Flights from Jacksonville to Santiago (JAX to SCL)

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US$386

10:55am - 5:14am
Mon Dec 8th 2025

40h 19m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 2m

Mon Dec 8th 2025 Avianca · AV 583 Depart at 3:50pm from Washington, D.C. (IAD) Fly for 4h 40m Arrive at 7:30pm in San Salvador (SAL)

Layover in San Salvador for 2h 45m

Mon Dec 8th 2025 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 20h 5m

Tue Dec 9th 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$392

10:55am - 2:40pm
Mon Dec 8th 2025

25h 45m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 2m

Mon Dec 8th 2025 Avianca · AV 583 Depart at 3:50pm from Washington, D.C. (IAD) Fly for 4h 40m Arrive at 7:30pm in San Salvador (SAL)

Layover in San Salvador for 2h 45m

Mon Dec 8th 2025 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 5h 25m

Tue Dec 9th 2025 Sky Airline · H2 803 Depart at 8:55am from Lima (LIM) Fly for 3h 45m Arrive at 2:40pm in Santiago de Chile (SCL)
US$392

10:55am - 10:15pm
Mon Dec 8th 2025

33h 20m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 2m

Mon Dec 8th 2025 Avianca · AV 583 Depart at 3:50pm from Washington, D.C. (IAD) Fly for 4h 40m Arrive at 7:30pm in San Salvador (SAL)

Layover in San Salvador for 2h 45m

Mon Dec 8th 2025 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 13h 0m

Tue Dec 9th 2025 Sky Airline · H2 5601 Depart at 4:30pm from Lima (LIM) Fly for 3h 45m Arrive at 10:15pm in Santiago de Chile (SCL)
US$429

12:52pm - 5:25am
Fri Dec 5th 2025

38h 33m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Fri Dec 5th 2025 Allegiant Air · G4 1138 Depart at 12:52pm from Jacksonville (JAX) Fly for 1h 58m Arrive at 2:50pm in Pittsburgh (PIT)

Layover in Pittsburgh for 15h 50m

Sat Dec 6th 2025 Spirit Airlines · NK 1450 Depart at 6:40am from Pittsburgh (PIT) Fly for 2h 41m Arrive at 9:21am in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 1h 9m

Sat Dec 6th 2025 Spirit Airlines · NK 807 Depart at 10:30am from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 2:10pm in Bogotá (BOG)

Layover in Bogotá for 7h 18m

Sat Dec 6th 2025 JetSMART · JA 791 Depart at 9:28pm from Bogotá (BOG) Fly for 5h 57m Arrive at 5:25am in Santiago de Chile (SCL)
US$434

10:55am - 3:30pm
Mon Dec 8th 2025

26h 35m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 2m

Mon Dec 8th 2025 Avianca · AV 583 Depart at 3:50pm from Washington, D.C. (IAD) Fly for 4h 40m Arrive at 7:30pm in San Salvador (SAL)

Layover in San Salvador for 2h 45m

Mon Dec 8th 2025 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 6h 20m

Tue Dec 9th 2025 LATAM Airlines · LA 2697 Depart at 9:50am from Lima (LIM) Fly for 3h 40m Arrive at 3:30pm in Santiago de Chile (SCL)
US$440

10:55am - 2:20pm
Mon Dec 15th 2025

49h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 15th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 11h 7m

Mon Dec 15th 2025 Avianca · AV 663 Depart at 11:55pm from Washington, D.C. (IAD) Fly for 4h 50m Arrive at 3:45am in San José (SJO)

Layover in San José for 22h 30m

Wed Dec 17th 2025 Avianca · AV 693 Depart at 2:15am from San José (SJO) Fly for 2h 10m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 1h 0m

Wed Dec 17th 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$441

10:55am - 2:05pm
Mon Dec 8th 2025

25h 10m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 2m

Mon Dec 8th 2025 Avianca · AV 583 Depart at 3:50pm from Washington, D.C. (IAD) Fly for 4h 40m Arrive at 7:30pm in San Salvador (SAL)

Layover in San Salvador for 2h 45m

Mon Dec 8th 2025 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 5h 0m

Tue Dec 9th 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$441

10:55am - 5:55pm
Mon Dec 8th 2025

29h 0m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 2m

Mon Dec 8th 2025 Avianca · AV 583 Depart at 3:50pm from Washington, D.C. (IAD) Fly for 4h 40m Arrive at 7:30pm in San Salvador (SAL)

Layover in San Salvador for 2h 45m

Mon Dec 8th 2025 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 8h 50m

Tue Dec 9th 2025 LATAM Airlines · LA 651 Depart at 12:20pm from Lima (LIM) Fly for 3h 35m Arrive at 5:55pm in Santiago de Chile (SCL)
US$442

5:48pm - 2:30pm
Thu Dec 4th 2025

42h 42m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Thu Dec 4th 2025 BREEZE · MX 409 Depart at 5:48pm from Jacksonville (JAX) Fly for 1h 24m Arrive at 7:12pm in Raleigh (RDU)

Layover in Raleigh for 19h 59m

Fri Dec 5th 2025 Copa Airlines · CM 467 Depart at 3:11pm from Raleigh (RDU) Fly for 4h 35m Arrive at 7:46pm in Panama (PTY)

Layover in Panama for 1h 29m

Fri Dec 5th 2025 Copa Airlines · CM 337 Depart at 9:15pm from Panama (PTY) Fly for 3h 40m Arrive at 12:55am in Lima (LIM)

Layover in Lima for 7h 56m

Sat Dec 6th 2025 JetSMART · JA 841 Depart at 8:51am from Lima (LIM) Fly for 3h 39m Arrive at 2:30pm in Santiago de Chile (SCL)
US$446

12:52pm - 5:25am
Mon Dec 8th 2025

38h 33m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 2745 Depart at 12:52pm from Jacksonville (JAX) Fly for 1h 58m Arrive at 2:50pm in Pittsburgh (PIT)

Layover in Pittsburgh for 15h 50m

Tue Dec 9th 2025 Spirit Airlines · NK 1450 Depart at 6:40am from Pittsburgh (PIT) Fly for 2h 41m Arrive at 9:21am in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 1h 9m

Tue Dec 9th 2025 Spirit Airlines · NK 807 Depart at 10:30am from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 2:10pm in Bogotá (BOG)

Layover in Bogotá for 7h 18m

Tue Dec 9th 2025 JetSMART · JA 791 Depart at 9:28pm from Bogotá (BOG) Fly for 5h 57m Arrive at 5:25am in Santiago de Chile (SCL)
US$475

2:59pm - 2:20pm
Mon Jan 5th 2026

45h 21m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Mon Jan 5th 2026 Allegiant Air · G4 387 Depart at 2:59pm from Jacksonville (JAX) Fly for 1h 51m Arrive at 4:50pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 21h 30m

Tue Jan 6th 2026 Avianca · AV 247 Depart at 2:20pm from Washington, D.C. (IAD) Fly for 5h 30m Arrive at 7:50pm in Bogotá (BOG)

Layover in Bogotá for 10h 35m

Wed Jan 7th 2026 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$477

2:59pm - 11:40pm
Mon Jan 5th 2026

30h 41m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Jan 5th 2026 Allegiant Air · G4 387 Depart at 2:59pm from Jacksonville (JAX) Fly for 1h 51m Arrive at 4:50pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 11h 40m

Tue Jan 6th 2026 Avianca · AV 581 Depart at 4:30am from Washington, D.C. (IAD) Fly for 4h 35m Arrive at 8:05am in San Salvador (SAL)

Layover in San Salvador for 1h 25m

Tue Jan 6th 2026 Avianca · AV 383 Depart at 9:30am from San Salvador (SAL) Fly for 2h 50m Arrive at 1:20pm in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Tue Jan 6th 2026 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 10m Arrive at 11:40pm in Santiago de Chile (SCL)
US$479

