlines · IB 7731 Depart at 9:34am from Panama (PTY) Fly for 1h 25m Arrive at 9:59am in San José (SJO)

Layover in San José for 6h 11m

Wed Jul 9th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

7:55am - 10:50am
Tue Jul 8th 2025

19h 55m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Iberia Airlines · IB 7747 Depart at 7:55am from Panama (PTY) Fly for 1h 25m Arrive at 8:20am in San José (SJO)

Layover in San José for 7h 50m

Tue Jul 8th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

7:55am - 10:50am
Wed Jul 9th 2025

19h 55m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Iberia Airlines · IB 7747 Depart at 7:55am from Panama (PTY) Fly for 1h 25m Arrive at 8:20am in San José (SJO)

Layover in San José for 7h 50m

Wed Jul 9th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

7:10am - 10:50am
Tue Jul 8th 2025

20h 40m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Iberia Airlines · IB 7755 Depart at 7:10am from Panama (PTY) Fly for 1h 25m Arrive at 7:35am in San José (SJO)

Layover in San José for 8h 35m

Tue Jul 8th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1143

7:10am - 10:50am
Wed Jul 9th 2025

20h 40m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Iberia Airlines · IB 7755 Depart at 7:10am from Panama (PTY) Fly for 1h 25m Arrive at 7:35am in San José (SJO)

Layover in San José for 8h 35m

Wed Jul 9th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1160

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 8:00pm
Thu Jul 17th 2025

39h 0m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Turkish Airlines · TK 1858 Depart at 12:00pm from Madrid (MAD) Fly for 4h 10m Arrive at 5:10pm in Istanbul (IST)

Layover in Istanbul for 21h 0m

Fri Jul 18th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1164

1:55pm - 12:45pm
Tue Jul 8th 2025

15h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Iberia Airlines · IB 4369 Depart at 1:55pm from Panama (PTY) Fly for 3h 5m Arrive at 6:00pm in Miami (MIA)

Layover in Miami for 3h 55m

Tue Jul 8th 2025 Iberia Airlines · IB 338 Depart at 9:55pm from Miami (MIA) Fly for 8h 50m Arrive at 12:45pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1164

1:55pm - 12:45pm
Wed Jul 9th 2025

15h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Iberia Airlines · IB 4369 Depart at 1:55pm from Panama (PTY) Fly for 3h 5m Arrive at 6:00pm in Miami (MIA)

Layover in Miami for 3h 55m

Wed Jul 9th 2025 Iberia Airlines · IB 338 Depart at 9:55pm from Miami (MIA) Fly for 8h 50m Arrive at 12:45pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1227

9:55pm - 10:25am
Wed Jul 9th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

11:00pm - 8:00pm
Tue Jul 15th 2025

28h 0m
Madrid (MAD) → Panama (PTY)

2 Stops

Wed Jul 9th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Fri Jul 11th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 4 nights

Tue Jul 15th 2025 Iberia Airlines · IB 539 Depart at 11:00pm from Madrid (MAD) Fly for 1h 25m Arrive at 11:25pm in Lisbon (LIS)

Layover in Lisbon for 6h 30m

Wed Jul 16th 2025 Turkish Airlines · TK 1780 Depart at 5:55am from Lisbon (LIS) Fly for 4h 50m Arrive at 12:45pm in Istanbul (IST)

Layover in Istanbul for 1h 25m

Wed Jul 16th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1227

9:55pm - 10:25am
Sun Jul 13th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

11:00pm - 8:00pm
Tue Jul 15th 2025

28h 0m
Madrid (MAD) → Panama (PTY)

2 Stops

Sun Jul 13th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Tue Jul 15th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 0 nights

Tue Jul 15th 2025 Iberia Airlines · IB 539 Depart at 11:00pm from Madrid (MAD) Fly for 1h 25m Arrive at 11:25pm in Lisbon (LIS)

Layover in Lisbon for 6h 30m

Wed Jul 16th 2025 Turkish Airlines · TK 1780 Depart at 5:55am from Lisbon (LIS) Fly for 4h 50m Arrive at 12:45pm in Istanbul (IST)

