Cheap Flights from Orlando to Rio Negro (MCO to MDE)

Discover more affordable routes and cheaper dates from Orlando to Rio Negro (MCO to MDE) within a date range.

⭐ Search by country or region to discover more affordable routes, like Netherlands → Italy or Europe → South East Asia.

Results Quantity

Cabin Bags

Checked Bags

Max Budget

US$

Max Duration

Hours

Max Layover

Hours

Departure Time

Connections

Select Airlines

Loading…

US$194

4:06pm - 10:40pm
Fri Nov 28th 2025

6h 34m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Fri Nov 28th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$194

4:06pm - 11:59pm
Fri Nov 28th 2025

7h 53m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 2h 50m

Fri Nov 28th 2025 LATAM Airlines · LA 4034 Depart at 11:00pm from Bogotá (BOG) Fly for 0h 59m Arrive at 11:59pm in Medellín (MDE)
US$194

4:06pm - 2:05am
Fri Nov 28th 2025

9h 59m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 4h 55m

Sat Nov 29th 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$202

1:55pm - 11:17pm
Fri Nov 28th 2025

33h 22m
Orlando (MCO) → Medellín (MDE)

2 Stops

Fri Nov 28th 2025 Avianca · AV 29 Depart at 1:55pm from Orlando (MCO) Fly for 3h 59m Arrive at 5:54pm in Bogotá (BOG)

Layover in Bogotá for 3h 29m

Fri Nov 28th 2025 Avianca · AV 9215 Depart at 9:23pm from Bogotá (BOG) Fly for 1h 11m Arrive at 10:34pm in Cali (CLO)

Layover in Cali for 23h 49m

Sat Nov 29th 2025 JetSMART · JA 5475 Depart at 10:23pm from Cali (CLO) Fly for 0h 54m Arrive at 11:17pm in Medellín (MDE)
US$213

1:43pm - 8:07pm
Fri Nov 28th 2025

6h 24m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Copa Airlines · CM 479 Depart at 1:43pm from Orlando (MCO) Fly for 3h 29m Arrive at 5:12pm in Panama (PTY)

Layover in Panama for 1h 31m

Fri Nov 28th 2025 Copa Airlines · CM 163 Depart at 6:43pm from Panama (PTY) Fly for 1h 24m Arrive at 8:07pm in Medellín (MDE)
US$213

1:43pm - 8:07pm
Sun Nov 30th 2025

6h 24m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Copa Airlines · CM 479 Depart at 1:43pm from Orlando (MCO) Fly for 3h 29m Arrive at 5:12pm in Panama (PTY)

Layover in Panama for 1h 31m

Sun Nov 30th 2025 Copa Airlines · CM 163 Depart at 6:43pm from Panama (PTY) Fly for 1h 24m Arrive at 8:07pm in Medellín (MDE)
US$213

7:13am - 7:56pm
Sun Nov 30th 2025

12h 43m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 7h 49m

Sun Nov 30th 2025 Copa Airlines · CM 208 Depart at 6:31pm from Panama (PTY) Fly for 1h 25m Arrive at 7:56pm in Medellín (MDE)
US$213

1:43pm - 10:33am
Thu Nov 27th 2025

20h 50m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Copa Airlines · CM 479 Depart at 1:43pm from Orlando (MCO) Fly for 3h 29m Arrive at 5:12pm in Panama (PTY)

Layover in Panama for 15h 57m

Fri Nov 28th 2025 Copa Airlines · CM 855 Depart at 9:09am from Panama (PTY) Fly for 1h 24m Arrive at 10:33am in Medellín (MDE)
US$214

1:43pm - 7:56pm
Fri Nov 28th 2025

6h 13m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Copa Airlines · CM 479 Depart at 1:43pm from Orlando (MCO) Fly for 3h 29m Arrive at 5:12pm in Panama (PTY)

Layover in Panama for 1h 19m

Fri Nov 28th 2025 Copa Airlines · CM 208 Depart at 6:31pm from Panama (PTY) Fly for 1h 25m Arrive at 7:56pm in Medellín (MDE)
US$219

3:55pm - 6:05am
Sun Nov 30th 2025

14h 10m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sun Nov 30th 2025 Copa Airlines · CM 459 Depart at 3:55pm from Orlando (MCO) Fly for 3h 29m Arrive at 7:24pm in Panama (PTY)

Layover in Panama for 1h 21m

Sun Nov 30th 2025 Copa Airlines · CM 860 Depart at 8:45pm from Panama (PTY) Fly for 1h 38m Arrive at 10:23pm in Bogotá (BOG)

Layover in Bogotá for 6h 37m

Mon Dec 1st 2025 JetSMART · JA 5120 Depart at 5:00am from Bogotá (BOG) Fly for 1h 5m Arrive at 6:05am in Medellín (MDE)
US$219

2:26pm - 6:59am
Sat Nov 29th 2025

16h 33m
Orlando (MCO) → Medellín (EOH)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 868 Depart at 2:26pm from Orlando (MCO) Fly for 3h 30m Arrive at 5:56pm in Panama (PTY)

