Flights from Guatemala City to Panama (GUA to PA)

Discover more affordable routes and cheaper dates from Guatemala City to Panama (GUA to PA) within a date range.

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US$101

4:40pm - 12:20am
Wed Mar 26th 2025

6h 40m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Wed Mar 26th 2025 Avianca · AV 40 Depart at 10:30pm from Bogotá (BOG) Fly for 1h 50m Arrive at 12:20am in Panama (PTY)
US$101

7:20am - 4:30pm
Tue Mar 25th 2025

8h 10m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 165 Depart at 7:20am from Guatemala City (GUA) Fly for 3h 20m Arrive at 11:40am in Bogotá (BOG)

Layover in Bogotá for 2h 55m

Tue Mar 25th 2025 Avianca · AV 60 Depart at 2:35pm from Bogotá (BOG) Fly for 1h 55m Arrive at 4:30pm in Panama (PTY)
US$103

4:23pm - 7:50pm
Tue Mar 25th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)
US$103

1:12pm - 4:39pm
Tue Mar 25th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)
US$103

5:20am - 10:25am
Tue Mar 25th 2025

4h 5m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 1h 20m

Tue Mar 25th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$103

5:20am - 10:25am
Wed Mar 26th 2025

4h 5m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 1h 20m

Wed Mar 26th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$107

7:50am - 12:35pm
Mon Mar 24th 2025

3h 45m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 0h 55m

Mon Mar 24th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)
US$107

6:00am - 12:35pm
Tue Mar 25th 2025

5h 35m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 655 Depart at 6:00am from Guatemala City (GUA) Fly for 1h 35m Arrive at 7:35am in San José (SJO)

Layover in San José for 2h 40m

Tue Mar 25th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)
US$107

6:00am - 12:35pm
Wed Mar 26th 2025

5h 35m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 655 Depart at 6:00am from Guatemala City (GUA) Fly for 1h 35m Arrive at 7:35am in San José (SJO)

Layover in San José for 2h 40m

Wed Mar 26th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)
US$107

9:25pm - 12:35pm
Tue Mar 25th 2025

14h 10m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 641 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 11h 20m

Wed Mar 26th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)
US$107

9:25pm - 12:35pm
Wed Mar 26th 2025

14h 10m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 11h 20m

Thu Mar 27th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)
US$107

9:25pm - 12:35pm
Mon Mar 24th 2025

14h 10m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 11h 20m

Tue Mar 25th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)
US$108

10:32am - 8:30pm
Mon Mar 24th 2025

8h 58m
Guatemala City (GUA) → Panama (PTY)

2 Stops

Mon Mar 24th 2025 Copa Airlines · CM 380 Depart at 10:32am from Guatemala City (GUA) Fly for 1h 23m Arrive at 11:55am in Managua (MGA)

Layover in Managua for 3h 54m

Mon Mar 24th 2025 Copa Airlines · CM 839 Depart at 3:49pm from Managua (MGA) Fly for 0h 59m Arrive at 4:48pm in San José (SJO)

Layover in San José for 1h 18m

Mon Mar 24th 2025 Copa Airlines · CM 839 Depart at 6:06pm from San José (SJO) Fly for 1h 24m Arrive at 8:30pm in Panama (PTY)
US$112

5:39am - 10:32am
Tue Mar 25th 2025

3h 53m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Copa Airlines · CM 392 Depart at 5:39am from Guatemala City (GUA) Fly for 1h 42m Arrive at 7:21am in San José (SJO)

Layover in San José for 0h 47m

Tue Mar 25th 2025 Copa Airlines · CM 392 Depart at 8:08am from San José (SJO) Fly for 1h 24m Arrive at 10:32am in Panama (PTY)
US$112

5:39am - 10:32am
Wed Mar 26th 2025

3h 53m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Copa Airlines · CM 392 Depart at 5:39am from Guatemala City (GUA) Fly for 1h 42m Arrive at 7:21am in San José (SJO)