6:00am - 2:40pm
Tue Dec 9th 2025

30h 40m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 9th 2025 AeroMéxico · AM 3855 Depart at 6:00am from Jacksonville (JAX) Fly for 1h 15m Arrive at 7:15am in Atlanta (ATL)

Layover in Atlanta for 1h 5m

Tue Dec 9th 2025 AeroMéxico · AM 5090 Depart at 8:20am from Atlanta (ATL) Fly for 2h 40m Arrive at 11:00am in Cancún (CUN)

Layover in Cancún for 5h 55m

Tue Dec 9th 2025 Sky Airline · H2 5554 Depart at 4:55pm from Cancún (CUN) Fly for 5h 25m Arrive at 10:20pm in Lima (LIM)

Layover in Lima for 10h 35m

Wed Dec 10th 2025 Sky Airline · H2 803 Depart at 8:55am from Lima (LIM) Fly for 3h 45m Arrive at 2:40pm in Santiago de Chile (SCL)
US$488

6:46pm - 2:40pm
Wed Dec 10th 2025

17h 54m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Wed Dec 10th 2025 LATAM Airlines · LA 6536 Depart at 6:46pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:06pm in Atlanta (ATL)

Layover in Atlanta for 2h 9m

Wed Dec 10th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 3h 55m

Thu Dec 11th 2025 Sky Airline · H2 803 Depart at 8:55am from Lima (LIM) Fly for 3h 45m Arrive at 2:40pm in Santiago de Chile (SCL)
US$489

2:59pm - 5:25am
Mon Jan 5th 2026

36h 26m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Mon Jan 5th 2026 Allegiant Air · G4 387 Depart at 2:59pm from Jacksonville (JAX) Fly for 1h 51m Arrive at 4:50pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 21h 30m

Tue Jan 6th 2026 Avianca · AV 247 Depart at 2:20pm from Washington, D.C. (IAD) Fly for 5h 30m Arrive at 7:50pm in Bogotá (BOG)

Layover in Bogotá for 1h 40m

Tue Jan 6th 2026 Avianca · AV 97 Depart at 9:30pm from Bogotá (BOG) Fly for 5h 55m Arrive at 5:25am in Santiago de Chile (SCL)
US$489

9:41am - 5:55am
Sun Jan 25th 2026

42h 14m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Jan 25th 2026 BREEZE · MX 400 Depart at 9:41am from Jacksonville (JAX) Fly for 1h 46m Arrive at 10:27am in New Orleans (MSY)

Layover in New Orleans for 22h 16m

Mon Jan 26th 2026 Spirit Airlines · NK 1280 Depart at 8:43am from New Orleans (MSY) Fly for 1h 56m Arrive at 11:39am in Cancún (CUN)

Layover in Cancún for 5h 16m

Mon Jan 26th 2026 Sky Airline · H2 5554 Depart at 4:55pm from Cancún (CUN) Fly for 5h 25m Arrive at 10:20pm in Lima (LIM)

Layover in Lima for 1h 50m

Tue Jan 27th 2026 Sky Airline · H2 805 Depart at 12:10am from Lima (LIM) Fly for 3h 45m Arrive at 5:55am in Santiago de Chile (SCL)
US$491

5:48pm - 2:05pm
Thu Dec 4th 2025

42h 17m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Thu Dec 4th 2025 BREEZE · MX 409 Depart at 5:48pm from Jacksonville (JAX) Fly for 1h 24m Arrive at 7:12pm in Raleigh (RDU)

Layover in Raleigh for 19h 59m

Fri Dec 5th 2025 Copa Airlines · CM 467 Depart at 3:11pm from Raleigh (RDU) Fly for 4h 35m Arrive at 7:46pm in Panama (PTY)

Layover in Panama for 1h 29m

Fri Dec 5th 2025 Copa Airlines · CM 337 Depart at 9:15pm from Panama (PTY) Fly for 3h 40m Arrive at 12:55am in Lima (LIM)

Layover in Lima for 7h 35m

Sat Dec 6th 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$504

3:27pm - 5:14am
Tue Dec 30th 2025

35h 47m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6389 Depart at 3:27pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 4:41pm in Atlanta (ATL)

Layover in Atlanta for 5h 34m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 18h 35m

Wed Dec 31st 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$504

9:38am - 5:55am
Sun Jan 4th 2026

42h 17m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Jan 4th 2026 BREEZE · MX 400 Depart at 9:38am from Jacksonville (JAX) Fly for 1h 44m Arrive at 10:22am in New Orleans (MSY)

Layover in New Orleans for 22h 21m

Mon Jan 5th 2026 Spirit Airlines · NK 1280 Depart at 8:43am from New Orleans (MSY) Fly for 1h 56m Arrive at 11:39am in Cancún (CUN)

Layover in Cancún for 5h 16m

Mon Jan 5th 2026 Sky Airline · H2 5554 Depart at 4:55pm from Cancún (CUN) Fly for 5h 25m Arrive at 10:20pm in Lima (LIM)

Layover in Lima for 1h 50m

Tue Jan 6th 2026 Sky Airline · H2 805 Depart at 12:10am from Lima (LIM) Fly for 3h 45m Arrive at 5:55am in Santiago de Chile (SCL)
US$504

6:46pm - 5:55pm
Wed Dec 10th 2025

21h 9m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Wed Dec 10th 2025 LATAM Airlines · LA 6536 Depart at 6:46pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:06pm in Atlanta (ATL)

Layover in Atlanta for 2h 9m

Wed Dec 10th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 7h 20m

Thu Dec 11th 2025 LATAM Airlines · LA 651 Depart at 12:20pm from Lima (LIM) Fly for 3h 35m Arrive at 5:55pm in Santiago de Chile (SCL)
US$505

6:46pm - 5:10pm
Wed Dec 10th 2025

20h 24m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Wed Dec 10th 2025 LATAM Airlines · LA 6536 Depart at 6:46pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:06pm in Atlanta (ATL)

Layover in Atlanta for 2h 9m

Wed Dec 10th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 6h 35m

Thu Dec 11th 2025 LATAM Airlines · LA 643 Depart at 11:35am from Lima (LIM) Fly for 3h 35m Arrive at 5:10pm in Santiago de Chile (SCL)
US$510

5:48pm - 5:55am
Sun Dec 7th 2025

34h 7m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 BREEZE · MX 409 Depart at 5:48pm from Jacksonville (JAX) Fly for 1h 24m Arrive at 7:12pm in Raleigh (RDU)

Layover in Raleigh for 13h 8m

Mon Dec 8th 2025 LATAM Airlines · LA 6704 Depart at 8:20am from Raleigh (RDU) Fly for 2h 22m Arrive at 10:42am in Miami (MIA)

Layover in Miami for 5h 13m

Mon Dec 8th 2025 LATAM Airlines · LA 2481 Depart at 3:55pm from Miami (MIA) Fly for 5h 45m Arrive at 9:40pm in Lima (LIM)

Layover in Lima for 2h 30m

Tue Dec 9th 2025 Sky Airline · H2 805 Depart at 12:10am from Lima (LIM) Fly for 3h 45m Arrive at 5:55am in Santiago de Chile (SCL)
US$510

6:55pm - 5:14am
Tue Dec 30th 2025

32h 19m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6536 Depart at 6:55pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:15pm in Atlanta (ATL)

Layover in Atlanta for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 18h 35m

Wed Dec 31st 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$511

9:38am - 1:08am
Sun Dec 7th 2025

37h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 BREEZE · MX 400 Depart at 9:38am from Jacksonville (JAX) Fly for 1h 44m Arrive at 10:22am in New Orleans (MSY)

Layover in New Orleans for 18h 48m

Mon Dec 8th 2025 Spirit Airlines · NK 1970 Depart at 5:10am from New Orleans (MSY) Fly for 1h 53m Arrive at 8:03am in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 2h 47m

Mon Dec 8th 2025 Spirit Airlines · NK 237 Depart at 10:50am from Fort Lauderdale (FLL) Fly for 3h 26m Arrive at 2:16pm in Medellín (MDE)