Layover in Panama for 4h 30m

Sat Nov 29th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 44m

Sun Nov 30th 2025 SATENA · 9R 8604 Depart at 5:50am from Bogotá (BOG) Fly for 1h 9m Arrive at 6:59am in Medellín (EOH)
US$220

2:40pm - 10:33pm
Fri Nov 28th 2025

7h 53m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 53m

Fri Nov 28th 2025 JetSMART · JA 5118 Depart at 9:28pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:33pm in Medellín (MDE)
US$220

1:55pm - 10:33pm
Fri Nov 28th 2025

8h 38m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 29 Depart at 1:55pm from Orlando (MCO) Fly for 3h 59m Arrive at 5:54pm in Bogotá (BOG)

Layover in Bogotá for 3h 34m

Fri Nov 28th 2025 JetSMART · JA 5118 Depart at 9:28pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:33pm in Medellín (MDE)
US$221

4:06pm - 10:40pm
Sun Nov 30th 2025

6h 34m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Sun Nov 30th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$221

4:06pm - 11:59pm
Thu Nov 27th 2025

7h 53m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 2h 50m

Thu Nov 27th 2025 LATAM Airlines · LA 4034 Depart at 11:00pm from Bogotá (BOG) Fly for 0h 59m Arrive at 11:59pm in Medellín (MDE)
US$221

2:40pm - 11:44pm
Fri Nov 28th 2025

9h 4m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 4h 6m

Fri Nov 28th 2025 Wingo airlines · P5 7290 Depart at 10:41pm from Bogotá (BOG) Fly for 1h 3m Arrive at 11:44pm in Medellín (MDE)
US$221

1:55pm - 11:44pm
Fri Nov 28th 2025

9h 49m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 29 Depart at 1:55pm from Orlando (MCO) Fly for 3h 59m Arrive at 5:54pm in Bogotá (BOG)

Layover in Bogotá for 4h 47m

Fri Nov 28th 2025 Wingo airlines · P5 7290 Depart at 10:41pm from Bogotá (BOG) Fly for 1h 3m Arrive at 11:44pm in Medellín (MDE)
US$221

4:06pm - 2:05am
Sun Nov 30th 2025

9h 59m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 4h 55m

Mon Dec 1st 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$221

4:06pm - 2:05am
Thu Nov 27th 2025

9h 59m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 4h 55m

Fri Nov 28th 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$223

2:40pm - 6:30am
Fri Nov 28th 2025

15h 50m
Orlando (MCO) → Medellín (EOH)

1 Stop

Fri Nov 28th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 10h 45m

Sat Nov 29th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$223

2:26pm - 11:50am
Sat Nov 29th 2025

21h 24m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 868 Depart at 2:26pm from Orlando (MCO) Fly for 3h 30m Arrive at 5:56pm in Panama (PTY)

Layover in Panama for 4h 30m

Sat Nov 29th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 10h 39m

Sun Nov 30th 2025 JetSMART · JA 5112 Depart at 10:45am from Bogotá (BOG) Fly for 1h 5m Arrive at 11:50am in Medellín (MDE)
US$225

3:25pm - 10:51pm
Thu Nov 27th 2025

7h 26m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Copa Airlines · CM 868 Depart at 3:25pm from Orlando (MCO) Fly for 3h 28m Arrive at 6:53pm in Panama (PTY)

Layover in Panama for 2h 33m

Thu Nov 27th 2025 Copa Airlines · CM 155 Depart at 9:26pm from Panama (PTY) Fly for 1h 25m Arrive at 10:51pm in Medellín (MDE)
US$225

2:26pm - 9:02am
Sat Nov 29th 2025

18h 36m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 868 Depart at 2:26pm from Orlando (MCO) Fly for 3h 30m Arrive at 5:56pm in Panama (PTY)

Layover in Panama for 4h 30m

Sat Nov 29th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 7h 54m

Sun Nov 30th 2025 Wingo airlines · P5 7270 Depart at 8:00am from Bogotá (BOG) Fly for 1h 2m Arrive at 9:02am in Medellín (MDE)
US$226

3:25pm - 5:45am
Thu Nov 27th 2025

14h 20m
Orlando (MCO) → Medellín (MDE)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 868 Depart at 3:25pm from Orlando (MCO) Fly for 3h 28m Arrive at 6:53pm in Panama (PTY)

Layover in Panama for 1h 52m

Thu Nov 27th 2025 Copa Airlines · CM 860 Depart at 8:45pm from Panama (PTY) Fly for 1h 38m Arrive at 10:23pm in Bogotá (BOG)

Layover in Bogotá for 6h 17m

Fri Nov 28th 2025 JetSMART · JA 5110 Depart at 4:40am from Bogotá (BOG) Fly for 1h 5m Arrive at 5:45am in Medellín (MDE)
US$227

2:40pm - 10:35pm
Thu Nov 27th 2025

7h 55m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 55m

Thu Nov 27th 2025 JetSMART · JA 5124 Depart at 9:30pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:35pm in Medellín (MDE)
US$229

