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Wed Dec 10th 2025 Wingo airlines · P5 7039 Depart at 10:41am from Panama (BLB) Fly for 1h 29m Arrive at 12:10pm in Cali (CLO)
Layover in Cali for 7h 55m
Wed Dec 10th 2025 World2fly · 2W 2094 Depart at 8:05pm from Cali (CLO) Fly for 10h 0m Arrive at 12:05pm in Madrid (MAD)
Layover in Madrid for 9h 50m
Thu Dec 11th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Mon Dec 8th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Tue Dec 9th 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 24h 50m
Wed Dec 10th 2025 easyJet · U2 4492 Depart at 4:05pm from Prague (PRG) Fly for 1h 45m Arrive at 5:50pm in Lyon (LYS)
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Wed Nov 26th 2025 Wingo airlines · P5 7039 Depart at 10:41am from Panama (BLB) Fly for 1h 29m Arrive at 12:10pm in Cali (CLO)
Layover in Cali for 7h 55m
Wed Nov 26th 2025 World2fly · 2W 2094 Depart at 8:05pm from Cali (CLO) Fly for 10h 0m Arrive at 12:05pm in Madrid (MAD)
Layover in Madrid for 5h 35m
Thu Nov 27th 2025 easyJet · U2 4390 Depart at 5:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:30pm in Lyon (LYS)
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Thu Dec 4th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Dec 5th 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Dec 5th 2025 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Wed Dec 10th 2025 Wingo airlines · P5 7039 Depart at 10:41am from Panama (BLB) Fly for 1h 29m Arrive at 12:10pm in Cali (CLO)
Layover in Cali for 7h 55m
Wed Dec 10th 2025 World2fly · 2W 2094 Depart at 8:05pm from Cali (CLO) Fly for 10h 0m Arrive at 12:05pm in Madrid (MAD)
Layover in Madrid for 5h 35m
Thu Dec 11th 2025 easyJet · U2 4390 Depart at 5:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:30pm in Lyon (LYS)
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Thu Nov 20th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 23h 30m
Sat Nov 22nd 2025 Condor · DE 1404 Depart at 11:45am from Frankfurt (FRA) Fly for 4h 45m Arrive at 3:30pm in Las Palmas (LPA)
Layover in Las Palmas for 3h 20m
Sat Nov 22nd 2025 easyJet · U2 4400 Depart at 6:50pm from Las Palmas (LPA) Fly for 3h 55m Arrive at 11:45pm in Lyon (LYS)
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Tue Dec 9th 2025 Wingo airlines · P5 7043 Depart at 8:17am from Panama (BLB) Fly for 1h 17m Arrive at 9:34am in Medellín (MDE)
Layover in Medellín for 12h 16m
Tue Dec 9th 2025 Air Europa · UX 198 Depart at 9:50pm from Medellín (MDE) Fly for 9h 30m Arrive at 1:20pm in Madrid (MAD)
Layover in Madrid for 8h 35m
Wed Dec 10th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Fri Jan 23rd 2026 Copa Airlines · CM 240 Depart at 3:39pm from Panama (PTY) Fly for 3h 17m Arrive at 6:56pm in Miami (MIA)
Layover in Miami for 2h 49m
Fri Jan 23rd 2026 Level · LL 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 17h 5m
Sun Jan 25th 2026 Vueling · VY 1220 Depart at 6:10am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35am in Lyon (LYS)
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Sun Feb 15th 2026 Copa Airlines · CM 334 Depart at 10:25am from Panama (PTY) Fly for 3h 7m Arrive at 1:32pm in Miami (MIA)
Layover in Miami for 8h 13m
Sun Feb 15th 2026 Level · LL 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 17h 5m
Tue Feb 17th 2026 Vueling · VY 1220 Depart at 6:10am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35am in Lyon (LYS)
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Fri Jan 30th 2026 Copa Airlines · CM 240 Depart at 3:39pm from Panama (PTY) Fly for 3h 17m Arrive at 6:56pm in Miami (MIA)
Layover in Miami for 2h 49m
Fri Jan 30th 2026 Level · LL 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 4h 25m
Sat Jan 31st 2026 Vueling · VY 1222 Depart at 5:30pm from Barcelona (BCN) Fly for 1h 25m Arrive at 6:55pm in Lyon (LYS)