Layover in San José for 0h 47m

Wed Mar 26th 2025 Copa Airlines · CM 392 Depart at 8:08am from San José (SJO) Fly for 1h 24m Arrive at 10:32am in Panama (PTY)
US$114

8:10pm - 10:25am
Mon Mar 24th 2025

13h 15m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 10h 30m

Tue Mar 25th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$114

8:10pm - 10:25am
Tue Mar 25th 2025

13h 15m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 10h 30m

Wed Mar 26th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$114

8:10pm - 10:25am
Wed Mar 26th 2025

13h 15m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 10h 30m

Thu Mar 27th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$122

4:47am - 8:13am
Wed Mar 26th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Wed Mar 26th 2025 Copa Airlines · CM 407 Depart at 4:47am from Guatemala City (GUA) Fly for 2h 26m Arrive at 8:13am in Panama (PTY)
US$122

10:23am - 1:49pm
Wed Mar 26th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Wed Mar 26th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)
US$122

1:12pm - 4:39pm
Mon Mar 24th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)
US$122

4:23pm - 7:50pm
Mon Mar 24th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)
US$122

4:23pm - 7:50pm
Wed Mar 26th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Wed Mar 26th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)
US$122

7:06am - 10:36am
Wed Mar 26th 2025

2h 30m
Guatemala City (GUA) → Panama (PTY)

Direct

Wed Mar 26th 2025 Copa Airlines · CM 389 Depart at 7:06am from Guatemala City (GUA) Fly for 2h 30m Arrive at 10:36am in Panama (PTY)
US$224

9:25pm - 6:33am
Mon Mar 24th 2025

8h 8m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 5h 14m

Tue Mar 25th 2025 Copa Airlines · CM 461 Depart at 4:09am from San José (SJO) Fly for 1h 24m Arrive at 6:33am in Panama (PTY)
US$245

9:35am - 8:00am
Tue Mar 25th 2025

21h 25m
Guatemala City (GUA) → Panama (BLB)

1 Stop

Tue Mar 25th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 16h 21m

Wed Mar 26th 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)
US$251

9:25pm - 6:33am
Tue Mar 25th 2025

8h 8m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 641 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 5h 14m

Wed Mar 26th 2025 Copa Airlines · CM 461 Depart at 4:09am from San José (SJO) Fly for 1h 24m Arrive at 6:33am in Panama (PTY)
US$252

8:10pm - 8:10am
Wed Mar 26th 2025

11h 0m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 8h 1m

Thu Mar 27th 2025 Copa Airlines · CM 879 Depart at 5:01am from San Salvador (SAL) Fly for 2h 9m Arrive at 8:10am in Panama (PTY)
US$268

8:10pm - 3:16pm
Wed Mar 26th 2025

18h 6m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Wed Mar 26th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 1h 10m

Wed Mar 26th 2025 Avianca · AV 369 Depart at 10:10pm from San Salvador (SAL) Fly for 2h 45m Arrive at 1:55am in Medellín (MDE)

Layover in Medellín for 12h 1m

Thu Mar 27th 2025 Wingo airlines · P5 7046 Depart at 1:56pm from Medellín (MDE) Fly for 1h 20m Arrive at 3:16pm in Panama (BLB)
US$272

7:20am - 6:09pm
Tue Mar 25th 2025

9h 49m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Tue Mar 25th 2025 Avianca · AV 165 Depart at 7:20am from Guatemala City (GUA) Fly for 3h 20m Arrive at 11:40am in Bogotá (BOG)

Layover in Bogotá for 1h 45m

Tue Mar 25th 2025 Avianca · AV 9340 Depart at 1:25pm from Bogotá (BOG) Fly for 0h 55m Arrive at 2:20pm in Medellín (MDE)

Layover in Medellín for 2h 29m

Tue Mar 25th 2025 Wingo airlines · P5 7048 Depart at 4:49pm from Medellín (MDE) Fly for 1h 20m Arrive at 6:09pm in Panama (BLB)
US$275