2:40pm - 5:45am
Thu Nov 27th 2025

15h 5m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 10h 5m

Fri Nov 28th 2025 JetSMART · JA 5110 Depart at 4:40am from Bogotá (BOG) Fly for 1h 5m Arrive at 5:45am in Medellín (MDE)
US$232

2:40pm - 10:40pm
Fri Nov 28th 2025

8h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 3h 5m

Fri Nov 28th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$232

1:55pm - 10:40pm
Fri Nov 28th 2025

8h 45m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 29 Depart at 1:55pm from Orlando (MCO) Fly for 3h 59m Arrive at 5:54pm in Bogotá (BOG)

Layover in Bogotá for 3h 46m

Fri Nov 28th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$232

2:40pm - 11:59pm
Fri Nov 28th 2025

9h 19m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 4h 25m

Fri Nov 28th 2025 LATAM Airlines · LA 4034 Depart at 11:00pm from Bogotá (BOG) Fly for 0h 59m Arrive at 11:59pm in Medellín (MDE)
US$233

2:26pm - 6:35am
Sat Nov 29th 2025

16h 9m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 868 Depart at 2:26pm from Orlando (MCO) Fly for 3h 30m Arrive at 5:56pm in Panama (PTY)

Layover in Panama for 4h 30m

Sat Nov 29th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 24m

Sun Nov 30th 2025 JetSMART · JA 5118 Depart at 5:30am from Bogotá (BOG) Fly for 1h 5m Arrive at 6:35am in Medellín (MDE)
US$234

3:55pm - 6:30am
Sun Nov 30th 2025

14h 35m
Orlando (MCO) → Medellín (EOH)

2 Stops

Sun Nov 30th 2025 Copa Airlines · CM 459 Depart at 3:55pm from Orlando (MCO) Fly for 3h 29m Arrive at 7:24pm in Panama (PTY)

Layover in Panama for 1h 21m

Sun Nov 30th 2025 Copa Airlines · CM 860 Depart at 8:45pm from Panama (PTY) Fly for 1h 38m Arrive at 10:23pm in Bogotá (BOG)

Layover in Bogotá for 6h 57m

Mon Dec 1st 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$234

3:25pm - 9:40am
Thu Nov 27th 2025

18h 15m
Orlando (MCO) → Medellín (EOH)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 868 Depart at 3:25pm from Orlando (MCO) Fly for 3h 28m Arrive at 6:53pm in Panama (PTY)

Layover in Panama for 1h 52m

Thu Nov 27th 2025 Copa Airlines · CM 860 Depart at 8:45pm from Panama (PTY) Fly for 1h 38m Arrive at 10:23pm in Bogotá (BOG)

Layover in Bogotá for 10h 7m

Fri Nov 28th 2025 Clic · VE 9106 Depart at 8:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 9:40am in Medellín (EOH)
US$235

2:40pm - 11:07pm
Thu Nov 27th 2025

8h 27m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 3h 29m

Thu Nov 27th 2025 Wingo airlines · P5 7290 Depart at 10:04pm from Bogotá (BOG) Fly for 1h 3m Arrive at 11:07pm in Medellín (MDE)
US$237

2:40pm - 9:40am
Thu Nov 27th 2025

19h 0m
Orlando (MCO) → Medellín (EOH)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 13h 55m

Fri Nov 28th 2025 Clic · VE 9106 Depart at 8:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 9:40am in Medellín (EOH)
US$238

7:13am - 11:24pm
Sat Nov 29th 2025

16h 11m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 4h 43m

Sat Nov 29th 2025 Copa Airlines · CM 413 Depart at 3:25pm from Panama (PTY) Fly for 1h 40m Arrive at 5:05pm in Bogotá (BOG)

Layover in Bogotá for 5h 16m

Sat Nov 29th 2025 Wingo airlines · P5 7290 Depart at 10:21pm from Bogotá (BOG) Fly for 1h 3m Arrive at 11:24pm in Medellín (MDE)
US$239

4:06pm - 10:40pm
Sat Nov 29th 2025

6h 34m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Sat Nov 29th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$239

4:06pm - 10:40pm
Thu Nov 27th 2025

6h 34m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 30m

Thu Nov 27th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$244

4:58pm - 6:05am
Sun Nov 30th 2025

13h 7m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sun Nov 30th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 1h 59m

Sun Nov 30th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 4h 54m

Mon Dec 1st 2025 JetSMART · JA 5120 Depart at 5:00am from Bogotá (BOG) Fly for 1h 5m Arrive at 6:05am in Medellín (MDE)
US$246

2:40pm - 2:05am
Thu Nov 27th 2025

11h 25m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 6h 30m

Fri Nov 28th 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$246

2:26pm - 6:14am
Sat Nov 29th 2025

15h 48m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 868 Depart at 2:26pm from Orlando (MCO) Fly for 3h 30m Arrive at 5:56pm in Panama (PTY)

Layover in Panama for 4h 30m

Sat Nov 29th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 9m

Sun Nov 30th 2025 Avianca · AV 9252 Depart at 5:15am from Bogotá (BOG) Fly for 0h 59m Arrive at 6:14am in Medellín (MDE)
US$247

