Flights from Minneapolis to Knoxville (MSP to TYS)

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US$349

11:15am - 11:00pm
Sat Feb 22nd 2025

10h 45m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 3520 Depart at 11:15am from Minneapolis (MSP) Fly for 1h 42m Arrive at 12:57pm in Chicago (ORD)

Layover in Chicago for 7h 18m

Sat Feb 22nd 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$349

9:45am - 11:00pm
Sat Feb 22nd 2025

12h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 752 Depart at 9:45am from Minneapolis (MSP) Fly for 1h 39m Arrive at 11:24am in Chicago (ORD)

Layover in Chicago for 8h 51m

Sat Feb 22nd 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$349

8:00am - 11:00pm
Sat Feb 22nd 2025

14h 0m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 10h 37m

Sat Feb 22nd 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$349

6:00am - 11:00pm
Sat Feb 22nd 2025

16h 0m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 1705 Depart at 6:00am from Minneapolis (MSP) Fly for 1h 39m Arrive at 7:39am in Chicago (ORD)

Layover in Chicago for 12h 36m

Sat Feb 22nd 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$505

8:00am - 1:15pm
Thu Feb 20th 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Thu Feb 20th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$505

11:37am - 4:54pm
Thu Feb 20th 2025

4h 17m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 356 Depart at 11:37am from Minneapolis (MSP) Fly for 1h 37m Arrive at 1:14pm in Chicago (ORD)

Layover in Chicago for 0h 56m

Thu Feb 20th 2025 United Airlines · UA 5379 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$505

5:17pm - 11:00pm
Thu Feb 20th 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Thu Feb 20th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$505

8:05am - 2:39pm
Thu Feb 20th 2025

5h 34m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 6328 Depart at 8:05am from Minneapolis (MSP) Fly for 2h 31m Arrive at 11:36am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 19m

Thu Feb 20th 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$505

9:45am - 4:54pm
Thu Feb 20th 2025

6h 9m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 752 Depart at 9:45am from Minneapolis (MSP) Fly for 1h 39m Arrive at 11:24am in Chicago (ORD)

Layover in Chicago for 2h 46m

Thu Feb 20th 2025 United Airlines · UA 5379 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$505

6:00am - 1:15pm
Thu Feb 20th 2025

6h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 1705 Depart at 6:00am from Minneapolis (MSP) Fly for 1h 39m Arrive at 7:39am in Chicago (ORD)

Layover in Chicago for 2h 56m

Thu Feb 20th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$505

3:18pm - 11:00pm
Thu Feb 20th 2025

6h 42m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 1531 Depart at 3:18pm from Minneapolis (MSP) Fly for 1h 39m Arrive at 4:57pm in Chicago (ORD)

Layover in Chicago for 3h 18m

Thu Feb 20th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$505

1:32pm - 10:30pm
Thu Feb 20th 2025

7h 58m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 2348 Depart at 1:32pm from Minneapolis (MSP) Fly for 2h 21m Arrive at 2:53pm in Denver (DEN)

Layover in Denver for 2h 40m

Thu Feb 20th 2025 United Airlines · UA 4798 Depart at 5:33pm from Denver (DEN) Fly for 2h 57m Arrive at 10:30pm in Knoxville (TYS)
US$505

5:30am - 3:06pm
Thu Feb 20th 2025

8h 36m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 2041 Depart at 5:30am from Minneapolis (MSP) Fly for 2h 21m Arrive at 6:51am in Denver (DEN)

Layover in Denver for 3h 19m

Thu Feb 20th 2025 United Airlines · UA 5383 Depart at 10:10am from Denver (DEN) Fly for 2h 56m Arrive at 3:06pm in Knoxville (TYS)
US$541

6:00am - 2:39pm
Sat Feb 22nd 2025

7h 39m
Minneapolis (MSP) → Knoxville (TYS)

2 Stops

Sat Feb 22nd 2025 United Airlines · UA 1705 Depart at 6:00am from Minneapolis (MSP) Fly for 1h 39m Arrive at 7:39am in Chicago (ORD)