9:25pm - 10:32am
Wed Mar 26th 2025

12h 7m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 9h 13m

Thu Mar 27th 2025 Copa Airlines · CM 392 Depart at 8:08am from San José (SJO) Fly for 1h 24m Arrive at 10:32am in Panama (PTY)
US$278

9:35am - 9:00pm
Mon Mar 24th 2025

10h 25m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 5h 21m

Mon Mar 24th 2025 Avianca · AV 56 Depart at 7:15pm from Bogotá (BOG) Fly for 1h 45m Arrive at 9:00pm in Panama (PTY)
US$283

9:35am - 8:56am
Wed Mar 26th 2025

22h 21m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Wed Mar 26th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 4h 14m

Wed Mar 26th 2025 Copa Airlines · CM 414 Depart at 6:08pm from Bogotá (BOG) Fly for 1h 46m Arrive at 7:54pm in Panama (PTY)

Layover in Panama for 11h 52m

Thu Mar 27th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$283

9:35am - 8:56am
Tue Mar 25th 2025

22h 21m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Tue Mar 25th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 14h 51m

Wed Mar 26th 2025 Copa Airlines · CM 837 Depart at 4:45am from Bogotá (BOG) Fly for 1h 51m Arrive at 6:36am in Panama (PTY)

Layover in Panama for 1h 10m

Wed Mar 26th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$285

4:47am - 8:13am
Tue Mar 25th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 407 Depart at 4:47am from Guatemala City (GUA) Fly for 2h 26m Arrive at 8:13am in Panama (PTY)
US$285

9:25pm - 10:25am
Wed Mar 26th 2025

12h 0m
Guatemala City (GUA) → Panama (PTY)

2 Stops

Wed Mar 26th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 6h 10m

Thu Mar 27th 2025 Avianca · AV 650 Depart at 5:05am from San José (SJO) Fly for 1h 20m Arrive at 6:25am in San Salvador (SAL)

Layover in San Salvador for 1h 5m

Thu Mar 27th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$286

10:23am - 1:49pm
Tue Mar 25th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)
US$286

1:12pm - 4:39pm
Wed Mar 26th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Wed Mar 26th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)
US$286

7:06am - 10:36am
Tue Mar 25th 2025

2h 30m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 389 Depart at 7:06am from Guatemala City (GUA) Fly for 2h 30m Arrive at 10:36am in Panama (PTY)
US$287

4:47am - 8:13am
Mon Mar 24th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 407 Depart at 4:47am from Guatemala City (GUA) Fly for 2h 26m Arrive at 8:13am in Panama (PTY)
US$287

10:23am - 1:49pm
Mon Mar 24th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)
US$298

10:30am - 8:00am
Tue Mar 25th 2025

20h 30m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Tue Mar 25th 2025 Avianca · AV 573 Depart at 10:30am from Guatemala City (GUA) Fly for 0h 50m Arrive at 11:20am in San Salvador (SAL)

Layover in San Salvador for 4h 45m

Tue Mar 25th 2025 Avianca · AV 131 Depart at 4:05pm from San Salvador (SAL) Fly for 2h 55m Arrive at 8:00pm in Bogotá (BOG)

Layover in Bogotá for 10h 15m

Wed Mar 26th 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)
US$300

7:06am - 10:36am
Mon Mar 24th 2025

2h 30m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 389 Depart at 7:06am from Guatemala City (GUA) Fly for 2h 30m Arrive at 10:36am in Panama (PTY)
US$302

9:35am - 8:00am
Mon Mar 24th 2025

21h 25m
Guatemala City (GUA) → Panama (BLB)

1 Stop

Mon Mar 24th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 16h 21m

Tue Mar 25th 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)
US$304

8:10pm - 8:00am
Tue Mar 25th 2025

10h 50m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Tue Mar 25th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 1h 5m

Tue Mar 25th 2025 Avianca · AV 365 Depart at 10:05pm from San Salvador (SAL) Fly for 2h 50m Arrive at 1:55am in Bogotá (BOG)