Layover in Istanbul for 1h 25m

Wed Jul 16th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1233

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

2:45pm - 8:00pm
Thu Jul 17th 2025

36h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Turkish Airlines · TK 1358 Depart at 2:45pm from Madrid (MAD) Fly for 4h 15m Arrive at 8:00pm in Istanbul (IST)

Layover in Istanbul for 18h 10m

Fri Jul 18th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1233

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

2:45pm - 8:00pm
Tue Jul 15th 2025

36h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 5 nights

Tue Jul 15th 2025 Turkish Airlines · TK 1358 Depart at 2:45pm from Madrid (MAD) Fly for 4h 15m Arrive at 8:00pm in Istanbul (IST)

Layover in Istanbul for 18h 10m

Wed Jul 16th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1233

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 8:00pm
Tue Jul 15th 2025

39h 0m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 5 nights

Tue Jul 15th 2025 Turkish Airlines · TK 1858 Depart at 12:00pm from Madrid (MAD) Fly for 4h 10m Arrive at 5:10pm in Istanbul (IST)

Layover in Istanbul for 21h 0m

Wed Jul 16th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1236

11:05am - 4:00pm
Wed Jul 9th 2025

21h 55m
Panama (PTY) → Madrid (MAD)

2 Stops

2:55pm - 12:10am
Thu Jul 17th 2025

16h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 59 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 7h 50m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 8:25pm from Bogotá (BOG) Fly for 1h 30m Arrive at 9:55pm in Cartagena (CTG)

Layover in Cartagena for 1h 20m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 11:15pm from Cartagena (CTG) Fly for 9h 45m Arrive at 4:00pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Plus Ultra Lineas Aereas · PU 231 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 4h 0m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1236

11:05am - 4:00pm
Wed Jul 9th 2025

21h 55m
Panama (PTY) → Madrid (MAD)

2 Stops

2:55pm - 12:45am
Wed Jul 16th 2025

16h 50m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 59 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 7h 50m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 8:25pm from Bogotá (BOG) Fly for 1h 30m Arrive at 9:55pm in Cartagena (CTG)

Layover in Cartagena for 1h 20m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 11:15pm from Cartagena (CTG) Fly for 9h 45m Arrive at 4:00pm in Madrid (MAD)

Stay in Madrid for 5 nights

Wed Jul 16th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 4h 35m

Wed Jul 16th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1238

3:48pm - 4:00pm
Thu Jul 10th 2025

17h 12m
Panama (PTY) → Madrid (MAD)

2 Stops

2:55pm - 12:10am
Thu Jul 17th 2025

16h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Thu Jul 10th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 59m

Thu Jul 10th 2025 Plus Ultra Lineas Aereas · PU 231 Depart at 8:25pm from Bogotá (BOG) Fly for 1h 30m Arrive at 9:55pm in Cartagena (CTG)

Layover in Cartagena for 1h 20m

Thu Jul 10th 2025 Plus Ultra Lineas Aereas · PU 231 Depart at 11:15pm from Cartagena (CTG) Fly for 9h 45m Arrive at 4:00pm in Madrid (MAD)

Stay in Madrid for 5 nights

Thu Jul 17th 2025 Plus Ultra Lineas Aereas · PU 231 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 4h 0m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1240

3:48pm - 4:00pm
Wed Jul 9th 2025

17h 12m
Panama (PTY) → Madrid (MAD)

2 Stops

2:55pm - 12:10am
Thu Jul 17th 2025

16h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 59m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 8:25pm from Bogotá (BOG) Fly for 1h 30m Arrive at 9:55pm in Cartagena (CTG)

Layover in Cartagena for 1h 20m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 11:15pm from Cartagena (CTG) Fly for 9h 45m Arrive at 4:00pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Plus Ultra Lineas Aereas · PU 231 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 4h 0m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1240

3:48pm - 4:00pm
Wed Jul 9th 2025

17h 12m
Panama (PTY) → Madrid (MAD)

