Flights from Madrid to Brussels (MAD to BRU)

Discover more affordable dates and routes for flights from Madrid to Brussels (MAD to BRU) within a date range.

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US$63.77

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 14 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$67.25

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 17 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$69.55

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 21 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$71.87

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 21 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$73

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 25 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$73

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 19 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$73

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 19 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$73

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 17 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$73.60

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 19 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$74.37

6:50am - 9:10am
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 5376 Depart at 6:50am from Madrid (MAD) Fly for 2h 20m Arrive at 9:10am in Brussels (CRL)

Stay in Brussels for 18 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$74.57

3:25pm - 5:45pm
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 5376 Depart at 3:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 5:45pm in Brussels (CRL)

Stay in Brussels for 15 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$75.35

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 24 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$77.67

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 26 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$77.77

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 14 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$78.83

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 27 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$78.83

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 27 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$78.83

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:05pm - 7:30pm
Sat Sep 27th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 17 nights

Sat Sep 27th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$78.83

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

3:10pm - 5:35pm
Thu Sep 18th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 8 nights

Thu Sep 18th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$78.83

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Oct 7th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 28 nights

Tue Oct 7th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$78.83

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 24 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$78.83

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

8:55am - 11:25am
Mon Sep 15th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 5 nights

Mon Sep 15th 2025 Ryanair · FR 2947 Depart at 8:55am from Brussels (BRU) Fly for 2h 30m Arrive at 11:25am in Madrid (MAD)
US$79.33

5:45pm - 8:05pm
Tue Sep 2nd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 2nd 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 21 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$79.39

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Sep 22nd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 12 nights

Mon Sep 22nd 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$79.39

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 27 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$79.57

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 16th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 7 nights

Tue Sep 16th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$80.15

6:50am - 9:10am
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 5376 Depart at 6:50am from Madrid (MAD) Fly for 2h 20m Arrive at 9:10am in Brussels (CRL)

Stay in Brussels for 26 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$80.36

3:25pm - 5:45pm
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 5376 Depart at 3:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 5:45pm in Brussels (CRL)

Stay in Brussels for 22 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$81.15

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 26 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$81.15

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 30 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$81.15

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 26 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$81.15

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 24 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$81.25

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 18 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$81.25

6:10am - 8:30am
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 15 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$81.71

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 26 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$82.31

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

3:10pm - 5:35pm
Thu Sep 18th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 11 nights

Thu Sep 18th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$82.31

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Oct 7th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 31 nights

Tue Oct 7th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$82.31

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:05pm - 7:30pm
Sat Sep 27th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 21 nights

Sat Sep 27th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$82.31

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

8:55am - 11:25am
Mon Sep 15th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 8 nights

Mon Sep 15th 2025 Ryanair · FR 2947 Depart at 8:55am from Brussels (BRU) Fly for 2h 30m Arrive at 11:25am in Madrid (MAD)
US$82.47

6:50am - 9:10am
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 5376 Depart at 6:50am from Madrid (MAD) Fly for 2h 20m Arrive at 9:10am in Brussels (CRL)

Stay in Brussels for 25 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$82.49

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 17th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 7 nights

Wed Sep 17th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$82.68

3:25pm - 5:45pm
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 5376 Depart at 3:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 5:45pm in Brussels (CRL)

Stay in Brussels for 22 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$82.87

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Sep 22nd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 16 nights

Mon Sep 22nd 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$83

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 16th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 10 nights

Tue Sep 16th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$84.33

7:15am - 9:35am
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 2948 Depart at 7:15am from Madrid (MAD) Fly for 2h 20m Arrive at 9:35am in Brussels (BRU)

Stay in Brussels for 20 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$85.12

5:45pm - 8:05pm
Tue Sep 2nd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 2nd 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 28 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$85.79

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:05pm - 7:30pm
Sat Sep 20th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 10 nights

Sat Sep 20th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$85.97

2:20pm - 4:40pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 17th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 5376 Depart at 2:20pm from Madrid (MAD) Fly for 2h 20m Arrive at 4:40pm in Brussels (CRL)

Stay in Brussels for 11 nights

Wed Sep 17th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$86

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

3:10pm - 5:35pm
Thu Oct 9th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 29 nights

Thu Oct 9th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$86.95

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 32 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$86.95

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 32 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$86.95

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 29 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$87

6:10am - 8:30am
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:35pm - 8:00pm
Wed Oct 1st 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 23 nights

Wed Oct 1st 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$87

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

10:35am - 1:00pm
Wed Sep 24th 2025

2h 25m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 14 nights

Wed Sep 24th 2025 Ryanair · FR 2947 Depart at 10:35am from Brussels (BRU) Fly for 2h 25m Arrive at 1:00pm in Madrid (MAD)
US$87

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 20 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$87

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 20 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$87

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 17 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$87.28

3:25pm - 5:35pm
Fri Sep 5th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Sep 23rd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 18 nights