Layover in Bogotá for 4h 20m

Wed Mar 26th 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)
US$317

6:00am - 11:09am
Tue Mar 25th 2025

4h 9m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Tue Mar 25th 2025 Avianca · AV 655 Depart at 6:00am from Guatemala City (GUA) Fly for 1h 35m Arrive at 7:35am in San José (SJO)

Layover in San José for 1h 10m

Tue Mar 25th 2025 Copa Airlines · CM 763 Depart at 8:45am from San José (SJO) Fly for 1h 24m Arrive at 11:09am in Panama (PTY)
US$320

8:10pm - 8:09am
Wed Mar 26th 2025

10h 59m
Guatemala City (GUA) → Panama (PTY)

2 Stops

Wed Mar 26th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 1h 10m

Wed Mar 26th 2025 Avianca · AV 369 Depart at 10:10pm from San Salvador (SAL) Fly for 2h 45m Arrive at 1:55am in Medellín (MDE)

Layover in Medellín for 4h 45m

Thu Mar 27th 2025 Copa Airlines · CM 209 Depart at 6:40am from Medellín (MDE) Fly for 1h 29m Arrive at 8:09am in Panama (PTY)
US$324

5:20am - 10:25am
Mon Mar 24th 2025

4h 5m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 1h 20m

Mon Mar 24th 2025 Avianca · AV 323 Depart at 7:30am from San Salvador (SAL) Fly for 1h 55m Arrive at 10:25am in Panama (PTY)
US$324

5:20am - 2:45pm
Mon Mar 24th 2025

8h 25m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 5h 40m

Mon Mar 24th 2025 Avianca · AV 317 Depart at 11:50am from San Salvador (SAL) Fly for 1h 55m Arrive at 2:45pm in Panama (PTY)
US$326

9:35am - 7:58am
Mon Mar 24th 2025

21h 23m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Mon Mar 24th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 1h 31m

Mon Mar 24th 2025 Avianca · AV 9310 Depart at 3:25pm from Bogotá (BOG) Fly for 1h 6m Arrive at 4:31pm in Medellín (MDE)

Layover in Medellín for 14h 7m

Tue Mar 25th 2025 Wingo airlines · P5 7042 Depart at 6:38am from Medellín (MDE) Fly for 1h 20m Arrive at 7:58am in Panama (BLB)
US$336

10:30am - 8:56am
Tue Mar 25th 2025

21h 26m
Guatemala City (GUA) → David, Chiriquí (DAV)

3 Stops

Tue Mar 25th 2025 Avianca · AV 573 Depart at 10:30am from Guatemala City (GUA) Fly for 0h 50m Arrive at 11:20am in San Salvador (SAL)

Layover in San Salvador for 4h 45m

Tue Mar 25th 2025 Avianca · AV 131 Depart at 4:05pm from San Salvador (SAL) Fly for 2h 55m Arrive at 8:00pm in Bogotá (BOG)

Layover in Bogotá for 8h 45m

Wed Mar 26th 2025 Copa Airlines · CM 837 Depart at 4:45am from Bogotá (BOG) Fly for 1h 51m Arrive at 6:36am in Panama (PTY)

Layover in Panama for 1h 10m

Wed Mar 26th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$340

8:10pm - 5:22pm
Wed Mar 26th 2025

20h 12m
Guatemala City (GUA) → David, Chiriquí (DAV)

3 Stops

Wed Mar 26th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 1h 10m

Wed Mar 26th 2025 Avianca · AV 369 Depart at 10:10pm from San Salvador (SAL) Fly for 2h 45m Arrive at 1:55am in Medellín (MDE)

Layover in Medellín for 10h 4m

Thu Mar 27th 2025 Copa Airlines · CM 506 Depart at 11:59am from Medellín (MDE) Fly for 1h 29m Arrive at 1:28pm in Panama (PTY)

Layover in Panama for 2h 33m

Thu Mar 27th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$340

9:35am - 8:56am
Mon Mar 24th 2025

22h 21m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 743 Depart at 9:35am from Guatemala City (GUA) Fly for 3h 19m Arrive at 1:54pm in Bogotá (BOG)

