Cheap Flights from Lisbon to Sao Tome (LIS to TMS)

Discover more affordable routes and cheaper dates from Lisbon to Sao Tome (LIS to TMS) within a date range.

⭐ Search by country or region to discover more affordable routes, like Netherlands → Italy or Europe → South East Asia.

Results Quantity

Cabin Bags

Checked Bags

Max Budget

US$

Max Duration

Hours

Max Layover

Hours

Departure Time

Connections

Select Airlines

Loading…

€1436

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

1:10pm - 11:25am
Mon Jul 7th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 1 night

Mon Jul 7th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Tue Jul 8th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€1436

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

1:10pm - 3:25pm
Fri Jul 11th 2025

25h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 5 nights

Fri Jul 11th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Fri Jul 11th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 45m

Sat Jul 12th 2025 Lufthansa · LH 1168 Depart at 1:15pm from Frankfurt (FRA) Fly for 3h 10m Arrive at 3:25pm in Lisbon (LIS)

Book Flight
€1464

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

7:55am - 3:40pm
Wed Jul 9th 2025

6h 45m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 3 nights

Wed Jul 9th 2025 TAP Portugal · TP 1532 Depart at 7:55am from São Tomé (TMS) Fly for 6h 45m Arrive at 3:40pm in Lisbon (LIS)

Book Flight
€1477

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

7:40pm - 5:20am
Wed Jul 9th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Wed Jul 9th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Wed Jul 9th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1477

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:40pm - 5:20am
Fri Jul 11th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 5 nights

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1528

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

1:10pm - 11:25am
Mon Jul 7th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 0 nights

Mon Jul 7th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Tue Jul 8th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€1528

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

1:10pm - 3:25pm
Fri Jul 11th 2025

25h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Fri Jul 11th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Fri Jul 11th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 45m

Sat Jul 12th 2025 Lufthansa · LH 1168 Depart at 1:15pm from Frankfurt (FRA) Fly for 3h 10m Arrive at 3:25pm in Lisbon (LIS)

Book Flight
€1542

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

1:10pm - 11:25am
Fri Jul 11th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 5 nights

Fri Jul 11th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Fri Jul 11th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Sat Jul 12th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€1552

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

7:40pm - 5:20am
Fri Jul 11th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 6 nights

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1552

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

7:40pm - 5:20am
Sun Jul 6th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 1 night

Sun Jul 6th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1627

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

7:10am - 2:05pm
Sat Jul 12th 2025

5h 55m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 6 nights

Sat Jul 12th 2025 EuroAtlantic Airways · YU 508 Depart at 7:10am from São Tomé (TMS) Fly for 5h 55m Arrive at 2:05pm in Lisbon (LIS)

Book Flight
€1633

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

1:10pm - 11:25am
Fri Jul 11th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Fri Jul 11th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Fri Jul 11th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Sat Jul 12th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€1635

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:55am - 3:40pm
Wed Jul 9th 2025

6h 45m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 2 nights

Wed Jul 9th 2025 TAP Portugal · TP 1532 Depart at 7:55am from São Tomé (TMS) Fly for 6h 45m Arrive at 3:40pm in Lisbon (LIS)

Book Flight
€1644

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:40pm - 5:20am
Sun Jul 6th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 0 nights

Sun Jul 6th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1718

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:10am - 2:05pm
Sat Jul 12th 2025

5h 55m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 5 nights

Sat Jul 12th 2025 EuroAtlantic Airways · YU 508 Depart at 7:10am from São Tomé (TMS) Fly for 5h 55m Arrive at 2:05pm in Lisbon (LIS)

Book Flight
€1727

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

1:10pm - 11:25am
Mon Jul 7th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 0 nights

Mon Jul 7th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Tue Jul 8th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€1727

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

1:10pm - 3:25pm
Fri Jul 11th 2025

25h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Fri Jul 11th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Fri Jul 11th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 5h 45m

Sat Jul 12th 2025 Lufthansa · LH 1168 Depart at 1:15pm from Frankfurt (FRA) Fly for 3h 10m Arrive at 3:25pm in Lisbon (LIS)

Book Flight
€1734

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:40pm - 5:20am
Wed Jul 9th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 3 nights

Wed Jul 9th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Wed Jul 9th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1743

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

9:35pm - 5:20am
Sat Jul 12th 2025

6h 45m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 7 nights

Sat Jul 12th 2025 TAP Portugal · TP 1532 Depart at 9:35pm from São Tomé (TMS) Fly for 6h 45m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1770

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

9:35pm - 5:20am
Sat Jul 12th 2025

6h 45m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 6 nights

Sat Jul 12th 2025 TAP Portugal · TP 1532 Depart at 9:35pm from São Tomé (TMS) Fly for 6h 45m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1836