3:25pm - 6:30am
Thu Nov 27th 2025

15h 5m
Orlando (MCO) → Medellín (EOH)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 868 Depart at 3:25pm from Orlando (MCO) Fly for 3h 28m Arrive at 6:53pm in Panama (PTY)

Layover in Panama for 1h 52m

Thu Nov 27th 2025 Copa Airlines · CM 860 Depart at 8:45pm from Panama (PTY) Fly for 1h 38m Arrive at 10:23pm in Bogotá (BOG)

Layover in Bogotá for 6h 57m

Fri Nov 28th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$249

10:39am - 11:24pm
Sat Nov 29th 2025

12h 45m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 239 Depart at 10:39am from Orlando (MCO) Fly for 3h 29m Arrive at 2:08pm in Panama (PTY)

Layover in Panama for 1h 17m

Sat Nov 29th 2025 Copa Airlines · CM 413 Depart at 3:25pm from Panama (PTY) Fly for 1h 40m Arrive at 5:05pm in Bogotá (BOG)

Layover in Bogotá for 5h 16m

Sat Nov 29th 2025 Wingo airlines · P5 7290 Depart at 10:21pm from Bogotá (BOG) Fly for 1h 3m Arrive at 11:24pm in Medellín (MDE)
US$250

2:40pm - 6:30am
Thu Nov 27th 2025

15h 50m
Orlando (MCO) → Medellín (EOH)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 10h 45m

Fri Nov 28th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$251

2:40pm - 10:29pm
Fri Nov 28th 2025

7h 49m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Fri Nov 28th 2025 Avianca · AV 9344 Depart at 9:24pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:29pm in Medellín (MDE)
US$251

2:40pm - 10:40pm
Thu Nov 27th 2025

8h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 3h 5m

Thu Nov 27th 2025 LATAM Airlines · LA 4032 Depart at 9:40pm from Bogotá (BOG) Fly for 1h 0m Arrive at 10:40pm in Medellín (MDE)
US$251

2:40pm - 11:59pm
Thu Nov 27th 2025

9h 19m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 4h 25m

Thu Nov 27th 2025 LATAM Airlines · LA 4034 Depart at 11:00pm from Bogotá (BOG) Fly for 0h 59m Arrive at 11:59pm in Medellín (MDE)
US$258

4:58pm - 6:30am
Sun Nov 30th 2025

13h 32m
Orlando (MCO) → Medellín (EOH)

2 Stops

Sun Nov 30th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 1h 59m

Sun Nov 30th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 14m

Mon Dec 1st 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$267

1:43pm - 7:56pm
Sun Nov 30th 2025

6h 13m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Copa Airlines · CM 479 Depart at 1:43pm from Orlando (MCO) Fly for 3h 29m Arrive at 5:12pm in Panama (PTY)

Layover in Panama for 1h 19m

Sun Nov 30th 2025 Copa Airlines · CM 208 Depart at 6:31pm from Panama (PTY) Fly for 1h 25m Arrive at 7:56pm in Medellín (MDE)
US$267

7:13am - 2:13pm
Sun Nov 30th 2025

7h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 2h 6m

Sun Nov 30th 2025 Copa Airlines · CM 502 Depart at 12:48pm from Panama (PTY) Fly for 1h 25m Arrive at 2:13pm in Medellín (MDE)
US$267

7:13am - 2:13pm
Sat Nov 29th 2025

7h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 2h 6m

Sat Nov 29th 2025 Copa Airlines · CM 502 Depart at 12:48pm from Panama (PTY) Fly for 1h 25m Arrive at 2:13pm in Medellín (MDE)
US$277

12:41pm - 7:20pm
Thu Nov 27th 2025

6h 39m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 LATAM Airlines · LA 4409 Depart at 12:41pm from Orlando (MCO) Fly for 4h 4m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Thu Nov 27th 2025 LATAM Airlines · LA 4030 Depart at 6:20pm from Bogotá (BOG) Fly for 1h 0m Arrive at 7:20pm in Medellín (MDE)
US$283

2:26pm - 7:56pm
Sat Nov 29th 2025

5h 30m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 Copa Airlines · CM 868 Depart at 2:26pm from Orlando (MCO) Fly for 3h 30m Arrive at 5:56pm in Panama (PTY)

Layover in Panama for 0h 35m

Sat Nov 29th 2025 Copa Airlines · CM 208 Depart at 6:31pm from Panama (PTY) Fly for 1h 25m Arrive at 7:56pm in Medellín (MDE)
US$284

4:58pm - 5:45am
Thu Nov 27th 2025

12h 47m
Orlando (MCO) → Medellín (MDE)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 1h 59m

Thu Nov 27th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 4h 34m

Fri Nov 28th 2025 JetSMART · JA 5110 Depart at 4:40am from Bogotá (BOG) Fly for 1h 5m Arrive at 5:45am in Medellín (MDE)
US$286