Layover in Chicago for 1h 6m

Sat Feb 22nd 2025 United Airlines · UA 545 Depart at 8:45am from Chicago (ORD) Fly for 1h 56m Arrive at 11:41am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 14m

Sat Feb 22nd 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$568

8:00am - 1:15pm
Sun Feb 23rd 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 23rd 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Sun Feb 23rd 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$568

11:37am - 4:54pm
Sun Feb 23rd 2025

4h 17m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 23rd 2025 United Airlines · UA 356 Depart at 11:37am from Minneapolis (MSP) Fly for 1h 38m Arrive at 1:15pm in Chicago (ORD)

Layover in Chicago for 0h 55m

Sun Feb 23rd 2025 United Airlines · UA 3532 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$568

5:17pm - 11:00pm
Sun Feb 23rd 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 23rd 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Sun Feb 23rd 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$568

8:05am - 2:39pm
Sat Feb 22nd 2025

5h 34m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 3430 Depart at 8:05am from Minneapolis (MSP) Fly for 2h 32m Arrive at 11:37am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 18m

Sat Feb 22nd 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$568

8:05am - 2:39pm
Sun Feb 23rd 2025

5h 34m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 23rd 2025 United Airlines · UA 6328 Depart at 8:05am from Minneapolis (MSP) Fly for 2h 31m Arrive at 11:36am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 19m

Sun Feb 23rd 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$568

12:30pm - 7:39pm
Sat Feb 22nd 2025

6h 9m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 6042 Depart at 12:30pm from Minneapolis (MSP) Fly for 2h 31m Arrive at 4:01pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 54m

Sat Feb 22nd 2025 United Airlines · UA 4914 Depart at 5:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 7:39pm in Knoxville (TYS)
US$568

6:00am - 2:02pm
Sat Feb 22nd 2025

7h 2m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 1939 Depart at 6:00am from Minneapolis (MSP) Fly for 3h 0m Arrive at 9:00am in Houston (IAH)

Layover in Houston for 1h 45m

Sat Feb 22nd 2025 United Airlines · UA 4887 Depart at 10:45am from Houston (IAH) Fly for 2h 17m Arrive at 2:02pm in Knoxville (TYS)
US$568

1:32pm - 10:30pm
Sat Feb 22nd 2025

7h 58m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 22nd 2025 United Airlines · UA 2348 Depart at 1:32pm from Minneapolis (MSP) Fly for 2h 21m Arrive at 2:53pm in Denver (DEN)

Layover in Denver for 2h 40m

Sat Feb 22nd 2025 United Airlines · UA 4798 Depart at 5:33pm from Denver (DEN) Fly for 2h 57m Arrive at 10:30pm in Knoxville (TYS)
US$588

12:30pm - 7:39pm
Thu Feb 20th 2025

6h 9m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Thu Feb 20th 2025 United Airlines · UA 3635 Depart at 12:30pm from Minneapolis (MSP) Fly for 2h 32m Arrive at 4:02pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 53m

Thu Feb 20th 2025 United Airlines · UA 4914 Depart at 5:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 7:39pm in Knoxville (TYS)
US$612

8:00am - 1:15pm
Tue Feb 18th 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Tue Feb 18th 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Tue Feb 18th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$612

8:00am - 1:15pm
Sun Feb 16th 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 16th 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Sun Feb 16th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$612

8:00am - 1:15pm
Wed Feb 19th 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Wed Feb 19th 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Wed Feb 19th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$612

11:37am - 4:54pm
Tue Feb 18th 2025

4h 17m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Tue Feb 18th 2025 United Airlines · UA 356 Depart at 11:37am from Minneapolis (MSP) Fly for 1h 37m Arrive at 1:14pm in Chicago (ORD)

Layover in Chicago for 0h 56m

Tue Feb 18th 2025 United Airlines · UA 5379 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$612

11:37am - 4:54pm
Wed Feb 19th 2025

4h 17m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Wed Feb 19th 2025 United Airlines · UA 356 Depart at 11:37am from Minneapolis (MSP) Fly for 1h 37m Arrive at 1:14pm in Chicago (ORD)