2 Stops

2:55pm - 12:45am
Wed Jul 16th 2025

16h 50m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 59m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 8:25pm from Bogotá (BOG) Fly for 1h 30m Arrive at 9:55pm in Cartagena (CTG)

Layover in Cartagena for 1h 20m

Wed Jul 9th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 11:15pm from Cartagena (CTG) Fly for 9h 45m Arrive at 4:00pm in Madrid (MAD)

Stay in Madrid for 5 nights

Wed Jul 16th 2025 Plus Ultra Lineas Aereas · PU 221 Depart at 2:55pm from Madrid (MAD) Fly for 10h 30m Arrive at 6:25pm in Bogotá (BOG)

Layover in Bogotá for 4h 35m

Wed Jul 16th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1243

9:55pm - 10:25am
Sun Jul 13th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Tue Jul 15th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 3 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1243

9:55pm - 10:25am
Wed Jul 9th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Fri Jul 11th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 7 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1243

9:55pm - 10:25am
Sun Jul 13th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Tue Jul 15th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 2 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1286

9:55pm - 10:25am
Sun Jul 13th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Tue Jul 15th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 2 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1286

9:55pm - 10:25am
Wed Jul 9th 2025

29h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Turkish Airlines · TK 904 Depart at 9:55pm from Panama (PTY) Fly for 12h 45m Arrive at 6:40pm in Istanbul (IST)

Layover in Istanbul for 12h 15m

Fri Jul 11th 2025 Turkish Airlines · TK 1857 Depart at 6:55am from Istanbul (IST) Fly for 4h 30m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1299

3:40pm - 3:30pm
Sun Jul 13th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Sun Jul 13th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 3 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1299

3:40pm - 3:30pm
Fri Jul 11th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Fri Jul 11th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 5 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1299

3:40pm - 3:30pm
Sun Jul 13th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Sun Jul 13th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 2 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1299

3:40pm - 3:30pm
Fri Jul 11th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Fri Jul 11th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 4 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1323

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

6:20pm - 8:00pm
Tue Jul 15th 2025

32h 40m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 5 nights

Tue Jul 15th 2025 Turkish Airlines · TK 1860 Depart at 6:20pm from Madrid (MAD) Fly for 4h 15m Arrive at 11:35pm in Istanbul (IST)

Layover in Istanbul for 14h 35m

Wed Jul 16th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1332

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

11:00pm - 8:00pm
Tue Jul 15th 2025

28h 0m
Madrid (MAD) → Panama (PTY)

2 Stops

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 6 nights

Tue Jul 15th 2025 Iberia Airlines · IB 539 Depart at 11:00pm from Madrid (MAD) Fly for 1h 25m Arrive at 11:25pm in Lisbon (LIS)

Layover in Lisbon for 6h 30m

Wed Jul 16th 2025 Turkish Airlines · TK 1780 Depart at 5:55am from Lisbon (LIS) Fly for 4h 50m Arrive at 12:45pm in Istanbul (IST)

Layover in Istanbul for 1h 25m

Wed Jul 16th 2025 Turkish Airlines · TK 903 Depart at 2:10pm from Istanbul (IST) Fly for 13h 50m Arrive at 8:00pm in Panama (PTY)

Book Flight
US$1337

9:45am - 9:00am
Tue Jul 8th 2025

16h 15m
Panama (PTY) → Madrid (MAD)

1 Stop

6:00am - 7:31pm
Tue Jul 15th 2025

20h 31m
Madrid (MAD) → Panama (PTY)

2 Stops

Tue Jul 8th 2025 United Airlines · UA 727 Depart at 9:45am from Panama (PTY) Fly for 5h 28m Arrive at 4:13pm in New York (EWR)

Layover in New York for 3h 7m

Tue Jul 8th 2025 United Airlines · UA 51 Depart at 7:20pm from New York (EWR) Fly for 7h 40m Arrive at 9:00am in Madrid (MAD)

Stay in Madrid for 5 nights

Tue Jul 15th 2025 United Airlines · UA 8982 Depart at 6:00am from Madrid (MAD) Fly for 2h 35m Arrive at 8:35am in Frankfurt (FRA)