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

1:10pm - 11:25am
Fri Jul 11th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Fri Jul 11th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Fri Jul 11th 2025 TAAG Angola Airlines · DT 6561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Sat Jul 12th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€1838

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

7:55am - 3:40pm
Wed Jul 9th 2025

6h 45m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 2 nights

Wed Jul 9th 2025 TAP Portugal · TP 1532 Depart at 7:55am from São Tomé (TMS) Fly for 6h 45m Arrive at 3:40pm in Lisbon (LIS)

Book Flight
€1847

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

7:40pm - 5:20am
Fri Jul 11th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 5 nights

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1847

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

7:40pm - 5:20am
Sun Jul 6th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 0 nights

Sun Jul 6th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1877

9:00am - 12:10pm
Sun Jul 6th 2025

28h 10m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:55am - 3:40pm
Wed Jul 9th 2025

6h 45m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sun Jul 6th 2025 TAAG Angola Airlines · DT 651 Depart at 9:00am from Lisbon (LIS) Fly for 7h 30m Arrive at 4:30pm in Luanda (LAD)

Layover in Luanda for 18h 0m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 510 Depart at 10:30am from Luanda (LAD) Fly for 2h 40m Arrive at 12:10pm in São Tomé (TMS)

Stay in São Tomé for 1 night

Wed Jul 9th 2025 TAP Portugal · TP 1532 Depart at 7:55am from São Tomé (TMS) Fly for 6h 45m Arrive at 3:40pm in Lisbon (LIS)

Book Flight
€1886

9:00am - 12:10pm
Sun Jul 6th 2025

28h 10m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

7:40pm - 5:20am
Fri Jul 11th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sun Jul 6th 2025 TAAG Angola Airlines · DT 651 Depart at 9:00am from Lisbon (LIS) Fly for 7h 30m Arrive at 4:30pm in Luanda (LAD)

Layover in Luanda for 18h 0m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 510 Depart at 10:30am from Luanda (LAD) Fly for 2h 40m Arrive at 12:10pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Fri Jul 11th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€1925

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

7:10am - 2:05pm
Sat Jul 12th 2025

5h 55m
São Tomé (TMS) → Lisbon (LIS)

Direct

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 5 nights

Sat Jul 12th 2025 EuroAtlantic Airways · YU 508 Depart at 7:10am from São Tomé (TMS) Fly for 5h 55m Arrive at 2:05pm in Lisbon (LIS)

Book Flight
€1935

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

1:10pm - 7:10am
Mon Jul 7th 2025

17h 0m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 1 night

Mon Jul 7th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 7h 25m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 650 Depart at 11:50pm from Luanda (LAD) Fly for 7h 20m Arrive at 7:10am in Lisbon (LIS)

Book Flight
€1941

6:40pm - 5:35pm
Sat Jul 5th 2025

23h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

7:40pm - 5:20am
Wed Jul 9th 2025

8h 40m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sat Jul 5th 2025 Royal Air Maroc · AT 983 Depart at 6:40pm from Lisbon (LIS) Fly for 1h 25m Arrive at 8:05pm in Casablanca (CMN)

Layover in Casablanca for 5h 40m

Sun Jul 6th 2025 Royal Air Maroc · AT 515 Depart at 1:45am from Casablanca (CMN) Fly for 4h 20m Arrive at 5:05am in Accra (ACC)

Layover in Accra for 10h 40m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 3 nights

Wed Jul 9th 2025 TAP Portugal · TP 1528 Depart at 7:40pm from São Tomé (TMS) Fly for 1h 35m Arrive at 9:15pm in Accra (ACC)

Layover in Accra for 1h 0m

Wed Jul 9th 2025 TAP Portugal · TP 1528 Depart at 10:15pm from Accra (ACC) Fly for 6h 5m Arrive at 5:20am in Lisbon (LIS)

Book Flight
€2026

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

1:10pm - 7:10am
Mon Jul 7th 2025

17h 0m
São Tomé (TMS) → Lisbon (LIS)

1 Stop

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 0 nights

Mon Jul 7th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 7h 25m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 650 Depart at 11:50pm from Luanda (LAD) Fly for 7h 20m Arrive at 7:10am in Lisbon (LIS)

Book Flight
€2465

4:15pm - 12:10pm
Sun Jul 6th 2025

20h 55m
Lisbon (LIS) → São Tomé (TMS)

2 Stops

1:10pm - 11:25am
Wed Jul 9th 2025

21h 15m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sun Jul 6th 2025 Lufthansa · LH 1169 Depart at 4:15pm from Lisbon (LIS) Fly for 3h 5m Arrive at 8:20pm in Frankfurt (FRA)

