Flights from Guayaquil to Rio Negro (GYE to MDE)

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US$257

11:05am - 9:34pm
Fri Jul 25th 2025

10h 29m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 2h 0m

Fri Jul 25th 2025 Avianca · AV 8472 Depart at 2:59pm from Bogotá (BOG) Fly for 1h 34m Arrive at 4:33pm in Cartagena (CTG)

Layover in Cartagena for 3h 48m

Fri Jul 25th 2025 Wingo airlines · P5 7617 Depart at 8:21pm from Cartagena (CTG) Fly for 1h 13m Arrive at 9:34pm in Medellín (MDE)
US$266

6:30pm - 8:56am
Fri Jul 25th 2025

14h 26m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Fri Jul 25th 2025 Avianca · AV 9754 Depart at 10:00pm from Bogotá (BOG) Fly for 1h 36m Arrive at 11:36pm in Cartagena (CTG)

Layover in Cartagena for 8h 7m

Sat Jul 26th 2025 JetSMART · JA 5411 Depart at 7:43am from Cartagena (CTG) Fly for 1h 13m Arrive at 8:56am in Medellín (MDE)
US$271

9:45am - 5:49pm
Fri Jul 25th 2025

8h 4m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 1h 25m

Fri Jul 25th 2025 Avianca · AV 8490 Depart at 12:59pm from Bogotá (BOG) Fly for 1h 33m Arrive at 2:32pm in Cartagena (CTG)

Layover in Cartagena for 2h 4m

Fri Jul 25th 2025 Wingo airlines · P5 7605 Depart at 4:36pm from Cartagena (CTG) Fly for 1h 13m Arrive at 5:49pm in Medellín (MDE)
US$274

6:30pm - 5:09am
Fri Jul 25th 2025

10h 39m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Fri Jul 25th 2025 Avianca · AV 9754 Depart at 10:00pm from Bogotá (BOG) Fly for 1h 36m Arrive at 11:36pm in Cartagena (CTG)

Layover in Cartagena for 4h 20m

Sat Jul 26th 2025 LATAM Airlines · LA 4291 Depart at 3:56am from Cartagena (CTG) Fly for 1h 13m Arrive at 5:09am in Medellín (MDE)
US$299

6:30pm - 12:10pm
Fri Jul 25th 2025

17h 40m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 14h 35m

Sat Jul 26th 2025 Clic · VE 9112 Depart at 11:00am from Bogotá (BOG) Fly for 1h 10m Arrive at 12:10pm in Medellín (EOH)
US$299

3:35am - 8:40am
Fri Jul 25th 2025

5h 5m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8380 Depart at 3:35am from Guayaquil (GYE) Fly for 1h 50m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 2h 5m

Fri Jul 25th 2025 Clic · VE 9110 Depart at 7:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 8:40am in Medellín (EOH)
US$299

4:15am - 9:40am
Fri Jul 25th 2025

5h 25m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 2h 20m

Fri Jul 25th 2025 Clic · VE 9106 Depart at 8:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 9:40am in Medellín (EOH)
US$299

3:35am - 9:40am
Fri Jul 25th 2025

6h 5m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8380 Depart at 3:35am from Guayaquil (GYE) Fly for 1h 50m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 3h 5m

Fri Jul 25th 2025 Clic · VE 9106 Depart at 8:30am from Bogotá (BOG) Fly for 1h 10m Arrive at 9:40am in Medellín (EOH)
US$299

9:45am - 4:00pm
Fri Jul 25th 2025

6h 15m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 3h 16m

Fri Jul 25th 2025 Clic · VE 9130 Depart at 2:50pm from Bogotá (BOG) Fly for 1h 10m Arrive at 4:00pm in Medellín (EOH)
US$299

11:05am - 5:20pm
Fri Jul 25th 2025

6h 15m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 3h 11m

Fri Jul 25th 2025 Clic · VE 9128 Depart at 4:10pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:20pm in Medellín (EOH)
US$299