Layover in Frankfurt for 2h 35m

Tue Jul 15th 2025 United Airlines · UA 43 Depart at 11:10am from Frankfurt (FRA) Fly for 8h 30m Arrive at 1:40pm in New York (EWR)

Layover in New York for 1h 31m

Tue Jul 15th 2025 United Airlines · UA 1021 Depart at 3:11pm from New York (EWR) Fly for 5h 20m Arrive at 7:31pm in Panama (PTY)

Book Flight
US$1342

3:40pm - 3:30pm
Fri Jul 11th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Fri Jul 11th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 4 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1342

3:40pm - 3:30pm
Sun Jul 13th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Sun Jul 13th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 2 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Thu Jul 10th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Thu Jul 10th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 7 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Thu Jul 10th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Thu Jul 10th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Sat Jul 12th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sat Jul 12th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 5 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Wed Jul 9th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 8 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Fri Jul 11th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 6 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Sun Jul 13th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 4 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Tue Jul 8th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 9 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Sun Jul 13th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 3 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Sat Jul 12th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sat Jul 12th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 4 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Fri Jul 11th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 5 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Tue Jul 8th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1343

8:25pm - 1:15pm
Wed Jul 9th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:25am - 11:30pm
Tue Jul 8th 2025

13h 5m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Avianca · AV 41 Depart at 3:25am from Panama (PTY) Fly for 1h 35m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 0m

Tue Jul 8th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 9 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:25am - 11:30pm
Tue Jul 8th 2025

13h 5m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Avianca · AV 41 Depart at 3:25am from Panama (PTY) Fly for 1h 35m Arrive at 5:00am in Bogotá (BOG)

Layover in Bogotá for 2h 0m

Tue Jul 8th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Thu Jul 10th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Thu Jul 10th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Thu Jul 10th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 7 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Thu Jul 10th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Thu Jul 10th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Thu Jul 10th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Sun Jul 13th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Sun Jul 13th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 4 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Fri Jul 11th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Fri Jul 11th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 6 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Wed Jul 9th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Wed Jul 9th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 8 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Fri Jul 11th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Fri Jul 11th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 5 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Wed Jul 9th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Wed Jul 9th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

3:20am - 11:30pm
Sun Jul 13th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Sun Jul 13th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 3 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

11:05am - 7:40am
Wed Jul 9th 2025

13h 35m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Avianca · AV 59 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Wed Jul 9th 2025 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)

Stay in Madrid for 8 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

11:05am - 7:40am
Fri Jul 11th 2025

13h 35m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 8383 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Fri Jul 11th 2025 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)

Stay in Madrid for 6 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

11:05am - 7:40am
Sun Jul 13th 2025

13h 35m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Fri Jul 18th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 8383 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Sun Jul 13th 2025 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)

Stay in Madrid for 4 nights

Fri Jul 18th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

11:05am - 7:40am
Fri Jul 11th 2025

13h 35m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 8383 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Fri Jul 11th 2025 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)

Stay in Madrid for 5 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

11:05am - 7:40am
Wed Jul 9th 2025

13h 35m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Avianca · AV 59 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Wed Jul 9th 2025 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1365

11:05am - 7:40am
Sun Jul 13th 2025

13h 35m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Thu Jul 17th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 8383 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Sun Jul 13th 2025 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)

Stay in Madrid for 3 nights

Thu Jul 17th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1368

3:40pm - 3:30pm
Fri Jul 11th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Fri Jul 11th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 3 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1368

3:40pm - 3:30pm
Sun Jul 13th 2025

16h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Avianca · AV 317 Depart at 3:40pm from Panama (PTY) Fly for 1h 15m Arrive at 4:55pm in Medellín (MDE)

Layover in Medellín for 6h 5m

Sun Jul 13th 2025 Avianca · AV 16 Depart at 11:00pm from Medellín (MDE) Fly for 9h 30m Arrive at 3:30pm in Madrid (MAD)

Stay in Madrid for 1 night

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1386

8:25pm - 1:15pm
Thu Jul 10th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Thu Jul 10th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 5 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1386