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Sun Feb 8th 2026 Copa Airlines · CM 485 Depart at 12:33pm from Panama (PTY) Fly for 3h 8m Arrive at 3:41pm in Miami (MIA)
Layover in Miami for 6h 4m
Sun Feb 8th 2026 Level · LL 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 2h 40m
Mon Feb 9th 2026 Vueling · VY 1222 Depart at 3:45pm from Barcelona (BCN) Fly for 1h 25m Arrive at 5:10pm in Lyon (LYS)
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Thu Nov 20th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Nov 21st 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Nov 21st 2025 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Fri Feb 6th 2026 Copa Airlines · CM 240 Depart at 3:39pm from Panama (PTY) Fly for 3h 17m Arrive at 6:56pm in Miami (MIA)
Layover in Miami for 2h 49m
Fri Feb 6th 2026 Level · LL 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 4h 30m
Sat Feb 7th 2026 Vueling · VY 1222 Depart at 5:35pm from Barcelona (BCN) Fly for 1h 25m Arrive at 7:00pm in Lyon (LYS)
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Mon Dec 1st 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 4h 30m
Tue Dec 2nd 2025 Lufthansa · LH 1078 Depart at 4:45pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 6:05pm in Lyon (LYS)
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Thu Nov 20th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 9h 50m
Fri Nov 21st 2025 Lufthansa · LH 1082 Depart at 10:05pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 11:25pm in Lyon (LYS)
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Mon Jan 26th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 1h 55m
Tue Jan 27th 2026 Condor · DE 4265 Depart at 2:10pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 3:30pm in Paris (CDG)
Layover in Paris for 5h 50m
Tue Jan 27th 2026 Air France · AF 7370 Depart at 9:20pm from Paris (CDG) Fly for 1h 10m Arrive at 10:30pm in Lyon (LYS)
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Thu Feb 5th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Feb 6th 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Feb 6th 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Thu Jan 22nd 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Jan 23rd 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Jan 23rd 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Wed Nov 26th 2025 Copa Airlines · CM 830 Depart at 3:47pm from Panama (PTY) Fly for 1h 42m Arrive at 5:29pm in Cali (CLO)
Layover in Cali for 2h 36m
Wed Nov 26th 2025 World2fly · 2W 2094 Depart at 8:05pm from Cali (CLO) Fly for 10h 0m Arrive at 12:05pm in Madrid (MAD)
Layover in Madrid for 5h 35m
Thu Nov 27th 2025 easyJet · U2 4390 Depart at 5:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:30pm in Lyon (LYS)
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Sat Mar 14th 2026 Copa Airlines · CM 460 Depart at 6:28pm from Panama (PTY) Fly for 1h 27m Arrive at 6:55pm in San José (SJO)
Layover in San José for 3h 5m
Sat Mar 14th 2026 Iberojet Airlines · E9 858 Depart at 10:00pm from San José (SJO) Fly for 10h 0m Arrive at 3:00pm in Madrid (MAD)
Layover in Madrid for 3h 0m
Sun Mar 15th 2026 easyJet · U2 4390 Depart at 6:00pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:50pm in Lyon (LYS)
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Mon Dec 8th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Tue Dec 9th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Tue Dec 9th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Wed Dec 10th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Sun Mar 8th 2026 Copa Airlines · CM 240 Depart at 3:39pm from Panama (PTY) Fly for 3h 16m Arrive at 7:55pm in Miami (MIA)
Layover in Miami for 2h 50m