4:58pm - 9:45am
Fri Nov 28th 2025

16h 47m
Orlando (MCO) → Medellín (MDE)

2 Stops

Fri Nov 28th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Fri Nov 28th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 9h 39m

Sat Nov 29th 2025 JetSMART · JA 5122 Depart at 8:40am from Bogotá (BOG) Fly for 1h 5m Arrive at 9:45am in Medellín (MDE)
US$287

10:39am - 5:02pm
Sat Nov 29th 2025

6h 23m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 Copa Airlines · CM 239 Depart at 10:39am from Orlando (MCO) Fly for 3h 29m Arrive at 2:08pm in Panama (PTY)

Layover in Panama for 1h 29m

Sat Nov 29th 2025 Copa Airlines · CM 156 Depart at 3:37pm from Panama (PTY) Fly for 1h 25m Arrive at 5:02pm in Medellín (MDE)
US$287

7:13am - 2:13pm
Thu Nov 27th 2025

7h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 2h 6m

Thu Nov 27th 2025 Copa Airlines · CM 502 Depart at 12:48pm from Panama (PTY) Fly for 1h 25m Arrive at 2:13pm in Medellín (MDE)
US$288

1:43pm - 7:56pm
Thu Nov 27th 2025

6h 13m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Copa Airlines · CM 479 Depart at 1:43pm from Orlando (MCO) Fly for 3h 29m Arrive at 5:12pm in Panama (PTY)

Layover in Panama for 1h 19m

Thu Nov 27th 2025 Copa Airlines · CM 208 Depart at 6:31pm from Panama (PTY) Fly for 1h 25m Arrive at 7:56pm in Medellín (MDE)
US$288

10:39am - 5:02pm
Thu Nov 27th 2025

6h 23m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Copa Airlines · CM 239 Depart at 10:39am from Orlando (MCO) Fly for 3h 29m Arrive at 2:08pm in Panama (PTY)

Layover in Panama for 1h 29m

Thu Nov 27th 2025 Copa Airlines · CM 156 Depart at 3:37pm from Panama (PTY) Fly for 1h 25m Arrive at 5:02pm in Medellín (MDE)
US$288

10:39am - 5:02pm
Sun Nov 30th 2025

6h 23m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Copa Airlines · CM 239 Depart at 10:39am from Orlando (MCO) Fly for 3h 29m Arrive at 2:08pm in Panama (PTY)

Layover in Panama for 1h 29m

Sun Nov 30th 2025 Copa Airlines · CM 156 Depart at 3:37pm from Panama (PTY) Fly for 1h 25m Arrive at 5:02pm in Medellín (MDE)
US$288

7:13am - 2:13pm
Fri Nov 28th 2025

7h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 2h 6m

Fri Nov 28th 2025 Copa Airlines · CM 502 Depart at 12:48pm from Panama (PTY) Fly for 1h 25m Arrive at 2:13pm in Medellín (MDE)
US$289

4:58pm - 6:05am
Fri Nov 28th 2025

13h 7m
Orlando (MCO) → Medellín (MDE)

2 Stops

Fri Nov 28th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Fri Nov 28th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 5h 59m

Sat Nov 29th 2025 JetSMART · JA 5110 Depart at 5:00am from Bogotá (BOG) Fly for 1h 5m Arrive at 6:05am in Medellín (MDE)
US$289

4:06pm - 6:30am
Fri Nov 28th 2025

14h 24m
Orlando (MCO) → Medellín (EOH)

1 Stop

Fri Nov 28th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 9h 10m

Sat Nov 29th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$292

1:55pm - 9:16pm
Sun Nov 30th 2025

7h 21m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Avianca · AV 29 Depart at 1:55pm from Orlando (MCO) Fly for 3h 59m Arrive at 5:54pm in Bogotá (BOG)

Layover in Bogotá for 2h 26m

Sun Nov 30th 2025 Avianca · AV 9356 Depart at 8:20pm from Bogotá (BOG) Fly for 0h 56m Arrive at 9:16pm in Medellín (MDE)
US$292

7:13am - 5:02pm
Sat Nov 29th 2025

9h 49m
Orlando (MCO) → Medellín (EOH)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 1h 26m

Sat Nov 29th 2025 Copa Airlines · CM 415 Depart at 12:08pm from Panama (PTY) Fly for 1h 40m Arrive at 1:48pm in Bogotá (BOG)

Layover in Bogotá for 2h 5m

Sat Nov 29th 2025 SATENA · 9R 8616 Depart at 3:53pm from Bogotá (BOG) Fly for 1h 9m Arrive at 5:02pm in Medellín (EOH)
US$292

4:58pm - 6:30am
Fri Nov 28th 2025

13h 32m
Orlando (MCO) → Medellín (EOH)

2 Stops

Fri Nov 28th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Fri Nov 28th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 6h 19m

Sat Nov 29th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$292

4:58pm - 9:40am
Thu Nov 27th 2025

16h 42m
Orlando (MCO) → Medellín (EOH)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 1h 59m

Thu Nov 27th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 8h 24m

Fri Nov 28th 2025 Clic · VE 9106 Depart at 8:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 9:40am in Medellín (EOH)
US$293