9:45am - 5:20pm
Fri Jul 25th 2025

7h 35m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 4h 36m

Fri Jul 25th 2025 Clic · VE 9128 Depart at 4:10pm from Bogotá (BOG) Fly for 1h 10m Arrive at 5:20pm in Medellín (EOH)
US$299

4:15am - 1:10pm
Fri Jul 25th 2025

8h 55m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 5h 50m

Fri Jul 25th 2025 Clic · VE 9120 Depart at 12:00pm from Bogotá (BOG) Fly for 1h 10m Arrive at 1:10pm in Medellín (EOH)
US$302

6:30pm - 5:50am
Fri Jul 25th 2025

11h 20m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 8h 20m

Sat Jul 26th 2025 JetSMART · JA 5112 Depart at 4:45am from Bogotá (BOG) Fly for 1h 5m Arrive at 5:50am in Medellín (MDE)
US$304

6:30pm - 11:39pm
Fri Jul 25th 2025

5h 9m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 12m

Fri Jul 25th 2025 Wingo airlines · P5 7290 Depart at 10:37pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:39pm in Medellín (MDE)
US$304

9:45am - 3:40pm
Fri Jul 25th 2025

5h 55m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 3h 4m

Fri Jul 25th 2025 Wingo airlines · P5 7272 Depart at 2:38pm from Bogotá (BOG) Fly for 1h 2m Arrive at 3:40pm in Medellín (MDE)
US$304

11:05am - 5:57pm
Fri Jul 25th 2025

6h 52m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 3h 56m

Fri Jul 25th 2025 Wingo airlines · P5 7274 Depart at 4:55pm from Bogotá (BOG) Fly for 1h 2m Arrive at 5:57pm in Medellín (MDE)
US$305

2:50pm - 11:00pm
Fri Jul 25th 2025

8h 10m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 Avianca · AV 76 Depart at 2:50pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Fri Jul 25th 2025 JetSMART · JA 5306 Depart at 7:20pm from Bogotá (BOG) Fly for 1h 8m Arrive at 8:28pm in Cali (CLO)

Layover in Cali for 1h 38m

Fri Jul 25th 2025 JetSMART · JA 5475 Depart at 10:06pm from Cali (CLO) Fly for 0h 54m Arrive at 11:00pm in Medellín (MDE)
US$305

9:45am - 3:55pm
Fri Jul 25th 2025

6h 10m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 3h 16m

Fri Jul 25th 2025 JetSMART · JA 5120 Depart at 2:50pm from Bogotá (BOG) Fly for 1h 5m Arrive at 3:55pm in Medellín (MDE)
US$305

11:05am - 6:02pm
Fri Jul 25th 2025

6h 57m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 3h 58m

Fri Jul 25th 2025 JetSMART · JA 5112 Depart at 4:57pm from Bogotá (BOG) Fly for 1h 5m Arrive at 6:02pm in Medellín (MDE)
US$307

4:15am - 12:20pm
Fri Jul 25th 2025

8h 5m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 5h 5m

Fri Jul 25th 2025 JetSMART · JA 5131 Depart at 11:15am from Bogotá (BOG) Fly for 1h 5m Arrive at 12:20pm in Medellín (MDE)
US$308

2:50pm - 10:33pm
Fri Jul 25th 2025

7h 43m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 76 Depart at 2:50pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 4h 43m

Fri Jul 25th 2025 JetSMART · JA 5118 Depart at 9:28pm from Bogotá (BOG) Fly for 1h 5m Arrive at 10:33pm in Medellín (MDE)
US$313

6:30pm - 6:30am
Fri Jul 25th 2025

12h 0m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 8h 55m

Sat Jul 26th 2025 Clic · VE 9104 Depart at 5:20am from Bogotá (BOG) Fly for 1h 10m Arrive at 6:30am in Medellín (EOH)
US$314