Layover in Medellín for 2h 44m

Mon Dec 8th 2025 JetSMART · JA 5838 Depart at 5:00pm from Medellín (MDE) Fly for 6h 8m Arrive at 1:08am in Santiago de Chile (SCL)
US$513

7:00am - 5:14am
Tue Dec 30th 2025

20h 14m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6674 Depart at 7:00am from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:20am in Atlanta (ATL)

Layover in Atlanta for 1h 30m

Tue Dec 30th 2025 LATAM Airlines · LA 6361 Depart at 9:50am from Atlanta (ATL) Fly for 4h 0m Arrive at 1:50pm in Cartagena (CTG)

Layover in Cartagena for 3h 25m

Tue Dec 30th 2025 LATAM Airlines · LA 2391 Depart at 5:15pm from Cartagena (CTG) Fly for 3h 40m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 40m

Tue Dec 30th 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$517

3:27pm - 8:44pm
Tue Dec 30th 2025

27h 17m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6389 Depart at 3:27pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 4:41pm in Atlanta (ATL)

Layover in Atlanta for 5h 34m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 10h 5m

Wed Dec 31st 2025 JetSMART · JA 7733 Depart at 3:05pm from Lima (LIM) Fly for 3h 39m Arrive at 8:44pm in Santiago de Chile (SCL)
US$520

6:00am - 5:55am
Tue Dec 9th 2025

21h 55m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 9th 2025 AeroMéxico · AM 3855 Depart at 6:00am from Jacksonville (JAX) Fly for 1h 15m Arrive at 7:15am in Atlanta (ATL)

Layover in Atlanta for 1h 5m

Tue Dec 9th 2025 AeroMéxico · AM 5090 Depart at 8:20am from Atlanta (ATL) Fly for 2h 40m Arrive at 11:00am in Cancún (CUN)

Layover in Cancún for 5h 55m

Tue Dec 9th 2025 Sky Airline · H2 5554 Depart at 4:55pm from Cancún (CUN) Fly for 5h 25m Arrive at 10:20pm in Lima (LIM)

Layover in Lima for 1h 50m

Wed Dec 10th 2025 Sky Airline · H2 805 Depart at 12:10am from Lima (LIM) Fly for 3h 45m Arrive at 5:55am in Santiago de Chile (SCL)
US$522

10:55am - 11:40pm
Mon Dec 15th 2025

34h 45m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 15th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 11h 7m

Mon Dec 15th 2025 Avianca · AV 663 Depart at 11:55pm from Washington, D.C. (IAD) Fly for 4h 50m Arrive at 3:45am in San José (SJO)

Layover in San José for 6h 30m

Tue Dec 16th 2025 Avianca · AV 697 Depart at 10:15am from San José (SJO) Fly for 2h 10m Arrive at 1:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 5m

Tue Dec 16th 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 10m Arrive at 11:40pm in Santiago de Chile (SCL)
US$523

6:55pm - 8:44pm
Tue Dec 30th 2025

23h 49m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6536 Depart at 6:55pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:15pm in Atlanta (ATL)

Layover in Atlanta for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 10h 5m

Wed Dec 31st 2025 JetSMART · JA 7733 Depart at 3:05pm from Lima (LIM) Fly for 3h 39m Arrive at 8:44pm in Santiago de Chile (SCL)
US$525

5:25pm - 8:50am
Thu Jan 22nd 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Thu Jan 22nd 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Thu Jan 22nd 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$525

5:25pm - 8:50am
Wed Jan 21st 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Wed Jan 21st 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Wed Jan 21st 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$525

5:25pm - 8:50am
Thu Jan 15th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Thu Jan 15th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Thu Jan 15th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$525

5:25pm - 8:50am
Wed Jan 14th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Wed Jan 14th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Wed Jan 14th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$525

4:55pm - 8:50am
Mon Dec 29th 2025

13h 55m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Mon Dec 29th 2025 United Airlines · UA 1911 Depart at 4:55pm from Jacksonville (JAX) Fly for 2h 44m Arrive at 6:39pm in Houston (IAH)

Layover in Houston for 2h 6m

Mon Dec 29th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$525

4:55pm - 8:50am
Thu Jan 1st 2026

13h 55m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Thu Jan 1st 2026 United Airlines · UA 1911 Depart at 4:55pm from Jacksonville (JAX) Fly for 2h 44m Arrive at 6:39pm in Houston (IAH)

Layover in Houston for 2h 6m

Thu Jan 1st 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$530

3:27pm - 2:40pm
Tue Dec 30th 2025

21h 13m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6389 Depart at 3:27pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 4:41pm in Atlanta (ATL)

Layover in Atlanta for 5h 34m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 3h 55m

Wed Dec 31st 2025 Sky Airline · H2 803 Depart at 8:55am from Lima (LIM) Fly for 3h 45m Arrive at 2:40pm in Santiago de Chile (SCL)
US$532

6:46pm - 3:30pm
Wed Dec 10th 2025

18h 44m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Wed Dec 10th 2025 LATAM Airlines · LA 6536 Depart at 6:46pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:06pm in Atlanta (ATL)

Layover in Atlanta for 2h 9m

Wed Dec 10th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 4h 50m

Thu Dec 11th 2025 LATAM Airlines · LA 2697 Depart at 9:50am from Lima (LIM) Fly for 3h 40m Arrive at 3:30pm in Santiago de Chile (SCL)
US$533

3:27pm - 2:05pm
Tue Dec 30th 2025

20h 38m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6389 Depart at 3:27pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 4:41pm in Atlanta (ATL)

Layover in Atlanta for 5h 34m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 3h 30m

Wed Dec 31st 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$536

6:55pm - 2:40pm
Tue Dec 30th 2025

17h 45m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6536 Depart at 6:55pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:15pm in Atlanta (ATL)

Layover in Atlanta for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 3h 55m

Wed Dec 31st 2025 Sky Airline · H2 803 Depart at 8:55am from Lima (LIM) Fly for 3h 45m Arrive at 2:40pm in Santiago de Chile (SCL)
US$537

3:27pm - 7:00am
Thu Dec 25th 2025

13h 33m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Thu Dec 25th 2025 LATAM Airlines · LA 6389 Depart at 3:27pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 4:41pm in Atlanta (ATL)

Layover in Atlanta for 3h 14m

Thu Dec 25th 2025 LATAM Airlines · LA 6357 Depart at 7:55pm from Atlanta (ATL) Fly for 9h 5m Arrive at 7:00am in Santiago de Chile (SCL)
US$539

6:55pm - 2:05pm
Tue Dec 30th 2025

17h 10m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6536 Depart at 6:55pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:15pm in Atlanta (ATL)

Layover in Atlanta for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 3h 30m

Wed Dec 31st 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$539

6:55pm - 3:30pm
Tue Dec 30th 2025

18h 35m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6536 Depart at 6:55pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:15pm in Atlanta (ATL)

Layover in Atlanta for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 4h 50m

Wed Dec 31st 2025 LATAM Airlines · LA 2697 Depart at 9:50am from Lima (LIM) Fly for 3h 40m Arrive at 3:30pm in Santiago de Chile (SCL)
US$539

6:55pm - 5:20pm
Tue Dec 30th 2025

20h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6536 Depart at 6:55pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:15pm in Atlanta (ATL)

Layover in Atlanta for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 6h 50m

Wed Dec 31st 2025 LATAM Airlines · LA 639 Depart at 11:50am from Lima (LIM) Fly for 3h 30m Arrive at 5:20pm in Santiago de Chile (SCL)
US$541

7:59pm - 5:40am
Tue Dec 30th 2025

31h 41m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6613 Depart at 7:59pm from Jacksonville (JAX) Fly for 1h 18m Arrive at 9:17pm in Atlanta (ATL)