8:25pm - 1:15pm
Sun Jul 13th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 2 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1386

8:25pm - 1:15pm
Tue Jul 8th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1386

8:25pm - 1:15pm
Sat Jul 12th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Sat Jul 12th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 3 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1386

8:25pm - 1:15pm
Wed Jul 9th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1386

8:25pm - 1:15pm
Fri Jul 11th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 4 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1387

8:00pm - 10:30pm
Tue Jul 8th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Turkish Airlines · TK 900 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Wed Jul 9th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1387

8:00pm - 10:30pm
Sun Jul 13th 2025

19h 30m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Turkish Airlines · TK 800 Depart at 8:00pm from Panama (PTY) Fly for 12h 55m Arrive at 4:55pm in Istanbul (IST)

Layover in Istanbul for 2h 0m

Mon Jul 14th 2025 Turkish Airlines · TK 1359 Depart at 6:55pm from Istanbul (IST) Fly for 4h 35m Arrive at 10:30pm in Madrid (MAD)

Stay in Madrid for 2 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1412

8:25pm - 1:15pm
Thu Jul 10th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Thu Jul 10th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 5 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1412

8:25pm - 1:15pm
Sun Jul 13th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 2 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1412

8:25pm - 1:15pm
Tue Jul 8th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 7 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1412

8:25pm - 1:15pm
Wed Jul 9th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 6 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1412

8:25pm - 1:15pm
Fri Jul 11th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Fri Jul 11th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 4 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1412

8:25pm - 1:15pm
Sat Jul 12th 2025

9h 50m
Panama (PTY) → Madrid (MAD)

Direct

3:05pm - 6:40pm
Wed Jul 16th 2025

10h 35m
Madrid (MAD) → Panama (PTY)

Direct

Sat Jul 12th 2025 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)

Stay in Madrid for 3 nights

Wed Jul 16th 2025 Air Europa · UX 55 Depart at 3:05pm from Madrid (MAD) Fly for 10h 35m Arrive at 6:40pm in Panama (PTY)

Book Flight
US$1429

1:28pm - 10:50am
Wed Jul 9th 2025

14h 22m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Wed Jul 9th 2025 Copa Airlines · CM 342 Depart at 1:28pm from Panama (PTY) Fly for 1h 26m Arrive at 1:54pm in San José (SJO)

Layover in San José for 2h 16m

Wed Jul 9th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1429

1:28pm - 10:50am
Tue Jul 8th 2025

14h 22m
Panama (PTY) → Madrid (MAD)

1 Stop

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Tue Jul 8th 2025 Copa Airlines · CM 342 Depart at 1:28pm from Panama (PTY) Fly for 1h 26m Arrive at 1:54pm in San José (SJO)

Layover in San José for 2h 16m

Tue Jul 8th 2025 Iberia Airlines · IB 244 Depart at 4:10pm from San José (SJO) Fly for 10h 40m Arrive at 10:50am in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1509

5:20pm - 10:25am
Sun Jul 13th 2025

10h 5m
Panama (PTY) → Madrid (MAD)

Direct

12:00pm - 3:40pm
Thu Jul 17th 2025

10h 40m
Madrid (MAD) → Panama (PTY)

Direct

Sun Jul 13th 2025 Iberia Airlines · IB 258 Depart at 5:20pm from Panama (PTY) Fly for 10h 5m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 3 nights

Thu Jul 17th 2025 Iberia Airlines · IB 257 Depart at 12:00pm from Madrid (MAD) Fly for 10h 40m Arrive at 3:40pm in Panama (PTY)

Book Flight
US$1573

5:20pm - 10:25am
Thu Jul 10th 2025

10h 5m
Panama (PTY) → Madrid (MAD)

Direct

11:30am - 8:15pm
Wed Jul 16th 2025

15h 45m
Madrid (MAD) → Panama (PTY)

1 Stop

Thu Jul 10th 2025 Iberia Airlines · IB 258 Depart at 5:20pm from Panama (PTY) Fly for 10h 5m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 5 nights