Layover in Chicago for 0h 56m

Wed Feb 19th 2025 United Airlines · UA 5379 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$612

11:37am - 4:54pm
Mon Feb 17th 2025

4h 17m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Mon Feb 17th 2025 United Airlines · UA 356 Depart at 11:37am from Minneapolis (MSP) Fly for 1h 37m Arrive at 1:14pm in Chicago (ORD)

Layover in Chicago for 0h 56m

Mon Feb 17th 2025 United Airlines · UA 5379 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$612

5:17pm - 11:00pm
Wed Feb 19th 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Wed Feb 19th 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Wed Feb 19th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$612

5:17pm - 11:00pm
Sun Feb 16th 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 16th 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Sun Feb 16th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$612

5:17pm - 11:00pm
Mon Feb 17th 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Mon Feb 17th 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Mon Feb 17th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$612

5:17pm - 11:00pm
Tue Feb 18th 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Tue Feb 18th 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Tue Feb 18th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)
US$612

8:05am - 2:39pm
Wed Feb 19th 2025

5h 34m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Wed Feb 19th 2025 United Airlines · UA 6328 Depart at 8:05am from Minneapolis (MSP) Fly for 2h 31m Arrive at 11:36am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 19m

Wed Feb 19th 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$612

8:05am - 2:39pm
Mon Feb 17th 2025

5h 34m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Mon Feb 17th 2025 United Airlines · UA 6328 Depart at 8:05am from Minneapolis (MSP) Fly for 2h 31m Arrive at 11:36am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 19m

Mon Feb 17th 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$612

8:05am - 2:39pm
Sun Feb 16th 2025

5h 34m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sun Feb 16th 2025 United Airlines · UA 6328 Depart at 8:05am from Minneapolis (MSP) Fly for 2h 31m Arrive at 11:36am in Washington, D.C. (IAD)

Layover in Washington, D.C. for 1h 19m

Sun Feb 16th 2025 United Airlines · UA 4227 Depart at 12:55pm from Washington, D.C. (IAD) Fly for 1h 44m Arrive at 2:39pm in Knoxville (TYS)
US$614

8:00am - 1:15pm
Sat Feb 15th 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 15th 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Sat Feb 15th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$614

8:00am - 1:15pm
Mon Feb 17th 2025

4h 15m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Mon Feb 17th 2025 United Airlines · UA 343 Depart at 8:00am from Minneapolis (MSP) Fly for 1h 38m Arrive at 9:38am in Chicago (ORD)

Layover in Chicago for 0h 57m

Mon Feb 17th 2025 United Airlines · UA 4505 Depart at 10:35am from Chicago (ORD) Fly for 1h 40m Arrive at 1:15pm in Knoxville (TYS)
US$614

11:15am - 4:54pm
Sat Feb 15th 2025

4h 39m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 15th 2025 United Airlines · UA 3520 Depart at 11:15am from Minneapolis (MSP) Fly for 1h 42m Arrive at 12:57pm in Chicago (ORD)

Layover in Chicago for 1h 13m

Sat Feb 15th 2025 United Airlines · UA 3592 Depart at 2:10pm from Chicago (ORD) Fly for 1h 44m Arrive at 4:54pm in Knoxville (TYS)
US$614

5:17pm - 11:00pm
Sat Feb 15th 2025

4h 43m
Minneapolis (MSP) → Knoxville (TYS)

1 Stop

Sat Feb 15th 2025 United Airlines · UA 658 Depart at 5:17pm from Minneapolis (MSP) Fly for 1h 38m Arrive at 6:55pm in Chicago (ORD)

Layover in Chicago for 1h 20m

Sat Feb 15th 2025 United Airlines · UA 1871 Depart at 8:15pm from Chicago (ORD) Fly for 1h 45m Arrive at 11:00pm in Knoxville (TYS)

Sarah Belizaire

@sarahbb1

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John Ford

@eyupitsjohn

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Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality.

Andy Travels

@andy_travels

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Travel With Bender

@travelwitbender

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Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from Minneapolis to Knoxville (MSP to TYS)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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