Flights from Manta to Guayaquil (MEC to GYE)

Discover more affordable routes and cheaper dates from Manta to Guayaquil (MEC to GYE) within a date range.

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US$140

8:50pm - 7:30am
Fri Jul 18th 2025

10h 40m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 8h 50m

Sat Jul 19th 2025 Avianca · AV 1672 Depart at 6:30am from Quito (UIO) Fly for 1h 0m Arrive at 7:30am in Guayaquil (GYE)
US$140

8:50pm - 8:45am
Fri Jul 18th 2025

11h 55m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 10h 5m

Sat Jul 19th 2025 Avianca · AV 1632 Depart at 7:45am from Quito (UIO) Fly for 1h 0m Arrive at 8:45am in Guayaquil (GYE)
US$140

9:30am - 4:35pm
Fri Jul 18th 2025

7h 5m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 5h 22m

Fri Jul 18th 2025 LATAM Airlines · LA 1353 Depart at 3:42pm from Quito (UIO) Fly for 0h 53m Arrive at 4:35pm in Guayaquil (GYE)
US$140

1:23pm - 10:23pm
Fri Jul 18th 2025

9h 0m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1695 Depart at 1:23pm from Manta (MEC) Fly for 0h 50m Arrive at 2:13pm in Quito (UIO)

Layover in Quito for 7h 17m

Fri Jul 18th 2025 LATAM Airlines · LA 1372 Depart at 9:30pm from Quito (UIO) Fly for 0h 53m Arrive at 10:23pm in Guayaquil (GYE)
US$140

8:50pm - 7:40am
Thu Jul 17th 2025

10h 50m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 9h 5m

Fri Jul 18th 2025 LATAM Airlines · LA 1411 Depart at 6:45am from Quito (UIO) Fly for 0h 55m Arrive at 7:40am in Guayaquil (GYE)
US$143

1:23pm - 7:30pm
Fri Jul 18th 2025

6h 7m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1695 Depart at 1:23pm from Manta (MEC) Fly for 0h 50m Arrive at 2:13pm in Quito (UIO)

Layover in Quito for 4h 24m

Fri Jul 18th 2025 LATAM Airlines · LA 1359 Depart at 6:37pm from Quito (UIO) Fly for 0h 53m Arrive at 7:30pm in Guayaquil (GYE)
US$143

9:30am - 7:30pm
Fri Jul 18th 2025

10h 0m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 8h 17m

Fri Jul 18th 2025 LATAM Airlines · LA 1359 Depart at 6:37pm from Quito (UIO) Fly for 0h 53m Arrive at 7:30pm in Guayaquil (GYE)
US$146

7:40am - 1:35pm
Thu Jul 17th 2025

5h 55m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 4h 12m

Thu Jul 17th 2025 LATAM Airlines · LA 1361 Depart at 12:42pm from Quito (UIO) Fly for 0h 53m Arrive at 1:35pm in Guayaquil (GYE)
US$146

7:29am - 1:35pm
Thu Jul 17th 2025

6h 6m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 LATAM Airlines · LA 1390 Depart at 7:29am from Manta (MEC) Fly for 0h 50m Arrive at 8:19am in Quito (UIO)

Layover in Quito for 4h 23m

Thu Jul 17th 2025 LATAM Airlines · LA 1361 Depart at 12:42pm from Quito (UIO) Fly for 0h 53m Arrive at 1:35pm in Guayaquil (GYE)
US$146

7:40am - 4:53pm
Thu Jul 17th 2025

9h 13m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 7h 30m

Thu Jul 17th 2025 LATAM Airlines · LA 1353 Depart at 4:00pm from Quito (UIO) Fly for 0h 53m Arrive at 4:53pm in Guayaquil (GYE)
US$146

7:29am - 4:53pm
Thu Jul 17th 2025

9h 24m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 LATAM Airlines · LA 1390 Depart at 7:29am from Manta (MEC) Fly for 0h 50m Arrive at 8:19am in Quito (UIO)

Layover in Quito for 7h 41m

Thu Jul 17th 2025 LATAM Airlines · LA 1353 Depart at 4:00pm from Quito (UIO) Fly for 0h 53m Arrive at 4:53pm in Guayaquil (GYE)
US$146

7:40am - 5:53pm
Thu Jul 17th 2025

10h 13m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 8h 30m

Thu Jul 17th 2025 LATAM Airlines · LA 1377 Depart at 5:00pm from Quito (UIO) Fly for 0h 53m Arrive at 5:53pm in Guayaquil (GYE)
US$146