Wed Jul 16th 2025 Iberia Airlines · IB 243 Depart at 11:30am from Madrid (MAD) Fly for 11h 5m Arrive at 2:35pm in San José (SJO)

Layover in San José for 3h 17m

Wed Jul 16th 2025 Iberia Airlines · IB 7730 Depart at 5:52pm from San José (SJO) Fly for 1h 23m Arrive at 8:15pm in Panama (PTY)

Book Flight
US$1573

5:20pm - 10:25am
Thu Jul 10th 2025

10h 5m
Panama (PTY) → Madrid (MAD)

Direct

11:30am - 8:30pm
Wed Jul 16th 2025

16h 0m
Madrid (MAD) → Panama (PTY)

1 Stop

Thu Jul 10th 2025 Iberia Airlines · IB 258 Depart at 5:20pm from Panama (PTY) Fly for 10h 5m Arrive at 10:25am in Madrid (MAD)

Stay in Madrid for 5 nights

Wed Jul 16th 2025 Iberia Airlines · IB 243 Depart at 11:30am from Madrid (MAD) Fly for 11h 5m Arrive at 2:35pm in San José (SJO)

Layover in San José for 3h 32m

Wed Jul 16th 2025 Iberia Airlines · IB 7769 Depart at 6:07pm from San José (SJO) Fly for 1h 23m Arrive at 8:30pm in Panama (PTY)

Book Flight
US$1663

3:48pm - 1:00pm
Sun Jul 13th 2025

14h 12m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:45am
Fri Jul 18th 2025

16h 30m
Madrid (MAD) → Panama (PTY)

1 Stop

Sun Jul 13th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Sun Jul 13th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 4 nights

Fri Jul 18th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 45m

Fri Jul 18th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1664

11:05am - 1:00pm
Wed Jul 9th 2025

18h 55m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:10am
Thu Jul 17th 2025

15h 55m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 59 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)

Layover in Bogotá for 7h 40m

Wed Jul 9th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 10m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1665

3:48pm - 1:00pm
Thu Jul 10th 2025

14h 12m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:10am
Thu Jul 17th 2025

15h 55m
Madrid (MAD) → Panama (PTY)

1 Stop

Thu Jul 10th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Thu Jul 10th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 10m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1665

11:51am - 1:00pm
Tue Jul 8th 2025

18h 9m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:45am
Fri Jul 18th 2025

16h 30m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Copa Airlines · CM 415 Depart at 11:51am from Panama (PTY) Fly for 1h 38m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 6h 46m

Tue Jul 8th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 9 nights

Fri Jul 18th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 45m

Fri Jul 18th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1666

3:48pm - 1:00pm
Wed Jul 9th 2025

14h 12m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:45am
Fri Jul 18th 2025

16h 30m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Wed Jul 9th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 8 nights

Fri Jul 18th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 45m

Fri Jul 18th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1667

11:51am - 1:00pm
Tue Jul 8th 2025

18h 9m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:10am
Thu Jul 17th 2025

15h 55m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Copa Airlines · CM 415 Depart at 11:51am from Panama (PTY) Fly for 1h 38m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 6h 46m

Tue Jul 8th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 10m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1667

3:48pm - 1:00pm
Wed Jul 9th 2025

14h 12m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:10am
Thu Jul 17th 2025

15h 55m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Wed Jul 9th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 10m

Thu Jul 17th 2025 Avianca · AV 40 Depart at 10:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:10am in Panama (PTY)

Book Flight
US$1668

3:48pm - 1:00pm
Wed Jul 9th 2025

14h 12m
Panama (PTY) → Madrid (MAD)

1 Stop

3:15pm - 12:45am
Wed Jul 16th 2025

16h 30m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Wed Jul 9th 2025 Air Europa · UX 194 Depart at 8:15pm from Bogotá (BOG) Fly for 9h 45m Arrive at 1:00pm in Madrid (MAD)

Stay in Madrid for 6 nights

Wed Jul 16th 2025 Air Europa · UX 193 Depart at 3:15pm from Madrid (MAD) Fly for 10h 0m Arrive at 6:15pm in Bogotá (BOG)