Sun Mar 8th 2026 Level · LL 2630 Depart at 10:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 5h 0m
Mon Mar 9th 2026 Vueling · VY 1222 Depart at 6:05pm from Barcelona (BCN) Fly for 1h 25m Arrive at 7:30pm in Lyon (LYS)
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Tue Dec 9th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Wed Dec 10th 2025 easyJet · U2 4390 Depart at 4:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:30pm in Lyon (LYS)
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Sun Nov 30th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 2h 5m
Mon Dec 1st 2025 Air Europa · UX 7703 Depart at 3:10pm from Madrid (MAD) Fly for 1h 25m Arrive at 4:35pm in Barcelona (BCN)
Layover in Barcelona for 13h 35m
Tue Dec 2nd 2025 Vueling · VY 1220 Depart at 6:10am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35am in Lyon (LYS)
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Fri Feb 27th 2026 Copa Airlines · CM 240 Depart at 3:39pm from Panama (PTY) Fly for 3h 17m Arrive at 6:56pm in Miami (MIA)
Layover in Miami for 2h 49m
Fri Feb 27th 2026 Iberia Airlines · IB 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 4h 30m
Sat Feb 28th 2026 Vueling · VY 1222 Depart at 5:35pm from Barcelona (BCN) Fly for 1h 25m Arrive at 7:00pm in Lyon (LYS)
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Mon Dec 8th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 1h 55m
Tue Dec 9th 2025 Condor · DE 4265 Depart at 2:10pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 3:30pm in Paris (CDG)
Layover in Paris for 5h 50m
Tue Dec 9th 2025 Air France · AF 7370 Depart at 9:20pm from Paris (CDG) Fly for 1h 10m Arrive at 10:30pm in Lyon (LYS)
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Thu Dec 4th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 9h 50m
Fri Dec 5th 2025 Lufthansa · LH 1082 Depart at 10:05pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 11:25pm in Lyon (LYS)
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Wed Nov 19th 2025 Wingo airlines · P5 7039 Depart at 10:41am from Panama (BLB) Fly for 1h 29m Arrive at 12:10pm in Cali (CLO)
Layover in Cali for 7h 55m
Wed Nov 19th 2025 World2fly · 2W 2094 Depart at 8:05pm from Cali (CLO) Fly for 10h 0m Arrive at 12:05pm in Madrid (MAD)
Layover in Madrid for 5h 35m
Thu Nov 20th 2025 easyJet · U2 4390 Depart at 5:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:30pm in Lyon (LYS)
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Thu Feb 12th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Feb 13th 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Feb 13th 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Mon Dec 1st 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 1h 55m
Tue Dec 2nd 2025 Condor · DE 4265 Depart at 2:10pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 3:30pm in Paris (CDG)
Layover in Paris for 5h 50m
Tue Dec 2nd 2025 Air France · AF 7370 Depart at 9:20pm from Paris (CDG) Fly for 1h 10m Arrive at 10:30pm in Lyon (LYS)
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Fri Nov 28th 2025 Wingo airlines · P5 7047 Depart at 6:06pm from Panama (BLB) Fly for 1h 17m Arrive at 7:23pm in Medellín (MDE)
Layover in Medellín for 2h 42m
Fri Nov 28th 2025 Avianca · AV 16 Depart at 10:05pm from Medellín (MDE) Fly for 9h 45m Arrive at 1:50pm in Madrid (MAD)
Layover in Madrid for 8h 5m
Sat Nov 29th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Sun Jan 18th 2026 Copa Airlines · CM 240 Depart at 3:39pm from Panama (PTY) Fly for 3h 17m Arrive at 6:56pm in Miami (MIA)
Layover in Miami for 2h 49m
Sun Jan 18th 2026 Level · LL 2630 Depart at 9:45pm from Miami (MIA) Fly for 9h 20m Arrive at 1:05pm in Barcelona (BCN)
Layover in Barcelona for 2h 40m
Mon Jan 19th 2026 Vueling · VY 1222 Depart at 3:45pm from Barcelona (BCN) Fly for 1h 25m Arrive at 5:10pm in Lyon (LYS)