Layover in Atlanta for 1h 42m

Tue Dec 30th 2025 LATAM Airlines · LA 8994 Depart at 10:59pm from Atlanta (ATL) Fly for 1h 55m Arrive at 12:54am in Miami (MIA)

Layover in Miami for 15h 1m

Wed Dec 31st 2025 LATAM Airlines · LA 2481 Depart at 3:55pm from Miami (MIA) Fly for 5h 45m Arrive at 9:40pm in Lima (LIM)

Layover in Lima for 2h 25m

Thu Jan 1st 2026 LATAM Airlines · LA 2377 Depart at 12:05am from Lima (LIM) Fly for 3h 35m Arrive at 5:40am in Santiago de Chile (SCL)
US$542

10:55am - 8:21pm
Mon Dec 15th 2025

31h 26m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 15th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 11h 7m

Mon Dec 15th 2025 Avianca · AV 663 Depart at 11:55pm from Washington, D.C. (IAD) Fly for 4h 50m Arrive at 3:45am in San José (SJO)

Layover in San José for 4h 25m

Tue Dec 16th 2025 Copa Airlines · CM 392 Depart at 8:10am from San José (SJO) Fly for 1h 22m Arrive at 10:32am in Panama (PTY)

Layover in Panama for 1h 16m

Tue Dec 16th 2025 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 33m Arrive at 8:21pm in Santiago de Chile (SCL)
US$543

5:10pm - 5:25am
Sun Dec 7th 2025

34h 15m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 Allegiant Air · G4 1149 Depart at 5:10pm from Jacksonville (JAX) Fly for 1h 58m Arrive at 7:08pm in Pittsburgh (PIT)

Layover in Pittsburgh for 11h 32m

Mon Dec 8th 2025 Spirit Airlines · NK 1450 Depart at 6:40am from Pittsburgh (PIT) Fly for 2h 41m Arrive at 9:21am in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 1h 9m

Mon Dec 8th 2025 Spirit Airlines · NK 807 Depart at 10:30am from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 2:10pm in Bogotá (BOG)

Layover in Bogotá for 7h 18m

Mon Dec 8th 2025 JetSMART · JA 791 Depart at 9:28pm from Bogotá (BOG) Fly for 5h 57m Arrive at 5:25am in Santiago de Chile (SCL)
US$551

6:46pm - 2:05pm
Wed Dec 10th 2025

17h 19m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Wed Dec 10th 2025 LATAM Airlines · LA 6536 Depart at 6:46pm from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:06pm in Atlanta (ATL)

Layover in Atlanta for 2h 9m

Wed Dec 10th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 3h 30m

Thu Dec 11th 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$555

5:51pm - 5:55am
Sun Jan 25th 2026

34h 4m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Jan 25th 2026 BREEZE · MX 409 Depart at 5:51pm from Jacksonville (JAX) Fly for 1h 33m Arrive at 7:24pm in Raleigh (RDU)

Layover in Raleigh for 15h 6m

Mon Jan 26th 2026 LATAM Airlines · LA 6318 Depart at 10:30am from Raleigh (RDU) Fly for 1h 34m Arrive at 12:04pm in Atlanta (ATL)

Layover in Atlanta for 2h 26m

Mon Jan 26th 2026 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 3h 15m

Tue Jan 27th 2026 Sky Airline · H2 805 Depart at 12:10am from Lima (LIM) Fly for 3h 45m Arrive at 5:55am in Santiago de Chile (SCL)
US$556

5:51pm - 4:51am
Thu Jan 22nd 2026

33h 0m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Thu Jan 22nd 2026 BREEZE · MX 409 Depart at 5:51pm from Jacksonville (JAX) Fly for 1h 33m Arrive at 7:24pm in Raleigh (RDU)

Layover in Raleigh for 15h 6m

Fri Jan 23rd 2026 LATAM Airlines · LA 6318 Depart at 10:30am from Raleigh (RDU) Fly for 1h 34m Arrive at 12:04pm in Atlanta (ATL)

Layover in Atlanta for 2h 26m

Fri Jan 23rd 2026 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 25m

Fri Jan 23rd 2026 JetSMART · JA 7731 Depart at 11:20pm from Lima (LIM) Fly for 3h 31m Arrive at 4:51am in Santiago de Chile (SCL)
US$557

10:55am - 12:15pm
Mon Dec 8th 2025

23h 20m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Mon Dec 8th 2025 Allegiant Air · G4 392 Depart at 10:55am from Jacksonville (JAX) Fly for 1h 53m Arrive at 12:48pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 3h 42m

Mon Dec 8th 2025 Air Canada · AC 8619 Depart at 4:30pm from Washington, D.C. (IAD) Fly for 1h 28m Arrive at 5:58pm in Toronto (YYZ)

Layover in Toronto for 5h 32m

Mon Dec 8th 2025 Air Canada · AC 92 Depart at 11:30pm from Toronto (YYZ) Fly for 10h 45m Arrive at 12:15pm in Santiago de Chile (SCL)
US$561

9:39am - 2:40pm
Sat Jan 17th 2026

27h 1m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sat Jan 17th 2026 BREEZE · MX 502 Depart at 9:39am from Jacksonville (JAX) Fly for 5h 18m Arrive at 11:57am in Las Vegas (LAS)

Layover in Las Vegas for 2h 18m

Sat Jan 17th 2026 Avianca · AV 527 Depart at 2:15pm from Las Vegas (LAS) Fly for 4h 50m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 10m

Sat Jan 17th 2026 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 5h 25m

Sun Jan 18th 2026 Sky Airline · H2 803 Depart at 8:55am from Lima (LIM) Fly for 3h 45m Arrive at 2:40pm in Santiago de Chile (SCL)
US$562

5:10pm - 5:25am
Thu Dec 4th 2025

34h 15m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Thu Dec 4th 2025 Allegiant Air · G4 2749 Depart at 5:10pm from Jacksonville (JAX) Fly for 1h 58m Arrive at 7:08pm in Pittsburgh (PIT)

Layover in Pittsburgh for 11h 32m

Fri Dec 5th 2025 Spirit Airlines · NK 1450 Depart at 6:40am from Pittsburgh (PIT) Fly for 2h 41m Arrive at 9:21am in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 1h 9m

Fri Dec 5th 2025 Spirit Airlines · NK 807 Depart at 10:30am from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 2:10pm in Bogotá (BOG)

Layover in Bogotá for 7h 18m

Fri Dec 5th 2025 JetSMART · JA 791 Depart at 9:28pm from Bogotá (BOG) Fly for 5h 57m Arrive at 5:25am in Santiago de Chile (SCL)
US$565

5:51pm - 4:30am
Thu Jan 22nd 2026

32h 39m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Thu Jan 22nd 2026 BREEZE · MX 409 Depart at 5:51pm from Jacksonville (JAX) Fly for 1h 33m Arrive at 7:24pm in Raleigh (RDU)

Layover in Raleigh for 15h 6m

Fri Jan 23rd 2026 LATAM Airlines · LA 6318 Depart at 10:30am from Raleigh (RDU) Fly for 1h 34m Arrive at 12:04pm in Atlanta (ATL)

Layover in Atlanta for 2h 26m

Fri Jan 23rd 2026 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 0m

Fri Jan 23rd 2026 LATAM Airlines · LA 2371 Depart at 10:55pm from Lima (LIM) Fly for 3h 35m Arrive at 4:30am in Santiago de Chile (SCL)
US$565

5:48pm - 5:14am
Thu Dec 4th 2025

33h 26m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Thu Dec 4th 2025 BREEZE · MX 409 Depart at 5:48pm from Jacksonville (JAX) Fly for 1h 24m Arrive at 7:12pm in Raleigh (RDU)

Layover in Raleigh for 15h 18m

Fri Dec 5th 2025 LATAM Airlines · LA 8843 Depart at 10:30am from Raleigh (RDU) Fly for 1h 32m Arrive at 12:02pm in Atlanta (ATL)