4:15am - 9:35am
Fri Jul 25th 2025

5h 20m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 2h 20m

Fri Jul 25th 2025 JetSMART · JA 5122 Depart at 8:30am from Bogotá (BOG) Fly for 1h 5m Arrive at 9:35am in Medellín (MDE)
US$314

3:35am - 9:35am
Fri Jul 25th 2025

6h 0m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8380 Depart at 3:35am from Guayaquil (GYE) Fly for 1h 50m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 3h 5m

Fri Jul 25th 2025 JetSMART · JA 5122 Depart at 8:30am from Bogotá (BOG) Fly for 1h 5m Arrive at 9:35am in Medellín (MDE)
US$324

6:30pm - 11:42pm
Fri Jul 25th 2025

5h 12m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8343 Depart at 6:30pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 8:25pm in Bogotá (BOG)

Layover in Bogotá for 2h 15m

Fri Jul 25th 2025 Avianca · AV 9342 Depart at 10:40pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:42pm in Medellín (MDE)
US$324

4:15am - 10:38am
Fri Jul 25th 2025

6h 23m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 3h 30m

Fri Jul 25th 2025 Avianca · AV 9270 Depart at 9:40am from Bogotá (BOG) Fly for 0h 58m Arrive at 10:38am in Medellín (MDE)
US$324

2:50pm - 10:08pm
Fri Jul 25th 2025

7h 18m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 76 Depart at 2:50pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 4h 21m

Fri Jul 25th 2025 Avianca · AV 9250 Depart at 9:06pm from Bogotá (BOG) Fly for 1h 2m Arrive at 10:08pm in Medellín (MDE)
US$326

9:45am - 2:50pm
Fri Jul 25th 2025

5h 5m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 2h 21m

Fri Jul 25th 2025 SATENA · 9R 8604 Depart at 1:55pm from Bogotá (BOG) Fly for 0h 55m Arrive at 2:50pm in Medellín (EOH)
US$326

11:05am - 4:39pm
Fri Jul 25th 2025

5h 34m
Guayaquil (GYE) → Medellín (EOH)

1 Stop

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 2h 31m

Fri Jul 25th 2025 SATENA · 9R 8616 Depart at 3:30pm from Bogotá (BOG) Fly for 1h 9m Arrive at 4:39pm in Medellín (EOH)
US$326

2:50pm - 9:10pm
Fri Jul 25th 2025

6h 20m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 76 Depart at 2:50pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 3h 30m

Fri Jul 25th 2025 LATAM Airlines · LA 4042 Depart at 8:15pm from Bogotá (BOG) Fly for 0h 55m Arrive at 9:10pm in Medellín (MDE)
US$327

2:50pm - 8:09pm
Fri Jul 25th 2025

5h 19m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 76 Depart at 2:50pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 2h 29m

Fri Jul 25th 2025 LATAM Airlines · LA 4024 Depart at 7:14pm from Bogotá (BOG) Fly for 0h 55m Arrive at 8:09pm in Medellín (MDE)
US$327

3:35am - 8:55am
Fri Jul 25th 2025

5h 20m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8380 Depart at 3:35am from Guayaquil (GYE) Fly for 1h 50m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 2h 35m

Fri Jul 25th 2025 LATAM Airlines · LA 4010 Depart at 8:00am from Bogotá (BOG) Fly for 0h 55m Arrive at 8:55am in Medellín (MDE)
US$327

4:15am - 9:45am
Fri Jul 25th 2025

5h 30m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 2h 40m

Fri Jul 25th 2025 LATAM Airlines · LA 4006 Depart at 8:50am from Bogotá (BOG) Fly for 0h 55m Arrive at 9:45am in Medellín (MDE)
US$327

9:45am - 3:22pm
Fri Jul 25th 2025

5h 37m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 8384 Depart at 9:45am from Guayaquil (GYE) Fly for 1h 49m Arrive at 11:34am in Bogotá (BOG)