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Fri Nov 21st 2025 Wingo airlines · P5 7047 Depart at 6:06pm from Panama (BLB) Fly for 1h 17m Arrive at 7:23pm in Medellín (MDE)
Layover in Medellín for 2h 42m
Fri Nov 21st 2025 Avianca · AV 16 Depart at 10:05pm from Medellín (MDE) Fly for 9h 45m Arrive at 1:50pm in Madrid (MAD)
Layover in Madrid for 8h 5m
Sat Nov 22nd 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Mon Dec 1st 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Tue Dec 2nd 2025 Ryanair · FR 572 Depart at 4:40pm from Madrid (MAD) Fly for 1h 20m Arrive at 5:00pm in Porto (OPO)
Layover in Porto for 2h 20m
Tue Dec 2nd 2025 easyJet · U2 4432 Depart at 7:20pm from Porto (OPO) Fly for 2h 5m Arrive at 10:25pm in Lyon (LYS)
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Thu Jan 29th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Jan 30th 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Jan 30th 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Tue Nov 25th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 2h 5m
Wed Nov 26th 2025 Air Europa · UX 7703 Depart at 3:10pm from Madrid (MAD) Fly for 1h 25m Arrive at 4:35pm in Barcelona (BCN)
Layover in Barcelona for 13h 35m
Thu Nov 27th 2025 Vueling · VY 1220 Depart at 6:10am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35am in Lyon (LYS)
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Sat Dec 6th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Sun Dec 7th 2025 Volotea · V7 2661 Depart at 4:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Thu Nov 27th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 7h 50m
Fri Nov 28th 2025 Volotea · V7 2661 Depart at 8:55pm from Madrid (MAD) Fly for 1h 45m Arrive at 10:40pm in Lyon (LYS)
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Sat Feb 28th 2026 Copa Airlines · CM 460 Depart at 6:28pm from Panama (PTY) Fly for 1h 28m Arrive at 6:56pm in San José (SJO)
Layover in San José for 3h 4m
Sat Feb 28th 2026 Iberojet Airlines · E9 858 Depart at 10:00pm from San José (SJO) Fly for 10h 0m Arrive at 3:00pm in Madrid (MAD)
Layover in Madrid for 3h 0m
Sun Mar 1st 2026 easyJet · U2 4390 Depart at 6:00pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:50pm in Lyon (LYS)
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Wed Nov 26th 2025 Wingo airlines · P5 7039 Depart at 10:41am from Panama (BLB) Fly for 1h 29m Arrive at 12:10pm in Cali (CLO)
Layover in Cali for 7h 55m
Wed Nov 26th 2025 World2fly · 2W 2094 Depart at 8:05pm from Cali (CLO) Fly for 10h 0m Arrive at 12:05pm in Madrid (MAD)
Layover in Madrid for 4h 45m
Thu Nov 27th 2025 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Mon Dec 8th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 4h 30m
Tue Dec 9th 2025 Lufthansa · LH 1078 Depart at 4:45pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 6:05pm in Lyon (LYS)
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Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 9h 50m
Fri Nov 28th 2025 Lufthansa · LH 1082 Depart at 10:05pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 11:25pm in Lyon (LYS)
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Sat Mar 14th 2026 Copa Airlines · CM 391 Depart at 6:34pm from Panama (PTY) Fly for 1h 27m Arrive at 7:01pm in San José (SJO)
Layover in San José for 2h 59m
Sat Mar 14th 2026 Iberojet Airlines · E9 858 Depart at 10:00pm from San José (SJO) Fly for 10h 0m Arrive at 3:00pm in Madrid (MAD)
Layover in Madrid for 3h 0m
Sun Mar 15th 2026 easyJet · U2 4390 Depart at 6:00pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:50pm in Lyon (LYS)