Layover in Atlanta for 2h 28m

Fri Dec 5th 2025 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 40m

Fri Dec 5th 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$567

5:51pm - 4:51am
Sun Jan 18th 2026

33h 0m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Jan 18th 2026 BREEZE · MX 409 Depart at 5:51pm from Jacksonville (JAX) Fly for 1h 33m Arrive at 7:24pm in Raleigh (RDU)

Layover in Raleigh for 15h 6m

Mon Jan 19th 2026 LATAM Airlines · LA 6318 Depart at 10:30am from Raleigh (RDU) Fly for 1h 34m Arrive at 12:04pm in Atlanta (ATL)

Layover in Atlanta for 2h 26m

Mon Jan 19th 2026 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 25m

Mon Jan 19th 2026 JetSMART · JA 7731 Depart at 11:20pm from Lima (LIM) Fly for 3h 31m Arrive at 4:51am in Santiago de Chile (SCL)
US$568

5:25pm - 8:50am
Sun Jan 18th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Sun Jan 18th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Sun Jan 18th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

5:25pm - 8:50am
Fri Jan 16th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Fri Jan 16th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Fri Jan 16th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

5:16pm - 8:50am
Sat Dec 6th 2025

13h 34m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Sat Dec 6th 2025 United Airlines · UA 1911 Depart at 5:16pm from Jacksonville (JAX) Fly for 2h 37m Arrive at 6:53pm in Houston (IAH)

Layover in Houston for 1h 52m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

4:55pm - 8:50am
Sun Dec 28th 2025

13h 55m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Sun Dec 28th 2025 United Airlines · UA 1911 Depart at 4:55pm from Jacksonville (JAX) Fly for 2h 44m Arrive at 6:39pm in Houston (IAH)

Layover in Houston for 2h 6m

Sun Dec 28th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

10:40am - 8:50am
Sat Dec 6th 2025

20h 10m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 2281 Depart at 10:40am from Jacksonville (JAX) Fly for 2h 20m Arrive at 1:00pm in New York (EWR)

Layover in New York for 3h 8m

Sat Dec 6th 2025 United Airlines · UA 2674 Depart at 4:08pm from New York (EWR) Fly for 4h 2m Arrive at 7:10pm in Houston (IAH)

Layover in Houston for 1h 35m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

10:40am - 8:50am
Sat Dec 6th 2025

20h 10m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 2281 Depart at 10:40am from Jacksonville (JAX) Fly for 2h 20m Arrive at 1:00pm in New York (EWR)

Layover in New York for 1h 15m

Sat Dec 6th 2025 United Airlines · UA 1590 Depart at 2:15pm from New York (EWR) Fly for 4h 2m Arrive at 5:17pm in Houston (IAH)

Layover in Houston for 3h 28m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

8:10am - 8:50am
Sat Dec 6th 2025

22h 40m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 411 Depart at 8:10am from Jacksonville (JAX) Fly for 2h 44m Arrive at 9:54am in Chicago (ORD)

Layover in Chicago for 2h 51m

Sat Dec 6th 2025 United Airlines · UA 2657 Depart at 12:45pm from Chicago (ORD) Fly for 3h 0m Arrive at 3:45pm in Houston (IAH)

Layover in Houston for 5h 0m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$568

8:10am - 8:50am
Sat Dec 6th 2025

22h 40m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 411 Depart at 8:10am from Jacksonville (JAX) Fly for 2h 44m Arrive at 9:54am in Chicago (ORD)

Layover in Chicago for 0h 41m

Sat Dec 6th 2025 United Airlines · UA 2483 Depart at 10:35am from Chicago (ORD) Fly for 2h 59m Arrive at 1:34pm in Houston (IAH)

Layover in Houston for 7h 11m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$574

8:10am - 8:50am
Sat Dec 6th 2025

22h 40m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 411 Depart at 8:10am from Jacksonville (JAX) Fly for 2h 44m Arrive at 9:54am in Chicago (ORD)

Layover in Chicago for 5h 59m

Sat Dec 6th 2025 United Airlines · UA 2095 Depart at 3:53pm from Chicago (ORD) Fly for 3h 2m Arrive at 6:55pm in Houston (IAH)

Layover in Houston for 1h 50m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$574

8:10am - 8:50am
Sat Dec 6th 2025

22h 40m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 411 Depart at 8:10am from Jacksonville (JAX) Fly for 2h 44m Arrive at 9:54am in Chicago (ORD)

Layover in Chicago for 6h 51m

Sat Dec 6th 2025 United Airlines · UA 1941 Depart at 4:45pm from Chicago (ORD) Fly for 3h 2m Arrive at 7:47pm in Houston (IAH)

Layover in Houston for 0h 58m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$574

8:10am - 8:50am
Sat Dec 6th 2025

22h 40m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Dec 6th 2025 United Airlines · UA 411 Depart at 8:10am from Jacksonville (JAX) Fly for 2h 44m Arrive at 9:54am in Chicago (ORD)

Layover in Chicago for 4h 27m

Sat Dec 6th 2025 United Airlines · UA 1373 Depart at 2:21pm from Chicago (ORD) Fly for 3h 2m Arrive at 5:23pm in Houston (IAH)

Layover in Houston for 3h 22m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$574

5:51pm - 5:55am
Sun Jan 11th 2026

34h 4m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Jan 11th 2026 BREEZE · MX 409 Depart at 5:51pm from Jacksonville (JAX) Fly for 1h 33m Arrive at 7:24pm in Raleigh (RDU)

Layover in Raleigh for 12h 56m

Mon Jan 12th 2026 LATAM Airlines · LA 6704 Depart at 8:20am from Raleigh (RDU) Fly for 2h 25m Arrive at 10:45am in Miami (MIA)

Layover in Miami for 5h 10m

Mon Jan 12th 2026 LATAM Airlines · LA 2481 Depart at 3:55pm from Miami (MIA) Fly for 5h 45m Arrive at 9:40pm in Lima (LIM)

Layover in Lima for 2h 30m

Tue Jan 13th 2026 Sky Airline · H2 805 Depart at 12:10am from Lima (LIM) Fly for 3h 45m Arrive at 5:55am in Santiago de Chile (SCL)
US$575

7:00am - 4:30am
Tue Dec 30th 2025

19h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6674 Depart at 7:00am from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:20am in Atlanta (ATL)

Layover in Atlanta for 1h 30m

Tue Dec 30th 2025 LATAM Airlines · LA 6361 Depart at 9:50am from Atlanta (ATL) Fly for 4h 0m Arrive at 1:50pm in Cartagena (CTG)

Layover in Cartagena for 3h 25m

Tue Dec 30th 2025 LATAM Airlines · LA 2391 Depart at 5:15pm from Cartagena (CTG) Fly for 3h 40m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2371 Depart at 10:55pm from Lima (LIM) Fly for 3h 35m Arrive at 4:30am in Santiago de Chile (SCL)
US$578

12:52pm - 2:20pm
Mon Dec 8th 2025

23h 28m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 8th 2025 Allegiant Air · G4 2745 Depart at 12:52pm from Jacksonville (JAX) Fly for 1h 58m Arrive at 2:50pm in Pittsburgh (PIT)

Layover in Pittsburgh for 2h 54m

Mon Dec 8th 2025 Spirit Airlines · NK 141 Depart at 5:44pm from Pittsburgh (PIT) Fly for 2h 46m Arrive at 8:30pm in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 0h 30m

Mon Dec 8th 2025 Spirit Airlines · NK 862 Depart at 9:00pm from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 12:40am in Bogotá (BOG)

Layover in Bogotá for 5h 45m

Tue Dec 9th 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$578

5:25pm - 8:50am
Wed Jan 7th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Wed Jan 7th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Wed Jan 7th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$580

9:38am - 10:21pm
Sun Dec 7th 2025

34h 43m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 BREEZE · MX 400 Depart at 9:38am from Jacksonville (JAX) Fly for 1h 44m Arrive at 10:22am in New Orleans (MSY)