Layover in Bogotá for 2h 53m

Fri Jul 25th 2025 LATAM Airlines · LA 4018 Depart at 2:27pm from Bogotá (BOG) Fly for 0h 55m Arrive at 3:22pm in Medellín (MDE)
US$328

11:05am - 4:12pm
Fri Jul 25th 2025

5h 7m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Fri Jul 25th 2025 Avianca · AV 9326 Depart at 3:09pm from Bogotá (BOG) Fly for 1h 3m Arrive at 4:12pm in Medellín (MDE)
US$328

11:05am - 4:45pm
Fri Jul 25th 2025

5h 40m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 90 Depart at 11:05am from Guayaquil (GYE) Fly for 1h 54m Arrive at 12:59pm in Bogotá (BOG)

Layover in Bogotá for 2h 46m

Fri Jul 25th 2025 Avianca · AV 9324 Depart at 3:45pm from Bogotá (BOG) Fly for 1h 0m Arrive at 4:45pm in Medellín (MDE)
US$332

2:50pm - 8:05pm
Fri Jul 25th 2025

5h 15m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 76 Depart at 2:50pm from Guayaquil (GYE) Fly for 1h 55m Arrive at 4:45pm in Bogotá (BOG)

Layover in Bogotá for 2h 24m

Fri Jul 25th 2025 Avianca · AV 9308 Depart at 7:09pm from Bogotá (BOG) Fly for 0h 56m Arrive at 8:05pm in Medellín (MDE)
US$353

4:15am - 9:20am
Fri Jul 25th 2025

5h 5m
Guayaquil (GYE) → Medellín (MDE)

1 Stop

Fri Jul 25th 2025 Avianca · AV 96 Depart at 4:15am from Guayaquil (GYE) Fly for 1h 55m Arrive at 6:10am in Bogotá (BOG)

Layover in Bogotá for 2h 9m

Fri Jul 25th 2025 Avianca · AV 8432 Depart at 8:19am from Bogotá (BOG) Fly for 1h 1m Arrive at 9:20am in Medellín (MDE)
US$429

3:20pm - 11:02pm
Fri Jul 25th 2025

7h 42m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 Avianca · AV 1633 Depart at 3:20pm from Guayaquil (GYE) Fly for 0h 55m Arrive at 4:15pm in Quito (UIO)

Layover in Quito for 2h 0m

Fri Jul 25th 2025 Avianca · AV 8341 Depart at 6:15pm from Quito (UIO) Fly for 1h 35m Arrive at 7:50pm in Bogotá (BOG)

Layover in Bogotá for 2h 10m

Fri Jul 25th 2025 Avianca · AV 9242 Depart at 10:00pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:02pm in Medellín (MDE)
US$1943

12:17pm - 4:42am
Fri Jul 25th 2025

16h 25m
Guayaquil (GYE) → Medellín (MDE)

2 Stops

Fri Jul 25th 2025 United Airlines · UA 7054 Depart at 12:17pm from Guayaquil (GYE) Fly for 2h 10m Arrive at 2:27pm in Panama (PTY)

Layover in Panama for 1h 3m

Fri Jul 25th 2025 United Airlines · UA 1033 Depart at 3:30pm from Panama (PTY) Fly for 4h 35m Arrive at 8:05pm in Houston (IAH)

Layover in Houston for 3h 47m

Fri Jul 25th 2025 United Airlines · UA 2741 Depart at 11:52pm from Houston (IAH) Fly for 4h 50m Arrive at 4:42am in Medellín (MDE)

Sarah Belizaire

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@eyupitsjohn

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Roaming Sonaa

@roamingsonaa

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Andy Travels

@andy_travels

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Travel With Bender

@travelwitbender

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Flights from Guayaquil to Rio Negro (GYE to MDE)

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John Ford

Roaming Sonaa

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