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Thu Nov 27th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Nov 28th 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Nov 28th 2025 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Thu Dec 11th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Dec 12th 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Dec 12th 2025 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Thu Dec 25th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Dec 26th 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 3h 40m
Fri Dec 26th 2025 Volotea · V7 2039 Depart at 6:55pm from Prague (PRG) Fly for 1h 45m Arrive at 8:40pm in Lyon (LYS)
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Thu Mar 19th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Mar 20th 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Mar 20th 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Thu Apr 23rd 2026 Wingo airlines · P5 7073 Depart at 12:32pm from Panama (BLB) Fly for 1h 39m Arrive at 2:11pm in Bogotá (BOG)
Layover in Bogotá for 3h 19m
Thu Apr 23rd 2026 Iberia Airlines · IB 152 Depart at 5:30pm from Bogotá (BOG) Fly for 9h 30m Arrive at 10:00am in Madrid (MAD)
Layover in Madrid for 4h 0m
Fri Apr 24th 2026 easyJet · U2 4392 Depart at 2:00pm from Madrid (MAD) Fly for 1h 50m Arrive at 3:50pm in Lyon (LYS)
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Thu Mar 26th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Mar 27th 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Mar 27th 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Sat Dec 6th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 4h 55m
Sun Dec 7th 2025 easyJet · U2 4390 Depart at 6:00pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:50pm in Lyon (LYS)
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Thu Mar 12th 2026 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Mar 13th 2026 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Mar 13th 2026 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Tue May 5th 2026 Wingo airlines · P5 7073 Depart at 12:32pm from Panama (BLB) Fly for 1h 39m Arrive at 2:11pm in Bogotá (BOG)
Layover in Bogotá for 4h 29m
Tue May 5th 2026 Avianca · AV 182 Depart at 6:40pm from Bogotá (BOG) Fly for 9h 30m Arrive at 11:10am in Madrid (MAD)
Layover in Madrid for 2h 0m
Wed May 6th 2026 Volotea · V7 2661 Depart at 1:10pm from Madrid (MAD) Fly for 1h 45m Arrive at 2:55pm in Lyon (LYS)
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Tue Dec 2nd 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 4h 55m
Wed Dec 3rd 2025 TAP Portugal · TP 1017 Depart at 6:00pm from Madrid (MAD) Fly for 1h 25m Arrive at 6:25pm in Lisbon (LIS)
Layover in Lisbon for 2h 5m
Wed Dec 3rd 2025 TAP Portugal · TP 474 Depart at 8:30pm from Lisbon (LIS) Fly for 2h 25m Arrive at 11:55pm in Lyon (LYS)
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Fri Nov 21st 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Sat Nov 22nd 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Sun Nov 30th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 1h 50m
Mon Dec 1st 2025 Air Europa · UX 1155 Depart at 2:55pm from Madrid (MAD) Fly for 1h 20m Arrive at 3:15pm in Lisbon (LIS)
Layover in Lisbon for 2h 40m
Mon Dec 1st 2025 easyJet · U2 4428 Depart at 5:55pm from Lisbon (LIS) Fly for 2h 20m Arrive at 9:15pm in Lyon (LYS)
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Tue May 5th 2026 Avianca · AV 61 Depart at 5:25pm from Panama (PTY) Fly for 1h 30m Arrive at 6:55pm in Bogotá (BOG)
Layover in Bogotá for 2h 40m
Tue May 5th 2026 Avianca · AV 10 Depart at 9:35pm from Bogotá (BOG) Fly for 9h 30m Arrive at 2:05pm in Madrid (MAD)
Layover in Madrid for 2h 45m
Wed May 6th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Thu Nov 20th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 7h 50m
Fri Nov 21st 2025 Volotea · V7 2661 Depart at 8:55pm from Madrid (MAD) Fly for 1h 45m Arrive at 10:40pm in Lyon (LYS)