Layover in New Orleans for 10h 16m

Sun Dec 7th 2025 Spirit Airlines · NK 2216 Depart at 8:38pm from New Orleans (MSY) Fly for 1h 52m Arrive at 11:30pm in Orlando (MCO)

Layover in Orlando for 7h 45m

Mon Dec 8th 2025 Spirit Airlines · NK 1476 Depart at 7:15am from Orlando (MCO) Fly for 3h 48m Arrive at 11:03am in Medellín (MDE)

Layover in Medellín for 3h 10m

Mon Dec 8th 2025 JetSMART · JA 821 Depart at 2:13pm from Medellín (MDE) Fly for 6h 8m Arrive at 10:21pm in Santiago de Chile (SCL)
US$583

3:00pm - 8:20pm
Fri Jan 2nd 2026

27h 20m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Fri Jan 2nd 2026 Allegiant Air · G4 395 Depart at 3:00pm from Jacksonville (JAX) Fly for 1h 51m Arrive at 4:51pm in Washington, D.C. (IAD)

Layover in Washington, D.C. for 8h 21m

Sat Jan 3rd 2026 Copa Airlines · CM 403 Depart at 1:12am from Washington, D.C. (IAD) Fly for 5h 1m Arrive at 6:13am in Panama (PTY)

Layover in Panama for 5h 35m

Sat Jan 3rd 2026 Copa Airlines · CM 395 Depart at 11:48am from Panama (PTY) Fly for 6h 32m Arrive at 8:20pm in Santiago de Chile (SCL)
US$585

7:00am - 8:50am
Sat Dec 6th 2025

23h 50m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Sat Dec 6th 2025 United Airlines · UA 2453 Depart at 7:00am from Jacksonville (JAX) Fly for 2h 36m Arrive at 8:36am in Houston (IAH)

Layover in Houston for 12h 9m

Sat Dec 6th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$591

6:00am - 5:14am
Tue Dec 9th 2025

21h 14m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 9th 2025 AeroMéxico · AM 3855 Depart at 6:00am from Jacksonville (JAX) Fly for 1h 15m Arrive at 7:15am in Atlanta (ATL)

Layover in Atlanta for 1h 5m

Tue Dec 9th 2025 AeroMéxico · AM 5090 Depart at 8:20am from Atlanta (ATL) Fly for 2h 40m Arrive at 11:00am in Cancún (CUN)

Layover in Cancún for 4h 40m

Tue Dec 9th 2025 LATAM Airlines · LA 2459 Depart at 3:40pm from Cancún (CUN) Fly for 5h 15m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 40m

Tue Dec 9th 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$591

5:48pm - 5:40am
Sun Dec 7th 2025

33h 52m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 BREEZE · MX 409 Depart at 5:48pm from Jacksonville (JAX) Fly for 1h 24m Arrive at 7:12pm in Raleigh (RDU)

Layover in Raleigh for 13h 8m

Mon Dec 8th 2025 LATAM Airlines · LA 6704 Depart at 8:20am from Raleigh (RDU) Fly for 2h 22m Arrive at 10:42am in Miami (MIA)

Layover in Miami for 5h 13m

Mon Dec 8th 2025 LATAM Airlines · LA 2481 Depart at 3:55pm from Miami (MIA) Fly for 5h 45m Arrive at 9:40pm in Lima (LIM)

Layover in Lima for 2h 25m

Tue Dec 9th 2025 LATAM Airlines · LA 2377 Depart at 12:05am from Lima (LIM) Fly for 3h 35m Arrive at 5:40am in Santiago de Chile (SCL)
US$593

11:29am - 2:30pm
Fri Dec 12th 2025

25h 1m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Fri Dec 12th 2025 AeroMéxico · AM 4052 Depart at 11:29am from Jacksonville (JAX) Fly for 1h 14m Arrive at 12:43pm in Atlanta (ATL)

Layover in Atlanta for 5h 42m

Fri Dec 12th 2025 AeroMéxico · AM 3072 Depart at 6:25pm from Atlanta (ATL) Fly for 2h 37m Arrive at 9:02pm in Cancún (CUN)

Layover in Cancún for 4h 13m

Sat Dec 13th 2025 LATAM Airlines · LA 2457 Depart at 1:15am from Cancún (CUN) Fly for 5h 15m Arrive at 6:30am in Lima (LIM)

Layover in Lima for 2h 21m

Sat Dec 13th 2025 JetSMART · JA 841 Depart at 8:51am from Lima (LIM) Fly for 3h 39m Arrive at 2:30pm in Santiago de Chile (SCL)
US$595

5:51pm - 4:51am
Sun Jan 25th 2026

33h 0m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Jan 25th 2026 BREEZE · MX 409 Depart at 5:51pm from Jacksonville (JAX) Fly for 1h 33m Arrive at 7:24pm in Raleigh (RDU)

Layover in Raleigh for 15h 6m

Mon Jan 26th 2026 LATAM Airlines · LA 6318 Depart at 10:30am from Raleigh (RDU) Fly for 1h 34m Arrive at 12:04pm in Atlanta (ATL)

Layover in Atlanta for 2h 26m

Mon Jan 26th 2026 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 25m

Mon Jan 26th 2026 JetSMART · JA 7731 Depart at 11:20pm from Lima (LIM) Fly for 3h 31m Arrive at 4:51am in Santiago de Chile (SCL)
US$597

12:52pm - 2:20pm
Fri Dec 5th 2025

23h 28m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Fri Dec 5th 2025 Allegiant Air · G4 1138 Depart at 12:52pm from Jacksonville (JAX) Fly for 1h 58m Arrive at 2:50pm in Pittsburgh (PIT)

Layover in Pittsburgh for 2h 54m

Fri Dec 5th 2025 Spirit Airlines · NK 141 Depart at 5:44pm from Pittsburgh (PIT) Fly for 2h 46m Arrive at 8:30pm in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 0h 30m

Fri Dec 5th 2025 Spirit Airlines · NK 862 Depart at 9:00pm from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 12:40am in Bogotá (BOG)

Layover in Bogotá for 5h 45m

Sat Dec 6th 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$597

9:43am - 3:30pm
Fri Dec 5th 2025

27h 47m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Fri Dec 5th 2025 BREEZE · MX 706 Depart at 9:43am from Jacksonville (JAX) Fly for 5h 39m Arrive at 12:22pm in Los Angeles (LAX)

Layover in Los Angeles for 8h 13m

Fri Dec 5th 2025 LATAM Airlines · LA 2477 Depart at 8:35pm from Los Angeles (LAX) Fly for 8h 35m Arrive at 8:10am in Lima (LIM)

Layover in Lima for 1h 40m

Sat Dec 6th 2025 LATAM Airlines · LA 2697 Depart at 9:50am from Lima (LIM) Fly for 3h 40m Arrive at 3:30pm in Santiago de Chile (SCL)
US$613

9:38am - 2:30pm
Sun Dec 7th 2025

26h 52m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 BREEZE · MX 400 Depart at 9:38am from Jacksonville (JAX) Fly for 1h 44m Arrive at 10:22am in New Orleans (MSY)

Layover in New Orleans for 6h 9m

Sun Dec 7th 2025 Spirit Airlines · NK 2100 Depart at 4:31pm from New Orleans (MSY) Fly for 1h 57m Arrive at 7:28pm in Fort Lauderdale (FLL)

Layover in Fort Lauderdale for 1h 32m

Sun Dec 7th 2025 Spirit Airlines · NK 862 Depart at 9:00pm from Fort Lauderdale (FLL) Fly for 3h 40m Arrive at 12:40am in Bogotá (BOG)

Layover in Bogotá for 5h 55m

Mon Dec 8th 2025 LATAM Airlines · LA 575 Depart at 6:35am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:30pm in Santiago de Chile (SCL)
US$615