7:29am - 5:53pm
Thu Jul 17th 2025

10h 24m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 LATAM Airlines · LA 1390 Depart at 7:29am from Manta (MEC) Fly for 0h 50m Arrive at 8:19am in Quito (UIO)

Layover in Quito for 8h 41m

Thu Jul 17th 2025 LATAM Airlines · LA 1377 Depart at 5:00pm from Quito (UIO) Fly for 0h 53m Arrive at 5:53pm in Guayaquil (GYE)
US$150

7:29am - 11:21am
Thu Jul 17th 2025

3h 52m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 LATAM Airlines · LA 1390 Depart at 7:29am from Manta (MEC) Fly for 0h 50m Arrive at 8:19am in Quito (UIO)

Layover in Quito for 2h 9m

Thu Jul 17th 2025 LATAM Airlines · LA 1413 Depart at 10:28am from Quito (UIO) Fly for 0h 53m Arrive at 11:21am in Guayaquil (GYE)
US$159

8:50pm - 6:55am
Thu Jul 17th 2025

10h 5m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 8h 20m

Fri Jul 18th 2025 LATAM Airlines · LA 1351 Depart at 6:00am from Quito (UIO) Fly for 0h 55m Arrive at 6:55am in Guayaquil (GYE)
US$161

1:23pm - 5:55pm
Fri Jul 18th 2025

4h 32m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1695 Depart at 1:23pm from Manta (MEC) Fly for 0h 50m Arrive at 2:13pm in Quito (UIO)

Layover in Quito for 2h 47m

Fri Jul 18th 2025 Avianca · AV 1662 Depart at 5:00pm from Quito (UIO) Fly for 0h 55m Arrive at 5:55pm in Guayaquil (GYE)
US$161

9:30am - 3:00pm
Fri Jul 18th 2025

5h 30m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 3h 45m

Fri Jul 18th 2025 Avianca · AV 1676 Depart at 2:05pm from Quito (UIO) Fly for 0h 55m Arrive at 3:00pm in Guayaquil (GYE)
US$161

9:30am - 3:55pm
Fri Jul 18th 2025

6h 25m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 4h 45m

Fri Jul 18th 2025 Avianca · AV 1660 Depart at 3:05pm from Quito (UIO) Fly for 0h 50m Arrive at 3:55pm in Guayaquil (GYE)
US$161

1:23pm - 7:55pm
Fri Jul 18th 2025

6h 32m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1695 Depart at 1:23pm from Manta (MEC) Fly for 0h 50m Arrive at 2:13pm in Quito (UIO)

Layover in Quito for 4h 47m

Fri Jul 18th 2025 Avianca · AV 1678 Depart at 7:00pm from Quito (UIO) Fly for 0h 55m Arrive at 7:55pm in Guayaquil (GYE)
US$161

7:40am - 2:25pm
Thu Jul 17th 2025

6h 45m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 5h 0m

Thu Jul 17th 2025 Avianca · AV 1660 Depart at 1:30pm from Quito (UIO) Fly for 0h 55m Arrive at 2:25pm in Guayaquil (GYE)
US$161

1:23pm - 9:33pm
Fri Jul 18th 2025

8h 10m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1695 Depart at 1:23pm from Manta (MEC) Fly for 0h 50m Arrive at 2:13pm in Quito (UIO)

Layover in Quito for 6h 25m

Fri Jul 18th 2025 Avianca · AV 1670 Depart at 8:38pm from Quito (UIO) Fly for 0h 55m Arrive at 9:33pm in Guayaquil (GYE)
US$161

7:40am - 4:00pm
Thu Jul 17th 2025

8h 20m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 6h 35m

Thu Jul 17th 2025 Avianca · AV 1674 Depart at 3:05pm from Quito (UIO) Fly for 0h 55m Arrive at 4:00pm in Guayaquil (GYE)
US$161

9:30am - 5:55pm
Fri Jul 18th 2025

8h 25m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 6h 40m

Fri Jul 18th 2025 Avianca · AV 1662 Depart at 5:00pm from Quito (UIO) Fly for 0h 55m Arrive at 5:55pm in Guayaquil (GYE)
US$161

7:40am - 5:55pm
Thu Jul 17th 2025

10h 15m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 8h 30m

Thu Jul 17th 2025 Avianca · AV 1662 Depart at 5:00pm from Quito (UIO) Fly for 0h 55m Arrive at 5:55pm in Guayaquil (GYE)
US$161