Tue Sep 23rd 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$87.43

5:45pm - 8:05pm
Tue Sep 2nd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Sep 30th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 2nd 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 28 nights

Tue Sep 30th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$87.50

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 32 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$87.61

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 20 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$87.92

5:45pm - 8:05pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:45am - 12:10pm
Fri Sep 12th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Ryanair · FR 5376 Depart at 5:45pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:05pm in Brussels (CRL)

Stay in Brussels for 2 nights

Fri Sep 12th 2025 Ryanair · FR 5377 Depart at 9:45am from Brussels (CRL) Fly for 2h 25m Arrive at 12:10pm in Madrid (MAD)
US$88.11

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

3:10pm - 5:35pm
Thu Sep 18th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 14 nights

Thu Sep 18th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$88.11

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Oct 7th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 33 nights

Tue Oct 7th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$88.11

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:05pm - 7:30pm
Sat Sep 27th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 23 nights

Sat Sep 27th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$88.11

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

3:10pm - 5:35pm
Thu Sep 18th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 14 nights

Thu Sep 18th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$88.11

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:05pm - 7:30pm
Sat Sep 27th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 23 nights

Sat Sep 27th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$88.11

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Oct 7th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 33 nights

Tue Oct 7th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$88.11

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

5:05pm - 7:30pm
Sat Sep 27th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 20 nights

Sat Sep 27th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$88.11

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

9:05pm - 11:30pm
Tue Oct 7th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 31 nights

Tue Oct 7th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$88.11

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

3:10pm - 5:35pm
Thu Sep 18th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 11 nights

Thu Sep 18th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$88.27

6:50am - 9:10am
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 5376 Depart at 6:50am from Madrid (MAD) Fly for 2h 20m Arrive at 9:10am in Brussels (CRL)

Stay in Brussels for 31 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$88.37

6:50am - 9:10am
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 5376 Depart at 6:50am from Madrid (MAD) Fly for 2h 20m Arrive at 9:10am in Brussels (CRL)

Stay in Brussels for 19 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$88.48

3:25pm - 5:45pm
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Oct 6th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 5376 Depart at 3:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 5:45pm in Brussels (CRL)

Stay in Brussels for 28 nights

Mon Oct 6th 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$88.58

3:25pm - 5:45pm
Mon Sep 8th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:35pm - 8:00pm
Wed Sep 24th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Mon Sep 8th 2025 Ryanair · FR 5376 Depart at 3:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 5:45pm in Brussels (CRL)

Stay in Brussels for 15 nights

Wed Sep 24th 2025 Ryanair · FR 5377 Depart at 5:35pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:00pm in Madrid (MAD)
US$88.66

12:25pm - 2:45pm
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

6:30pm - 8:55pm
Mon Sep 22nd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 5376 Depart at 12:25pm from Madrid (MAD) Fly for 2h 20m Arrive at 2:45pm in Brussels (CRL)

Stay in Brussels for 18 nights

Mon Sep 22nd 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$88.66

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

9:05pm - 11:30pm
Tue Oct 7th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 33 nights

Tue Oct 7th 2025 Ryanair · FR 5377 Depart at 9:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 11:30pm in Madrid (MAD)
US$88.66

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

5:05pm - 7:30pm
Sat Sep 27th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 23 nights

Sat Sep 27th 2025 Ryanair · FR 5377 Depart at 5:05pm from Brussels (CRL) Fly for 2h 25m Arrive at 7:30pm in Madrid (MAD)
US$88.66

8:35pm - 10:55pm
Wed Sep 3rd 2025

2h 20m
Madrid (MAD) → Brussels (CRL)

Direct

3:10pm - 5:35pm
Thu Sep 18th 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Wed Sep 3rd 2025 Ryanair · FR 5376 Depart at 8:35pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:55pm in Brussels (CRL)

Stay in Brussels for 14 nights

Thu Sep 18th 2025 Ryanair · FR 5377 Depart at 3:10pm from Brussels (CRL) Fly for 2h 25m Arrive at 5:35pm in Madrid (MAD)
US$88.66

6:10am - 8:30am
Thu Sep 4th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

6:30pm - 8:55pm
Mon Sep 22nd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Thu Sep 4th 2025 Ryanair · FR 2948 Depart at 6:10am from Madrid (MAD) Fly for 2h 20m Arrive at 8:30am in Brussels (BRU)

Stay in Brussels for 18 nights

Mon Sep 22nd 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$88.66

5:40pm - 8:00pm
Sat Sep 6th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

6:30pm - 8:55pm
Mon Sep 22nd 2025

2h 25m
Brussels (CRL) → Madrid (MAD)

Direct

Sat Sep 6th 2025 Ryanair · FR 2948 Depart at 5:40pm from Madrid (MAD) Fly for 2h 20m Arrive at 8:00pm in Brussels (BRU)

Stay in Brussels for 15 nights

Mon Sep 22nd 2025 Ryanair · FR 5377 Depart at 6:30pm from Brussels (CRL) Fly for 2h 25m Arrive at 8:55pm in Madrid (MAD)
US$117.71