4:58pm - 5:50am
Fri Nov 28th 2025

12h 52m
Orlando (MCO) → Medellín (MDE)

2 Stops

Fri Nov 28th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Fri Nov 28th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 5h 44m

Sat Nov 29th 2025 JetSMART · JA 5112 Depart at 4:45am from Bogotá (BOG) Fly for 1h 5m Arrive at 5:50am in Medellín (MDE)
US$305

4:58pm - 6:30am
Thu Nov 27th 2025

13h 32m
Orlando (MCO) → Medellín (EOH)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 1h 59m

Thu Nov 27th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 14m

Fri Nov 28th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$306

4:58pm - 2:05am
Sun Nov 30th 2025

9h 7m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sun Nov 30th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Sun Nov 30th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 2h 4m

Mon Dec 1st 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$308

4:58pm - 2:05am
Fri Nov 28th 2025

9h 7m
Orlando (MCO) → Medellín (MDE)

2 Stops

Fri Nov 28th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Fri Nov 28th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 2h 4m

Sat Nov 29th 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$308

4:06pm - 6:59am
Sat Nov 29th 2025

14h 53m
Orlando (MCO) → Medellín (EOH)

1 Stop

Sat Nov 29th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 9h 40m

Sun Nov 30th 2025 SATENA · 9R 8604 Depart at 5:50am from Bogotá (BOG) Fly for 1h 9m Arrive at 6:59am in Medellín (EOH)
US$313

5:05pm - 10:05am
Sun Nov 30th 2025

17h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Volaris · Y4 781 Depart at 5:05pm from Orlando (MCO) Fly for 3h 40m Arrive at 7:45pm in Mexico City (MEX)

Layover in Mexico City for 9h 15m

Mon Dec 1st 2025 Avianca · AV 235 Depart at 5:00am from Mexico City (MEX) Fly for 4h 5m Arrive at 10:05am in Medellín (MDE)
US$313

5:05pm - 10:05am
Fri Nov 28th 2025

17h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Volaris · Y4 781 Depart at 5:05pm from Orlando (MCO) Fly for 3h 40m Arrive at 7:45pm in Mexico City (MEX)

Layover in Mexico City for 9h 15m

Sat Nov 29th 2025 Avianca · AV 235 Depart at 5:00am from Mexico City (MEX) Fly for 4h 5m Arrive at 10:05am in Medellín (MDE)
US$314

10:39am - 5:02pm
Fri Nov 28th 2025

6h 23m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Copa Airlines · CM 239 Depart at 10:39am from Orlando (MCO) Fly for 3h 29m Arrive at 2:08pm in Panama (PTY)

Layover in Panama for 1h 29m

Fri Nov 28th 2025 Copa Airlines · CM 156 Depart at 3:37pm from Panama (PTY) Fly for 1h 25m Arrive at 5:02pm in Medellín (MDE)
US$317

2:40pm - 8:48pm
Thu Nov 27th 2025

6h 8m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 1h 17m

Thu Nov 27th 2025 Avianca · AV 9312 Depart at 7:52pm from Bogotá (BOG) Fly for 0h 56m Arrive at 8:48pm in Medellín (MDE)
US$319

2:40pm - 9:38pm
Thu Nov 27th 2025

6h 58m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 7m

Thu Nov 27th 2025 Avianca · AV 9268 Depart at 8:42pm from Bogotá (BOG) Fly for 0h 56m Arrive at 9:38pm in Medellín (MDE)
US$319

2:40pm - 9:55pm
Thu Nov 27th 2025

7h 15m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 24m

Thu Nov 27th 2025 Avianca · AV 9250 Depart at 8:59pm from Bogotá (BOG) Fly for 0h 56m Arrive at 9:55pm in Medellín (MDE)
US$319

2:40pm - 10:29pm
Thu Nov 27th 2025

7h 49m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 2h 49m

Thu Nov 27th 2025 Avianca · AV 9344 Depart at 9:24pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:29pm in Medellín (MDE)
US$319

2:40pm - 10:49pm
Thu Nov 27th 2025

8h 9m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 3h 9m

Thu Nov 27th 2025 Avianca · AV 8458 Depart at 9:44pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:49pm in Medellín (MDE)
US$319

2:40pm - 11:22pm
Thu Nov 27th 2025

8h 42m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 3h 45m

Thu Nov 27th 2025 Avianca · AV 8449 Depart at 10:20pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:22pm in Medellín (MDE)
US$319

2:40pm - 11:44pm
Thu Nov 27th 2025

9h 4m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 4h 10m

Thu Nov 27th 2025 Avianca · AV 9342 Depart at 10:45pm from Bogotá (BOG) Fly for 0h 59m Arrive at 11:44pm in Medellín (MDE)
US$320

12:41pm - 7:20pm
Fri Nov 28th 2025

6h 39m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 LATAM Airlines · LA 4409 Depart at 12:41pm from Orlando (MCO) Fly for 4h 4m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Fri Nov 28th 2025 LATAM Airlines · LA 4030 Depart at 6:20pm from Bogotá (BOG) Fly for 1h 0m Arrive at 7:20pm in Medellín (MDE)
US$326