9:30am - 7:55pm
Fri Jul 18th 2025

10h 25m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 8h 40m

Fri Jul 18th 2025 Avianca · AV 1678 Depart at 7:00pm from Quito (UIO) Fly for 0h 55m Arrive at 7:55pm in Guayaquil (GYE)
US$161

7:40am - 9:33pm
Thu Jul 17th 2025

13h 53m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 12h 8m

Thu Jul 17th 2025 Avianca · AV 1670 Depart at 8:38pm from Quito (UIO) Fly for 0h 55m Arrive at 9:33pm in Guayaquil (GYE)
US$167

7:29am - 2:25pm
Thu Jul 17th 2025

6h 56m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 LATAM Airlines · LA 1390 Depart at 7:29am from Manta (MEC) Fly for 0h 50m Arrive at 8:19am in Quito (UIO)

Layover in Quito for 5h 11m

Thu Jul 17th 2025 Avianca · AV 1660 Depart at 1:30pm from Quito (UIO) Fly for 0h 55m Arrive at 2:25pm in Guayaquil (GYE)
US$172

9:30am - 12:25pm
Fri Jul 18th 2025

2h 55m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 1h 10m

Fri Jul 18th 2025 Avianca · AV 1666 Depart at 11:30am from Quito (UIO) Fly for 0h 55m Arrive at 12:25pm in Guayaquil (GYE)
US$172

7:40am - 11:25am
Thu Jul 17th 2025

3h 45m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1691 Depart at 7:40am from Manta (MEC) Fly for 0h 50m Arrive at 8:30am in Quito (UIO)

Layover in Quito for 2h 0m

Thu Jul 17th 2025 Avianca · AV 1638 Depart at 10:30am from Quito (UIO) Fly for 0h 55m Arrive at 11:25am in Guayaquil (GYE)
US$172

9:30am - 1:35pm
Fri Jul 18th 2025

4h 5m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Fri Jul 18th 2025 Avianca · AV 1693 Depart at 9:30am from Manta (MEC) Fly for 0h 50m Arrive at 10:20am in Quito (UIO)

Layover in Quito for 2h 22m

Fri Jul 18th 2025 LATAM Airlines · LA 1361 Depart at 12:42pm from Quito (UIO) Fly for 0h 53m Arrive at 1:35pm in Guayaquil (GYE)
US$172

8:50pm - 11:25am
Thu Jul 17th 2025

14h 35m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 12h 50m

Fri Jul 18th 2025 Avianca · AV 1638 Depart at 10:30am from Quito (UIO) Fly for 0h 55m Arrive at 11:25am in Guayaquil (GYE)
US$172

8:50pm - 12:25pm
Thu Jul 17th 2025

15h 35m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 13h 50m

Fri Jul 18th 2025 Avianca · AV 1666 Depart at 11:30am from Quito (UIO) Fly for 0h 55m Arrive at 12:25pm in Guayaquil (GYE)
US$179

7:29am - 11:25am
Thu Jul 17th 2025

3h 56m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 LATAM Airlines · LA 1390 Depart at 7:29am from Manta (MEC) Fly for 0h 50m Arrive at 8:19am in Quito (UIO)

Layover in Quito for 2h 11m

Thu Jul 17th 2025 Avianca · AV 1638 Depart at 10:30am from Quito (UIO) Fly for 0h 55m Arrive at 11:25am in Guayaquil (GYE)
US$185

8:50pm - 8:45am
Thu Jul 17th 2025

11h 55m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 10h 5m

Fri Jul 18th 2025 Avianca · AV 1632 Depart at 7:45am from Quito (UIO) Fly for 1h 0m Arrive at 8:45am in Guayaquil (GYE)
US$185

8:50pm - 9:00am
Thu Jul 17th 2025

12h 10m
Manta (MEC) → Guayaquil (GYE)

1 Stop

Thu Jul 17th 2025 Avianca · AV 1697 Depart at 8:50pm from Manta (MEC) Fly for 0h 50m Arrive at 9:40pm in Quito (UIO)

Layover in Quito for 10h 25m

Fri Jul 18th 2025 Avianca · AV 1630 Depart at 8:05am from Quito (UIO) Fly for 0h 55m Arrive at 9:00am in Guayaquil (GYE)

Sarah Belizaire

@sarahbb1

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John Ford

@eyupitsjohn

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Roaming Sonaa

@roamingsonaa

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Andy Travels

@andy_travels

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Travel With Bender

@travelwitbender

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Wesley Mergard

@travel.with.wes

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Flights from Manta to Guayaquil (MEC to GYE)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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