Layover in Bogotá for 4h 45m

Wed Jul 16th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1694

5:25pm - 2:15pm
Wed Jul 9th 2025

13h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:10pm - 9:10pm
Thu Jul 17th 2025

16h 0m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Wed Jul 9th 2025 LATAM Airlines · LA 1575 Depart at 9:30pm from Bogotá (BOG) Fly for 9h 45m Arrive at 2:15pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 LATAM Airlines · LA 1581 Depart at 12:10pm from Madrid (MAD) Fly for 10h 30m Arrive at 3:40pm in Bogotá (BOG)

Layover in Bogotá for 3h 45m

Thu Jul 17th 2025 Avianca · AV 56 Depart at 7:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 9:10pm in Panama (PTY)

Book Flight
US$1696

5:25pm - 2:15pm
Wed Jul 9th 2025

13h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:10pm - 8:04pm
Thu Jul 17th 2025

14h 54m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Wed Jul 9th 2025 LATAM Airlines · LA 1575 Depart at 9:30pm from Bogotá (BOG) Fly for 9h 45m Arrive at 2:15pm in Madrid (MAD)

Stay in Madrid for 6 nights

Thu Jul 17th 2025 LATAM Airlines · LA 1581 Depart at 12:10pm from Madrid (MAD) Fly for 10h 30m Arrive at 3:40pm in Bogotá (BOG)

Layover in Bogotá for 2h 37m

Thu Jul 17th 2025 Copa Airlines · CM 414 Depart at 6:17pm from Bogotá (BOG) Fly for 1h 47m Arrive at 8:04pm in Panama (PTY)

Book Flight
US$1699

5:25pm - 2:15pm
Tue Jul 8th 2025

13h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:10pm - 9:10pm
Thu Jul 17th 2025

16h 0m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Tue Jul 8th 2025 LATAM Airlines · LA 1575 Depart at 9:30pm from Bogotá (BOG) Fly for 9h 45m Arrive at 2:15pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 LATAM Airlines · LA 1581 Depart at 12:10pm from Madrid (MAD) Fly for 10h 30m Arrive at 3:40pm in Bogotá (BOG)

Layover in Bogotá for 3h 45m

Thu Jul 17th 2025 Avianca · AV 56 Depart at 7:25pm from Bogotá (BOG) Fly for 1h 45m Arrive at 9:10pm in Panama (PTY)

Book Flight
US$1699

3:48pm - 2:15pm
Thu Jul 10th 2025

15h 27m
Panama (PTY) → Madrid (MAD)

1 Stop

12:10pm - 8:04pm
Thu Jul 17th 2025

14h 54m
Madrid (MAD) → Panama (PTY)

1 Stop

Thu Jul 10th 2025 Copa Airlines · CM 411 Depart at 3:48pm from Panama (PTY) Fly for 1h 38m Arrive at 5:26pm in Bogotá (BOG)

Layover in Bogotá for 4h 4m

Thu Jul 10th 2025 Iberia Airlines · IB 154 Depart at 9:30pm from Bogotá (BOG) Fly for 9h 45m Arrive at 2:15pm in Madrid (MAD)

Stay in Madrid for 5 nights

Thu Jul 17th 2025 Iberia Airlines · IB 151 Depart at 12:10pm from Madrid (MAD) Fly for 10h 30m Arrive at 3:40pm in Bogotá (BOG)

Layover in Bogotá for 2h 37m

Thu Jul 17th 2025 Copa Airlines · CM 414 Depart at 6:17pm from Bogotá (BOG) Fly for 1h 47m Arrive at 8:04pm in Panama (PTY)

Book Flight
US$1701

5:25pm - 2:15pm
Tue Jul 8th 2025

13h 50m
Panama (PTY) → Madrid (MAD)

1 Stop

12:10pm - 8:04pm
Thu Jul 17th 2025

14h 54m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Tue Jul 8th 2025 LATAM Airlines · LA 1575 Depart at 9:30pm from Bogotá (BOG) Fly for 9h 45m Arrive at 2:15pm in Madrid (MAD)