Layover in Frankfurt for 1h 35m

Sun Jul 6th 2025 Lufthansa · LH 560 Depart at 9:55pm from Frankfurt (FRA) Fly for 8h 35m Arrive at 5:30am in Luanda (LAD)

Layover in Luanda for 5h 0m

Mon Jul 7th 2025 TAAG Angola Airlines · DT 510 Depart at 10:30am from Luanda (LAD) Fly for 2h 40m Arrive at 12:10pm in São Tomé (TMS)

Stay in São Tomé for 2 nights

Wed Jul 9th 2025 TAAG Angola Airlines · DT 511 Depart at 1:10pm from São Tomé (TMS) Fly for 2h 15m Arrive at 4:25pm in Luanda (LAD)

Layover in Luanda for 5h 35m

Wed Jul 9th 2025 Lufthansa · LH 561 Depart at 10:00pm from Luanda (LAD) Fly for 8h 30m Arrive at 7:30am in Frankfurt (FRA)

Layover in Frankfurt for 1h 45m

Thu Jul 10th 2025 Lufthansa · LH 1166 Depart at 9:15am from Frankfurt (FRA) Fly for 3h 10m Arrive at 11:25am in Lisbon (LIS)

Book Flight
€3162

11:40am - 5:20pm
Sat Jul 5th 2025

6h 40m
Lisbon (LIS) → São Tomé (TMS)

Direct

12:30pm - 6:50pm
Thu Jul 10th 2025

29h 20m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sat Jul 5th 2025 TAP Portugal · TP 1531 Depart at 11:40am from Lisbon (LIS) Fly for 6h 40m Arrive at 5:20pm in São Tomé (TMS)

Stay in São Tomé for 4 nights

Thu Jul 10th 2025 A.P.G. Distribution System · A1 6019 Depart at 12:30pm from São Tomé (TMS) Fly for 1h 0m Arrive at 2:30pm in Libreville (LBV)

Layover in Libreville for 7h 0m

Thu Jul 10th 2025 Air France · AF 977 Depart at 9:30pm from Libreville (LBV) Fly for 7h 55m Arrive at 6:25am in Paris (CDG)

Layover in Paris for 10h 35m

Fri Jul 11th 2025 easyJet · U2 4593 Depart at 5:00pm from Paris (CDG) Fly for 2h 50m Arrive at 6:50pm in Lisbon (LIS)

Book Flight
€3257

9:55am - 5:35pm
Sun Jul 6th 2025

8h 40m
Lisbon (LIS) → São Tomé (TMS)

1 Stop

12:30pm - 6:50pm
Thu Jul 10th 2025

29h 20m
São Tomé (TMS) → Lisbon (LIS)

2 Stops

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 9:55am from Lisbon (LIS) Fly for 5h 50m Arrive at 2:45pm in Accra (ACC)

Layover in Accra for 1h 0m

Sun Jul 6th 2025 TAP Portugal · TP 1527 Depart at 3:45pm from Accra (ACC) Fly for 1h 50m Arrive at 5:35pm in São Tomé (TMS)

Stay in São Tomé for 3 nights

Thu Jul 10th 2025 A.P.G. Distribution System · A1 6019 Depart at 12:30pm from São Tomé (TMS) Fly for 1h 0m Arrive at 2:30pm in Libreville (LBV)

Layover in Libreville for 7h 0m

Thu Jul 10th 2025 Air France · AF 977 Depart at 9:30pm from Libreville (LBV) Fly for 7h 55m Arrive at 6:25am in Paris (CDG)

Layover in Paris for 10h 35m

Fri Jul 11th 2025 easyJet · U2 4593 Depart at 5:00pm from Paris (CDG) Fly for 2h 50m Arrive at 6:50pm in Lisbon (LIS)

Book Flight

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality. It's designed for remote workers, backpackers, and people living abroad.

Read Sonaa's 7 Amazing Skyscanner Alternatives for Booking Travel

ANDY TRAVELS

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Read Josh's Ultimate Guide To Find Cheap One Way Flights

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Read Wesley's My Best Cheap Flight Hacks (Why Pay More?)

Cheap Flights from Lisbon to Sao Tome (LIS to TMS)

Sarah Belizaire

John Ford

Roaming Sonaa

ANDY TRAVELS

Travel With Bender

Wesley Mergard

Latest Cheap Flight Searches

FlightList Blog

Flightlist Interviews 7 Travel Experts On Why They Book One Way Flights

Why I Built FlightList & Solved My Own Problem

About FlightList