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Thu Nov 27th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 1h 55m
Fri Nov 28th 2025 Air Europa · UX 1015 Depart at 3:00pm from Madrid (MAD) Fly for 2h 25m Arrive at 4:25pm in London (LGW)
Layover in London for 3h 30m
Fri Nov 28th 2025 easyJet · U2 8436 Depart at 7:55pm from London (LGW) Fly for 1h 35m Arrive at 10:30pm in Lyon (LYS)
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Mon Nov 24th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 1h 55m
Tue Nov 25th 2025 Condor · DE 4265 Depart at 2:10pm from Frankfurt (FRA) Fly for 1h 20m Arrive at 3:30pm in Paris (CDG)
Layover in Paris for 5h 50m
Tue Nov 25th 2025 Air France · AF 7370 Depart at 9:20pm from Paris (CDG) Fly for 1h 10m Arrive at 10:30pm in Lyon (LYS)
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Sat Dec 6th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)
Layover in Istanbul for 3h 25m
Sun Dec 7th 2025 Turkish Airlines · TK 1851 Depart at 10:00pm from Istanbul (IST) Fly for 3h 50m Arrive at 11:50pm in Barcelona (BCN)
Layover in Barcelona for 6h 30m
Mon Dec 8th 2025 Iberia Airlines · IB 5248 Depart at 6:20am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:45am in Lyon (LYS)
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Sun Nov 23rd 2025 Air France · AF 475 Depart at 10:20pm from Panama (PTY) Fly for 10h 0m Arrive at 2:20pm in Paris (CDG)
Layover in Paris for 6h 45m
Mon Nov 24th 2025 Air France · AF 1448 Depart at 9:05pm from Paris (CDG) Fly for 1h 50m Arrive at 10:55pm in Barcelona (BCN)
Layover in Barcelona for 7h 15m
Tue Nov 25th 2025 Iberia Airlines · IB 5248 Depart at 6:10am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35am in Lyon (LYS)
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Mon May 4th 2026 Avianca · AV 8383 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)
Layover in Bogotá for 2h 35m
Mon May 4th 2026 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)
Layover in Madrid for 2h 25m
Tue May 5th 2026 Iberia Airlines · IB 1179 Depart at 10:05am from Madrid (MAD) Fly for 1h 50m Arrive at 11:55am in Lyon (LYS)
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Fri Nov 21st 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 4h 10m
Sat Nov 22nd 2025 Air Arabia Maroc · 3O 392 Depart at 5:15pm from Madrid (MAD) Fly for 1h 30m Arrive at 6:45pm in Tangier (TNG)
Layover in Tangier for 1h 50m
Sat Nov 22nd 2025 easyJet · U2 4406 Depart at 8:35pm from Tangier (TNG) Fly for 2h 20m Arrive at 10:55pm in Lyon (LYS)
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Fri Nov 28th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 4h 10m
Sat Nov 29th 2025 Air Arabia Maroc · 3O 392 Depart at 5:15pm from Madrid (MAD) Fly for 1h 30m Arrive at 6:45pm in Tangier (TNG)
Layover in Tangier for 1h 50m
Sat Nov 29th 2025 easyJet · U2 4406 Depart at 8:35pm from Tangier (TNG) Fly for 2h 20m Arrive at 10:55pm in Lyon (LYS)
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Sat Nov 22nd 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Sun Nov 23rd 2025 Volotea · V7 2661 Depart at 4:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Sat Feb 7th 2026 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Sun Feb 8th 2026 Volotea · V7 2661 Depart at 4:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Mon Dec 29th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Tue Dec 30th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Sun Nov 23rd 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Mon Nov 24th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Mon Nov 24th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Tue Nov 25th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Fri May 1st 2026 Avianca · AV 8383 Depart at 11:05am from Panama (PTY) Fly for 1h 30m Arrive at 12:35pm in Bogotá (BOG)