Stay in Madrid for 7 nights

Thu Jul 17th 2025 LATAM Airlines · LA 1581 Depart at 12:10pm from Madrid (MAD) Fly for 10h 30m Arrive at 3:40pm in Bogotá (BOG)

Layover in Bogotá for 2h 37m

Thu Jul 17th 2025 Copa Airlines · CM 414 Depart at 6:17pm from Bogotá (BOG) Fly for 1h 47m Arrive at 8:04pm in Panama (PTY)

Book Flight
US$1704

11:51am - 10:00am
Tue Jul 8th 2025

15h 9m
Panama (PTY) → Madrid (MAD)

1 Stop

12:10pm - 8:04pm
Thu Jul 17th 2025

14h 54m
Madrid (MAD) → Panama (PTY)

1 Stop

Tue Jul 8th 2025 Copa Airlines · CM 415 Depart at 11:51am from Panama (PTY) Fly for 1h 38m Arrive at 1:29pm in Bogotá (BOG)

Layover in Bogotá for 3h 51m

Tue Jul 8th 2025 LATAM Airlines · LA 1580 Depart at 5:20pm from Bogotá (BOG) Fly for 9h 40m Arrive at 10:00am in Madrid (MAD)

Stay in Madrid for 8 nights

Thu Jul 17th 2025 LATAM Airlines · LA 1581 Depart at 12:10pm from Madrid (MAD) Fly for 10h 30m Arrive at 3:40pm in Bogotá (BOG)

Layover in Bogotá for 2h 37m

Thu Jul 17th 2025 Copa Airlines · CM 414 Depart at 6:17pm from Bogotá (BOG) Fly for 1h 47m Arrive at 8:04pm in Panama (PTY)

Book Flight
US$1726

3:20am - 11:30pm
Wed Jul 9th 2025

13h 10m
Panama (PTY) → Madrid (MAD)

1 Stop

5:30pm - 12:45am
Wed Jul 16th 2025

14h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 41 Depart at 3:20am from Panama (PTY) Fly for 1h 34m Arrive at 4:54am in Bogotá (BOG)

Layover in Bogotá for 2h 6m

Wed Jul 9th 2025 Avianca · AV 46 Depart at 7:00am from Bogotá (BOG) Fly for 9h 30m Arrive at 11:30pm in Madrid (MAD)

Stay in Madrid for 6 nights

Wed Jul 16th 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 2h 1m

Wed Jul 16th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight
US$1726

5:25pm - 2:05pm
Wed Jul 9th 2025

13h 40m
Panama (PTY) → Madrid (MAD)

1 Stop

5:30pm - 12:45am
Wed Jul 16th 2025

14h 15m
Madrid (MAD) → Panama (PTY)

1 Stop

Wed Jul 9th 2025 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)

Layover in Bogotá for 2h 40m

Wed Jul 9th 2025 Avianca · AV 10 Depart at 9:35pm from Bogotá (BOG) Fly for 9h 30m Arrive at 2:05pm in Madrid (MAD)

Stay in Madrid for 6 nights

Wed Jul 16th 2025 Avianca · AV 11 Depart at 5:30pm from Madrid (MAD) Fly for 10h 29m Arrive at 8:59pm in Bogotá (BOG)

Layover in Bogotá for 2h 1m

Wed Jul 16th 2025 Avianca · AV 40 Depart at 11:00pm from Bogotá (BOG) Fly for 1h 45m Arrive at 12:45am in Panama (PTY)

Book Flight

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality. It's designed for remote workers, backpackers, and people living abroad.

Read Sonaa's 7 Amazing Skyscanner Alternatives for Booking Travel

ANDY TRAVELS

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Read Josh's Ultimate Guide To Find Cheap One Way Flights

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Read Wesley's My Best Cheap Flight Hacks (Why Pay More?)

Cheap Flights from Panama City to Madrid (PTY to MAD)

Sarah Belizaire

John Ford

Roaming Sonaa

ANDY TRAVELS

Travel With Bender

Wesley Mergard

Latest Cheap Flight Searches

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Why I Built FlightList & Solved My Own Problem

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