5:05pm - 7:41am
Sat Nov 29th 2025

14h 36m
Orlando (MCO) → Medellín (MDE)

2 Stops

Sat Nov 29th 2025 Volaris · Y4 781 Depart at 5:05pm from Orlando (MCO) Fly for 3h 40m Arrive at 7:45pm in Mexico City (MEX)

Layover in Mexico City for 3h 30m

Sat Nov 29th 2025 Avianca · AV 23 Depart at 11:15pm from Mexico City (MEX) Fly for 4h 25m Arrive at 4:40am in Bogotá (BOG)

Layover in Bogotá for 2h 0m

Sun Nov 30th 2025 Avianca · AV 8430 Depart at 6:40am from Bogotá (BOG) Fly for 1h 1m Arrive at 7:41am in Medellín (MDE)
US$327

4:58pm - 6:59am
Sat Nov 29th 2025

14h 1m
Orlando (MCO) → Medellín (EOH)

2 Stops

Sat Nov 29th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 1h 59m

Sat Nov 29th 2025 Copa Airlines · CM 430 Depart at 10:26pm from Panama (PTY) Fly for 1h 40m Arrive at 12:06am in Bogotá (BOG)

Layover in Bogotá for 5h 44m

Sun Nov 30th 2025 SATENA · 9R 8604 Depart at 5:50am from Bogotá (BOG) Fly for 1h 9m Arrive at 6:59am in Medellín (EOH)
US$330

5:05pm - 10:05am
Thu Nov 27th 2025

17h 0m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Volaris · Y4 781 Depart at 5:05pm from Orlando (MCO) Fly for 3h 40m Arrive at 7:45pm in Mexico City (MEX)

Layover in Mexico City for 9h 15m

Fri Nov 28th 2025 Avianca · AV 235 Depart at 5:00am from Mexico City (MEX) Fly for 4h 5m Arrive at 10:05am in Medellín (MDE)
US$334

4:58pm - 2:05am
Thu Nov 27th 2025

9h 7m
Orlando (MCO) → Medellín (MDE)

2 Stops

Thu Nov 27th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 54m

Thu Nov 27th 2025 Copa Airlines · CM 876 Depart at 9:21pm from Panama (PTY) Fly for 1h 40m Arrive at 11:01pm in Bogotá (BOG)

Layover in Bogotá for 2h 4m

Fri Nov 28th 2025 LATAM Airlines · LA 4010 Depart at 1:05am from Bogotá (BOG) Fly for 1h 0m Arrive at 2:05am in Medellín (MDE)
US$339

7:41pm - 10:05am
Thu Nov 27th 2025

14h 24m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 AeroMéxico · AM 435 Depart at 7:41pm from Orlando (MCO) Fly for 3h 54m Arrive at 10:35pm in Mexico City (MEX)

Layover in Mexico City for 6h 25m

Fri Nov 28th 2025 Avianca · AV 235 Depart at 5:00am from Mexico City (MEX) Fly for 4h 5m Arrive at 10:05am in Medellín (MDE)
US$340

7:41pm - 10:05am
Fri Nov 28th 2025

14h 24m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 AeroMéxico · AM 435 Depart at 7:41pm from Orlando (MCO) Fly for 3h 54m Arrive at 10:35pm in Mexico City (MEX)

Layover in Mexico City for 6h 25m

Sat Nov 29th 2025 Avianca · AV 235 Depart at 5:00am from Mexico City (MEX) Fly for 4h 5m Arrive at 10:05am in Medellín (MDE)
US$345

2:40pm - 8:48pm
Sat Nov 29th 2025

6h 8m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 1h 17m

Sat Nov 29th 2025 Avianca · AV 9312 Depart at 7:52pm from Bogotá (BOG) Fly for 0h 56m Arrive at 8:48pm in Medellín (MDE)
US$345

2:40pm - 8:48pm
Sun Nov 30th 2025

6h 8m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Avianca · AV 219 Depart at 2:40pm from Orlando (MCO) Fly for 3h 55m Arrive at 6:35pm in Bogotá (BOG)

Layover in Bogotá for 1h 17m

Sun Nov 30th 2025 Avianca · AV 9312 Depart at 7:52pm from Bogotá (BOG) Fly for 0h 56m Arrive at 8:48pm in Medellín (MDE)
US$345

1:55pm - 8:15pm
Sun Nov 30th 2025

6h 20m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 Avianca · AV 29 Depart at 1:55pm from Orlando (MCO) Fly for 3h 59m Arrive at 5:54pm in Bogotá (BOG)

Layover in Bogotá for 1h 25m

Sun Nov 30th 2025 Avianca · AV 9332 Depart at 7:19pm from Bogotá (BOG) Fly for 0h 56m Arrive at 8:15pm in Medellín (MDE)
US$350

4:06pm - 6:30am
Sun Nov 30th 2025

14h 24m
Orlando (MCO) → Medellín (EOH)