3:25pm - 5:35pm
Fri Sep 5th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 23rd 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 17 nights

Tue Sep 23rd 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)
US$118.47

3:25pm - 5:35pm
Fri Sep 5th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 30th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 24 nights

Tue Sep 30th 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)
US$119.35

3:25pm - 5:35pm
Fri Sep 5th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:20pm - 2:40pm
Tue Oct 7th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 31 nights

Tue Oct 7th 2025 Ryanair · FR 2947 Depart at 12:20pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:40pm in Madrid (MAD)
US$120.76

3:25pm - 5:35pm
Fri Sep 5th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 16th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 10 nights

Tue Sep 16th 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)
US$182

8:10pm - 10:30pm
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Wed Sep 24th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 18 nights

Wed Sep 24th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$182

8:10pm - 10:30pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Wed Sep 24th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 14 nights

Wed Sep 24th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$189

8:10pm - 10:30pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Tue Oct 7th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 27 nights

Tue Oct 7th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$189

8:10pm - 10:30pm
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Tue Oct 7th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 31 nights

Tue Oct 7th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$196

8:10pm - 10:30pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Thu Sep 11th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 1 night

Thu Sep 11th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$197

8:10pm - 10:30pm
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Sun Oct 5th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 29 nights

Sun Oct 5th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$197

8:10pm - 10:30pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:05am - 9:35am
Sun Oct 5th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 25 nights

Sun Oct 5th 2025 Iberia Airlines · IB 604 Depart at 7:05am from Brussels (BRU) Fly for 2h 30m Arrive at 9:35am in Madrid (MAD)
US$197

8:10pm - 10:30pm
Tue Sep 9th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:40pm - 10:10pm
Mon Sep 29th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Tue Sep 9th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 19 nights

Mon Sep 29th 2025 Iberia Airlines · IB 602 Depart at 7:40pm from Brussels (BRU) Fly for 2h 30m Arrive at 10:10pm in Madrid (MAD)
US$197

8:10pm - 10:30pm
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

7:40pm - 10:10pm
Mon Sep 29th 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 23 nights

Mon Sep 29th 2025 Iberia Airlines · IB 602 Depart at 7:40pm from Brussels (BRU) Fly for 2h 30m Arrive at 10:10pm in Madrid (MAD)
US$197

8:10pm - 10:30pm
Fri Sep 5th 2025

2h 20m
Madrid (MAD) → Brussels (BRU)

Direct

12:10pm - 2:40pm
Tue Sep 23rd 2025

2h 30m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Iberia Airlines · IB 603 Depart at 8:10pm from Madrid (MAD) Fly for 2h 20m Arrive at 10:30pm in Brussels (BRU)

Stay in Brussels for 17 nights

Tue Sep 23rd 2025 Iberia Airlines · IB 598 Depart at 12:10pm from Brussels (BRU) Fly for 2h 30m Arrive at 2:40pm in Madrid (MAD)
US$204.49

3:25pm - 5:35pm
Fri Aug 29th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 23rd 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Aug 29th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 24 nights

Tue Sep 23rd 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)
US$205.24

3:25pm - 5:35pm
Fri Aug 29th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 30th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Aug 29th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 31 nights

Tue Sep 30th 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)
US$206.12

3:25pm - 5:35pm
Fri Aug 29th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:20pm - 2:40pm
Tue Oct 7th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Aug 29th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 38 nights

Tue Oct 7th 2025 Ryanair · FR 2947 Depart at 12:20pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:40pm in Madrid (MAD)
US$207.53

3:25pm - 5:35pm
Fri Aug 29th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 16th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Aug 29th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 17 nights

Tue Sep 16th 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)
US$227.16

3:25pm - 5:35pm
Fri Sep 5th 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

9:30am - 11:50am
Wed Oct 8th 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Sep 5th 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 32 nights

Wed Oct 8th 2025 Brussels Airlines · SN 3721 Depart at 9:30am from Brussels (BRU) Fly for 2h 20m Arrive at 11:50am in Madrid (MAD)
US$259.47

3:25pm - 5:35pm
Fri Aug 22nd 2025

2h 10m
Madrid (MAD) → Brussels (BRU)

Direct

12:15pm - 2:35pm
Tue Sep 23rd 2025

2h 20m
Brussels (BRU) → Madrid (MAD)

Direct

Fri Aug 22nd 2025 Ryanair · FR 2948 Depart at 3:25pm from Madrid (MAD) Fly for 2h 10m Arrive at 5:35pm in Brussels (BRU)

Stay in Brussels for 31 nights

Tue Sep 23rd 2025 Ryanair · FR 2947 Depart at 12:15pm from Brussels (BRU) Fly for 2h 20m Arrive at 2:35pm in Madrid (MAD)

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality.

Andy Travels

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from Madrid to Brussels (MAD to BRU)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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