Layover in Bogotá for 2h 35m
Fri May 1st 2026 Avianca · AV 26 Depart at 3:10pm from Bogotá (BOG) Fly for 9h 30m Arrive at 7:40am in Madrid (MAD)
Layover in Madrid for 2h 25m
Sat May 2nd 2026 Iberia Airlines · IB 1179 Depart at 10:05am from Madrid (MAD) Fly for 1h 50m Arrive at 11:55am in Lyon (LYS)
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Tue Mar 3rd 2026 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Wed Mar 4th 2026 easyJet · U2 4390 Depart at 4:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:30pm in Lyon (LYS)
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Sun Dec 28th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 9h 40m
Mon Dec 29th 2025 Volotea · V7 2661 Depart at 10:45pm from Madrid (MAD) Fly for 1h 45m Arrive at 12:30am in Lyon (LYS)
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Sat Feb 14th 2026 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Sun Feb 15th 2026 Volotea · V7 2661 Depart at 4:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Thu Nov 27th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 4h 35m
Fri Nov 28th 2025 easyJet · U2 4390 Depart at 5:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 7:30pm in Lyon (LYS)
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Wed Dec 24th 2025 Air France · AF 475 Depart at 10:20pm from Panama (PTY) Fly for 10h 0m Arrive at 2:20pm in Paris (CDG)
Layover in Paris for 6h 45m
Thu Dec 25th 2025 Air France · AF 1448 Depart at 9:05pm from Paris (CDG) Fly for 1h 50m Arrive at 10:55pm in Barcelona (BCN)
Layover in Barcelona for 7h 35m
Fri Dec 26th 2025 Iberia Airlines · IB 5248 Depart at 6:30am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:55am in Lyon (LYS)
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Sat Nov 29th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)
Layover in Istanbul for 3h 25m
Sun Nov 30th 2025 Turkish Airlines · TK 1851 Depart at 10:00pm from Istanbul (IST) Fly for 3h 50m Arrive at 11:50pm in Barcelona (BCN)
Layover in Barcelona for 6h 30m
Mon Dec 1st 2025 Iberia Airlines · IB 5248 Depart at 6:20am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:45am in Lyon (LYS)
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Thu Dec 25th 2025 Condor · DE 2237 Depart at 7:05pm from Panama (PTY) Fly for 11h 10m Arrive at 12:15pm in Frankfurt (FRA)
Layover in Frankfurt for 2h 0m
Fri Dec 26th 2025 Condor · DE 4407 Depart at 2:15pm from Frankfurt (FRA) Fly for 1h 0m Arrive at 3:15pm in Prague (PRG)
Layover in Prague for 1h 25m
Fri Dec 26th 2025 easyJet · U2 4492 Depart at 4:40pm from Prague (PRG) Fly for 1h 45m Arrive at 6:25pm in Lyon (LYS)
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Wed Dec 24th 2025 Air France · AF 475 Depart at 10:20pm from Panama (PTY) Fly for 10h 0m Arrive at 2:20pm in Paris (CDG)
Layover in Paris for 1h 15m
Thu Dec 25th 2025 Air France · AF 1800 Depart at 3:35pm from Paris (CDG) Fly for 2h 5m Arrive at 5:40pm in Madrid (MAD)
Layover in Madrid for 4h 15m
Thu Dec 25th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Fri Nov 28th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Sat Nov 29th 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Mon Nov 24th 2025 Turkish Airlines · TK 904 Depart at 9:45pm from Panama (PTY) Fly for 12h 50m Arrive at 6:35pm in Istanbul (IST)
Layover in Istanbul for 3h 25m
Tue Nov 25th 2025 Turkish Airlines · TK 1851 Depart at 10:00pm from Istanbul (IST) Fly for 3h 50m Arrive at 11:50pm in Barcelona (BCN)
Layover in Barcelona for 6h 20m
Wed Nov 26th 2025 Iberia Airlines · IB 5248 Depart at 6:10am from Barcelona (BCN) Fly for 1h 25m Arrive at 7:35am in Lyon (LYS)
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Mon Dec 1st 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 8h 50m
Tue Dec 2nd 2025 Iberia Airlines · IB 1185 Depart at 9:55pm from Madrid (MAD) Fly for 1h 50m Arrive at 11:45pm in Lyon (LYS)