9:39am - 9:15pm
Sat Jan 10th 2026

33h 36m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Sat Jan 10th 2026 BREEZE · MX 502 Depart at 9:39am from Jacksonville (JAX) Fly for 5h 18m Arrive at 11:57am in Las Vegas (LAS)

Layover in Las Vegas for 3h 34m

Sat Jan 10th 2026 Volaris · Y4 741 Depart at 3:31pm from Las Vegas (LAS) Fly for 3h 39m Arrive at 9:10pm in Mexico City (MEX)

Layover in Mexico City for 12h 55m

Sun Jan 11th 2026 AeroMéxico · AM 10 Depart at 10:05am from Mexico City (MEX) Fly for 8h 10m Arrive at 9:15pm in Santiago de Chile (SCL)
US$619

7:00am - 5:14am
Tue Dec 30th 2025

20h 14m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6674 Depart at 7:00am from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:20am in Atlanta (ATL)

Layover in Atlanta for 6h 10m

Tue Dec 30th 2025 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 40m

Tue Dec 30th 2025 JetSMART · JA 7731 Depart at 11:35pm from Lima (LIM) Fly for 3h 39m Arrive at 5:14am in Santiago de Chile (SCL)
US$619

6:00am - 4:30am
Tue Dec 9th 2025

20h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 9th 2025 AeroMéxico · AM 3855 Depart at 6:00am from Jacksonville (JAX) Fly for 1h 15m Arrive at 7:15am in Atlanta (ATL)

Layover in Atlanta for 1h 5m

Tue Dec 9th 2025 AeroMéxico · AM 5090 Depart at 8:20am from Atlanta (ATL) Fly for 2h 40m Arrive at 11:00am in Cancún (CUN)

Layover in Cancún for 4h 40m

Tue Dec 9th 2025 LATAM Airlines · LA 2459 Depart at 3:40pm from Cancún (CUN) Fly for 5h 15m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 0m

Tue Dec 9th 2025 LATAM Airlines · LA 2371 Depart at 10:55pm from Lima (LIM) Fly for 3h 35m Arrive at 4:30am in Santiago de Chile (SCL)
US$622

11:29am - 2:05pm
Fri Dec 12th 2025

24h 36m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Fri Dec 12th 2025 AeroMéxico · AM 4052 Depart at 11:29am from Jacksonville (JAX) Fly for 1h 14m Arrive at 12:43pm in Atlanta (ATL)

Layover in Atlanta for 5h 42m

Fri Dec 12th 2025 AeroMéxico · AM 3072 Depart at 6:25pm from Atlanta (ATL) Fly for 2h 37m Arrive at 9:02pm in Cancún (CUN)

Layover in Cancún for 4h 13m

Sat Dec 13th 2025 LATAM Airlines · LA 2457 Depart at 1:15am from Cancún (CUN) Fly for 5h 15m Arrive at 6:30am in Lima (LIM)

Layover in Lima for 2h 0m

Sat Dec 13th 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$624

6:00am - 3:43am
Tue Dec 9th 2025

19h 43m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 9th 2025 AeroMéxico · AM 3855 Depart at 6:00am from Jacksonville (JAX) Fly for 1h 15m Arrive at 7:15am in Atlanta (ATL)

Layover in Atlanta for 1h 5m

Tue Dec 9th 2025 AeroMéxico · AM 5090 Depart at 8:20am from Atlanta (ATL) Fly for 2h 40m Arrive at 11:00am in Cancún (CUN)

Layover in Cancún for 2h 59m

Tue Dec 9th 2025 Copa Airlines · CM 326 Depart at 1:59pm from Cancún (CUN) Fly for 2h 40m Arrive at 4:39pm in Panama (PTY)

Layover in Panama for 2h 32m

Tue Dec 9th 2025 Copa Airlines · CM 474 Depart at 7:11pm from Panama (PTY) Fly for 6h 32m Arrive at 3:43am in Santiago de Chile (SCL)
US$633

1:20pm - 2:30pm
Fri Dec 12th 2025

23h 10m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Fri Dec 12th 2025 AeroMéxico · AM 3757 Depart at 1:20pm from Jacksonville (JAX) Fly for 1h 15m Arrive at 2:35pm in Atlanta (ATL)

Layover in Atlanta for 3h 50m

Fri Dec 12th 2025 AeroMéxico · AM 3072 Depart at 6:25pm from Atlanta (ATL) Fly for 2h 37m Arrive at 9:02pm in Cancún (CUN)

Layover in Cancún for 4h 13m

Sat Dec 13th 2025 LATAM Airlines · LA 2457 Depart at 1:15am from Cancún (CUN) Fly for 5h 15m Arrive at 6:30am in Lima (LIM)

Layover in Lima for 2h 21m

Sat Dec 13th 2025 JetSMART · JA 841 Depart at 8:51am from Lima (LIM) Fly for 3h 39m Arrive at 2:30pm in Santiago de Chile (SCL)
US$639

5:00pm - 3:30pm
Thu Dec 25th 2025

20h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Thu Dec 25th 2025 LATAM Airlines · LA 6515 Depart at 5:00pm from Jacksonville (JAX) Fly for 1h 18m Arrive at 6:18pm in Atlanta (ATL)

Layover in Atlanta for 3h 57m

Thu Dec 25th 2025 LATAM Airlines · LA 2483 Depart at 10:15pm from Atlanta (ATL) Fly for 6h 45m Arrive at 5:00am in Lima (LIM)

Layover in Lima for 4h 50m

Fri Dec 26th 2025 LATAM Airlines · LA 2697 Depart at 9:50am from Lima (LIM) Fly for 3h 40m Arrive at 3:30pm in Santiago de Chile (SCL)
US$651

9:39am - 2:05pm
Sat Jan 17th 2026

26h 26m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sat Jan 17th 2026 BREEZE · MX 502 Depart at 9:39am from Jacksonville (JAX) Fly for 5h 18m Arrive at 11:57am in Las Vegas (LAS)

Layover in Las Vegas for 2h 18m

Sat Jan 17th 2026 Avianca · AV 527 Depart at 2:15pm from Las Vegas (LAS) Fly for 4h 50m Arrive at 9:05pm in San Salvador (SAL)

Layover in San Salvador for 1h 10m

Sat Jan 17th 2026 Avianca · AV 429 Depart at 10:15pm from San Salvador (SAL) Fly for 4h 15m Arrive at 3:30am in Lima (LIM)

Layover in Lima for 5h 0m

Sun Jan 18th 2026 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$653

11:50am - 2:20pm
Tue Dec 9th 2025

24h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 9th 2025 WestJet · WS 7661 Depart at 11:50am from Jacksonville (JAX) Fly for 2h 19m Arrive at 2:09pm in Detroit (DTW)

Layover in Detroit for 1h 51m

Tue Dec 9th 2025 WestJet · WS 6406 Depart at 4:00pm from Detroit (DTW) Fly for 1h 23m Arrive at 5:23pm in Toronto (YYZ)

Layover in Toronto for 5h 32m

Tue Dec 9th 2025 Avianca · AV 205 Depart at 10:55pm from Toronto (YYZ) Fly for 6h 15m Arrive at 5:10am in Bogotá (BOG)

Layover in Bogotá for 1h 15m

Wed Dec 10th 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$653

6:10pm - 11:40pm
Tue Dec 2nd 2025

27h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 2nd 2025 WestJet · WS 7659 Depart at 6:10pm from Jacksonville (JAX) Fly for 2h 25m Arrive at 8:35pm in Detroit (DTW)

Layover in Detroit for 1h 3m

Tue Dec 2nd 2025 WestJet · WS 8714 Depart at 9:38pm from Detroit (DTW) Fly for 1h 20m Arrive at 10:58pm in Toronto (YYZ)

Layover in Toronto for 9h 2m

Wed Dec 3rd 2025 Avianca · AV 255 Depart at 8:00am from Toronto (YYZ) Fly for 6h 10m Arrive at 2:10pm in Bogotá (BOG)