1 Stop

Sun Nov 30th 2025 LATAM Airlines · LA 4407 Depart at 4:06pm from Orlando (MCO) Fly for 4h 4m Arrive at 8:10pm in Bogotá (BOG)

Layover in Bogotá for 9h 10m

Mon Dec 1st 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$354

7:13am - 5:20pm
Sun Nov 30th 2025

10h 7m
Orlando (MCO) → Medellín (EOH)

2 Stops

Sun Nov 30th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 1h 26m

Sun Nov 30th 2025 Copa Airlines · CM 415 Depart at 12:08pm from Panama (PTY) Fly for 1h 40m Arrive at 1:48pm in Bogotá (BOG)

Layover in Bogotá for 2h 22m

Sun Nov 30th 2025 Clic · VE 9128 Depart at 4:10pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:20pm in Medellín (EOH)
US$354

7:41pm - 10:05am
Sat Nov 29th 2025

14h 24m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 AeroMéxico · AM 435 Depart at 7:41pm from Orlando (MCO) Fly for 3h 54m Arrive at 10:35pm in Mexico City (MEX)

Layover in Mexico City for 6h 25m

Sun Nov 30th 2025 Avianca · AV 235 Depart at 5:00am from Mexico City (MEX) Fly for 4h 5m Arrive at 10:05am in Medellín (MDE)
US$368

4:58pm - 10:51pm
Thu Nov 27th 2025

5h 53m
Orlando (MCO) → Medellín (MDE)

1 Stop

Thu Nov 27th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 59m

Thu Nov 27th 2025 Copa Airlines · CM 155 Depart at 9:26pm from Panama (PTY) Fly for 1h 25m Arrive at 10:51pm in Medellín (MDE)
US$368

12:41pm - 7:20pm
Sun Nov 30th 2025

6h 39m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sun Nov 30th 2025 LATAM Airlines · LA 4409 Depart at 12:41pm from Orlando (MCO) Fly for 4h 4m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Sun Nov 30th 2025 LATAM Airlines · LA 4030 Depart at 6:20pm from Bogotá (BOG) Fly for 1h 0m Arrive at 7:20pm in Medellín (MDE)
US$369

7:13am - 5:20pm
Fri Nov 28th 2025

10h 7m
Orlando (MCO) → Medellín (EOH)

2 Stops

Fri Nov 28th 2025 Copa Airlines · CM 435 Depart at 7:13am from Orlando (MCO) Fly for 3h 29m Arrive at 10:42am in Panama (PTY)

Layover in Panama for 1h 26m

Fri Nov 28th 2025 Copa Airlines · CM 415 Depart at 12:08pm from Panama (PTY) Fly for 1h 40m Arrive at 1:48pm in Bogotá (BOG)

Layover in Bogotá for 2h 22m

Fri Nov 28th 2025 Clic · VE 9128 Depart at 4:10pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:20pm in Medellín (EOH)
US$369

4:58pm - 10:51pm
Fri Nov 28th 2025

5h 53m
Orlando (MCO) → Medellín (MDE)

1 Stop

Fri Nov 28th 2025 Copa Airlines · CM 445 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 59m

Fri Nov 28th 2025 Copa Airlines · CM 155 Depart at 9:26pm from Panama (PTY) Fly for 1h 25m Arrive at 10:51pm in Medellín (MDE)
US$389

12:41pm - 7:20pm
Sat Nov 29th 2025

6h 39m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 LATAM Airlines · LA 4409 Depart at 12:41pm from Orlando (MCO) Fly for 4h 4m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Sat Nov 29th 2025 LATAM Airlines · LA 4030 Depart at 6:20pm from Bogotá (BOG) Fly for 1h 0m Arrive at 7:20pm in Medellín (MDE)
US$7689

4:58pm - 10:51pm
Sat Nov 29th 2025

5h 53m
Orlando (MCO) → Medellín (MDE)

1 Stop

Sat Nov 29th 2025 United Airlines · UA 7147 Depart at 4:58pm from Orlando (MCO) Fly for 3h 29m Arrive at 8:27pm in Panama (PTY)

Layover in Panama for 0h 59m

Sat Nov 29th 2025 United Airlines · UA 7096 Depart at 9:26pm from Panama (PTY) Fly for 1h 25m Arrive at 10:51pm in Medellín (MDE)

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality. It's designed for remote workers, backpackers, and people living abroad.

Read Sonaa's 7 Amazing Skyscanner Alternatives for Booking Travel

ANDY TRAVELS

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Read Josh's Ultimate Guide To Find Cheap One Way Flights

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Read Wesley's My Best Cheap Flight Hacks (Why Pay More?)

Cheap Flights from Orlando to Rio Negro (MCO to MDE)

Sarah Belizaire

John Ford

Roaming Sonaa

ANDY TRAVELS

Travel With Bender

Wesley Mergard

Latest Cheap Flight Searches

FlightList Blog

Flightlist Interviews 7 Travel Experts On Why They Book One Way Flights

Why I Built FlightList & Solved My Own Problem

About FlightList