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Tue May 5th 2026 Air Europa · UX 56 Depart at 8:25pm from Panama (PTY) Fly for 9h 50m Arrive at 1:15pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Wed May 6th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Mon Dec 1st 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 45m
Tue Dec 2nd 2025 Vueling · VY 5778 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Mon Dec 29th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 4h 35m
Tue Dec 30th 2025 Volotea · V7 2661 Depart at 5:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 7:25pm in Lyon (LYS)
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Tue Dec 30th 2025 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 35m Arrive at 1:05pm in Madrid (MAD)
Layover in Madrid for 3h 35m
Wed Dec 31st 2025 easyJet · U2 4390 Depart at 4:40pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:30pm in Lyon (LYS)
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Wed Feb 4th 2026 Iberia Airlines · IB 258 Depart at 6:20pm from Panama (PTY) Fly for 10h 5m Arrive at 10:25am in Madrid (MAD)
Layover in Madrid for 1h 0m
Thu Feb 5th 2026 Iberia Airlines · IB 531 Depart at 11:25am from Madrid (MAD) Fly for 1h 25m Arrive at 11:50am in Lisbon (LIS)
Layover in Lisbon for 2h 20m
Thu Feb 5th 2026 TAP Portugal · TP 472 Depart at 2:10pm from Lisbon (LIS) Fly for 2h 25m Arrive at 5:35pm in Lyon (LYS)
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Sat Mar 28th 2026 Air Europa · UX 56 Depart at 9:30pm from Panama (PTY) Fly for 9h 25m Arrive at 1:55pm in Madrid (MAD)
Layover in Madrid for 2h 55m
Sun Mar 29th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Fri Apr 24th 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Sat Apr 25th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Wed Apr 22nd 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Thu Apr 23rd 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Fri May 8th 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Sat May 9th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Tue Nov 18th 2025 Turkish Airlines · TK 900 Depart at 6:45pm from Panama (PTY) Fly for 12h 45m Arrive at 3:30pm in Istanbul (IST)
Layover in Istanbul for 16h 45m
Thu Nov 20th 2025 Turkish Airlines · TK 1807 Depart at 8:15am from Istanbul (IST) Fly for 3h 20m Arrive at 9:35am in Lyon (LYS)
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Sun May 10th 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Mon May 11th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Wed Apr 1st 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Thu Apr 2nd 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Sun Mar 29th 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Mon Mar 30th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Sun May 3rd 2026 Copa Airlines · CM 5880 Depart at 9:30pm from Panama (PTY) Fly for 9h 50m Arrive at 2:20pm in Madrid (MAD)
Layover in Madrid for 2h 30m
Mon May 4th 2026 Iberia Airlines · IB 1183 Depart at 4:50pm from Madrid (MAD) Fly for 1h 50m Arrive at 6:40pm in Lyon (LYS)
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Sat Dec 27th 2025 Iberia Airlines · IB 258 Depart at 6:20pm from Panama (PTY) Fly for 10h 5m Arrive at 10:25am in Madrid (MAD)
Layover in Madrid for 2h 15m
Sun Dec 28th 2025 Volotea · V7 2661 Depart at 12:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 2:25pm in Lyon (LYS)
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Sat Dec 20th 2025 Iberia Airlines · IB 258 Depart at 6:20pm from Panama (PTY) Fly for 10h 5m Arrive at 10:25am in Madrid (MAD)
Layover in Madrid for 2h 15m
Sun Dec 21st 2025 Volotea · V7 2661 Depart at 12:40pm from Madrid (MAD) Fly for 1h 45m Arrive at 2:25pm in Lyon (LYS)