Layover in Bogotá for 1h 20m

Wed Dec 3rd 2025 Avianca · AV 241 Depart at 3:30pm from Bogotá (BOG) Fly for 6h 10m Arrive at 11:40pm in Santiago de Chile (SCL)
US$656

2:30pm - 2:20pm
Sun Dec 7th 2025

21h 50m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 7th 2025 WestJet · WS 8057 Depart at 2:30pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 3:44pm in Atlanta (ATL)

Layover in Atlanta for 1h 6m

Sun Dec 7th 2025 WestJet · WS 7079 Depart at 4:50pm from Atlanta (ATL) Fly for 2h 14m Arrive at 7:04pm in Toronto (YYZ)

Layover in Toronto for 3h 51m

Sun Dec 7th 2025 Avianca · AV 205 Depart at 10:55pm from Toronto (YYZ) Fly for 6h 15m Arrive at 5:10am in Bogotá (BOG)

Layover in Bogotá for 1h 15m

Mon Dec 8th 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$656

2:30pm - 2:20pm
Tue Dec 2nd 2025

21h 50m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Tue Dec 2nd 2025 WestJet · WS 8057 Depart at 2:30pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 3:44pm in Atlanta (ATL)

Layover in Atlanta for 1h 6m

Tue Dec 2nd 2025 WestJet · WS 7079 Depart at 4:50pm from Atlanta (ATL) Fly for 2h 14m Arrive at 7:04pm in Toronto (YYZ)

Layover in Toronto for 3h 51m

Tue Dec 2nd 2025 Avianca · AV 205 Depart at 10:55pm from Toronto (YYZ) Fly for 6h 15m Arrive at 5:10am in Bogotá (BOG)

Layover in Bogotá for 1h 15m

Wed Dec 3rd 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$658

5:16pm - 8:50am
Tue Dec 16th 2025

13h 34m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Tue Dec 16th 2025 United Airlines · UA 1911 Depart at 5:16pm from Jacksonville (JAX) Fly for 2h 37m Arrive at 6:53pm in Houston (IAH)

Layover in Houston for 1h 52m

Tue Dec 16th 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$662

1:20pm - 2:05pm
Fri Dec 12th 2025

22h 45m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Fri Dec 12th 2025 AeroMéxico · AM 3757 Depart at 1:20pm from Jacksonville (JAX) Fly for 1h 15m Arrive at 2:35pm in Atlanta (ATL)

Layover in Atlanta for 3h 50m

Fri Dec 12th 2025 AeroMéxico · AM 3072 Depart at 6:25pm from Atlanta (ATL) Fly for 2h 37m Arrive at 9:02pm in Cancún (CUN)

Layover in Cancún for 4h 13m

Sat Dec 13th 2025 LATAM Airlines · LA 2457 Depart at 1:15am from Cancún (CUN) Fly for 5h 15m Arrive at 6:30am in Lima (LIM)

Layover in Lima for 2h 0m

Sat Dec 13th 2025 LATAM Airlines · LA 525 Depart at 8:30am from Lima (LIM) Fly for 3h 35m Arrive at 2:05pm in Santiago de Chile (SCL)
US$681

7:00am - 4:30am
Tue Dec 30th 2025

19h 30m
Jacksonville (JAX) → Santiago de Chile (SCL)

2 Stops

Tue Dec 30th 2025 LATAM Airlines · LA 6674 Depart at 7:00am from Jacksonville (JAX) Fly for 1h 20m Arrive at 8:20am in Atlanta (ATL)

Layover in Atlanta for 6h 10m

Tue Dec 30th 2025 LATAM Airlines · LA 6355 Depart at 2:30pm from Atlanta (ATL) Fly for 6h 25m Arrive at 8:55pm in Lima (LIM)

Layover in Lima for 2h 0m

Tue Dec 30th 2025 LATAM Airlines · LA 2371 Depart at 10:55pm from Lima (LIM) Fly for 3h 35m Arrive at 4:30am in Santiago de Chile (SCL)
US$692

2:30pm - 2:20pm
Mon Dec 1st 2025

21h 50m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Mon Dec 1st 2025 WestJet · WS 8057 Depart at 2:30pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 3:44pm in Atlanta (ATL)

Layover in Atlanta for 1h 6m

Mon Dec 1st 2025 WestJet · WS 7079 Depart at 4:50pm from Atlanta (ATL) Fly for 2h 12m Arrive at 7:02pm in Toronto (YYZ)

Layover in Toronto for 3h 53m

Mon Dec 1st 2025 Avianca · AV 205 Depart at 10:55pm from Toronto (YYZ) Fly for 6h 15m Arrive at 5:10am in Bogotá (BOG)

Layover in Bogotá for 1h 15m

Tue Dec 2nd 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$698

2:30pm - 2:20pm
Sun Dec 14th 2025

21h 50m
Jacksonville (JAX) → Santiago de Chile (SCL)

3 Stops

Sun Dec 14th 2025 WestJet · WS 8057 Depart at 2:30pm from Jacksonville (JAX) Fly for 1h 14m Arrive at 3:44pm in Atlanta (ATL)

Layover in Atlanta for 1h 6m

Sun Dec 14th 2025 WestJet · WS 7079 Depart at 4:50pm from Atlanta (ATL) Fly for 2h 14m Arrive at 7:04pm in Toronto (YYZ)

Layover in Toronto for 3h 51m

Sun Dec 14th 2025 Avianca · AV 205 Depart at 10:55pm from Toronto (YYZ) Fly for 6h 15m Arrive at 5:10am in Bogotá (BOG)

Layover in Bogotá for 1h 15m

Mon Dec 15th 2025 Avianca · AV 115 Depart at 6:25am from Bogotá (BOG) Fly for 5h 55m Arrive at 2:20pm in Santiago de Chile (SCL)
US$813

5:16pm - 8:50am
Wed Dec 3rd 2025

13h 34m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Wed Dec 3rd 2025 United Airlines · UA 1911 Depart at 5:16pm from Jacksonville (JAX) Fly for 2h 37m Arrive at 6:53pm in Houston (IAH)

Layover in Houston for 1h 52m

Wed Dec 3rd 2025 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$1068

5:25pm - 8:50am
Sun Jan 11th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Sun Jan 11th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Sun Jan 11th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)
US$1104

5:25pm - 8:50am
Mon Jan 26th 2026

13h 25m
Jacksonville (JAX) → Santiago de Chile (SCL)

1 Stop

Mon Jan 26th 2026 United Airlines · UA 1911 Depart at 5:25pm from Jacksonville (JAX) Fly for 2h 40m Arrive at 7:05pm in Houston (IAH)

Layover in Houston for 1h 40m

Mon Jan 26th 2026 United Airlines · UA 847 Depart at 8:45pm from Houston (IAH) Fly for 9h 5m Arrive at 8:50am in Santiago de Chile (SCL)

Sarah Belizaire

@sarahbb1

Have flexible travel plans or looking for alternative routes given the chaos? Check out all the connection possibilities via a super helpful site created by @ismaelyws flightlist.io thanks to @andy_travels for the recommendation #travel #flights

John Ford

@eyupitsjohn

There seem to be lots of sites launching at the moment that promise to find you cheap flights but not many have the professional finish of Flightlist by @ismaelyws #travel #flights

Roaming Sonaa

@roamingsonaa

For people wanting to maximize their trips, Flightlist is my newest travel hack for uncovering the coolest routes at irresistible prices. No stress, no annoying ads — just seamless flight booking with amazing functionality.

Andy Travels

@andy_travels

@ismaelyws Just tried out Flightlist for the first time. Really nice idea, well made, and just what I need at the moment 👍

Travel With Bender

@travelwitbender

Did you spot my recent article about how to score cheap one way flights? ✈️ FlightList is my new secret tool for discovering cheap routes, within a departure date range. Plus you can also search by country/region for departures & destinations. Powerful! 💪

Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from Jacksonville to Santiago (JAX to SCL)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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