Layover in Bogotá for 14h 56m

Tue Mar 25th 2025 Copa Airlines · CM 431 Depart at 4:50am from Bogotá (BOG) Fly for 1h 51m Arrive at 6:41am in Panama (PTY)

Layover in Panama for 1h 5m

Tue Mar 25th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$341

8:10pm - 8:56am
Tue Mar 25th 2025

11h 46m
Guatemala City (GUA) → David, Chiriquí (DAV)

3 Stops

Tue Mar 25th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 1h 5m

Tue Mar 25th 2025 Avianca · AV 365 Depart at 10:05pm from San Salvador (SAL) Fly for 2h 50m Arrive at 1:55am in Bogotá (BOG)

Layover in Bogotá for 2h 50m

Wed Mar 26th 2025 Copa Airlines · CM 837 Depart at 4:45am from Bogotá (BOG) Fly for 1h 51m Arrive at 6:36am in Panama (PTY)

Layover in Panama for 1h 10m

Wed Mar 26th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$344

9:25pm - 8:15am
Mon Mar 24th 2025

9h 50m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 6h 56m

Tue Mar 25th 2025 Copa Airlines · CM 465 Depart at 5:51am from San José (SJO) Fly for 1h 24m Arrive at 8:15am in Panama (PTY)
US$346

5:39am - 2:35pm
Tue Mar 25th 2025

7h 56m
Guatemala City (GUA) → Bocas Town, Bocas del Toro (BOC)

1 Stop

Tue Mar 25th 2025 Copa Airlines · CM 392 Depart at 5:39am from Guatemala City (GUA) Fly for 1h 42m Arrive at 7:21am in San José (SJO)

Layover in San José for 5h 9m

Tue Mar 25th 2025 WorldTicket · W1 3062 Depart at 12:30pm from San José (SJO) Fly for 1h 5m Arrive at 2:35pm in Bocas Town, Bocas del Toro (BOC)
US$348

5:20am - 11:41am
Mon Mar 24th 2025

5h 21m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 579 Depart at 5:20am from Guatemala City (GUA) Fly for 0h 50m Arrive at 6:10am in San Salvador (SAL)

Layover in San Salvador for 2h 20m

Mon Mar 24th 2025 Copa Airlines · CM 884 Depart at 8:30am from San Salvador (SAL) Fly for 2h 11m Arrive at 11:41am in Panama (PTY)
US$349

6:00am - 2:35pm
Tue Mar 25th 2025

7h 35m
Guatemala City (GUA) → Bocas Town, Bocas del Toro (BOC)

1 Stop

Tue Mar 25th 2025 Avianca · AV 655 Depart at 6:00am from Guatemala City (GUA) Fly for 1h 35m Arrive at 7:35am in San José (SJO)

Layover in San José for 4h 55m

Tue Mar 25th 2025 WorldTicket · W1 3062 Depart at 12:30pm from San José (SJO) Fly for 1h 5m Arrive at 2:35pm in Bocas Town, Bocas del Toro (BOC)
US$351

9:25pm - 2:35pm
Wed Mar 26th 2025

16h 10m
Guatemala City (GUA) → Bocas Town, Bocas del Toro (BOC)

1 Stop

Wed Mar 26th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 13h 35m

Thu Mar 27th 2025 Sansa Air · RZ 1062 Depart at 12:30pm from San José (SJO) Fly for 1h 5m Arrive at 2:35pm in Bocas Town, Bocas del Toro (BOC)
US$355

9:25pm - 4:22pm
Mon Mar 24th 2025

17h 57m
Guatemala City (GUA) → David, Chiriquí (DAV)

3 Stops

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 3h 20m

Tue Mar 25th 2025 Avianca · AV 693 Depart at 2:15am from San José (SJO) Fly for 2h 10m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 6h 43m

Tue Mar 25th 2025 Copa Airlines · CM 335 Depart at 12:08pm from Bogotá (BOG) Fly for 1h 46m Arrive at 1:54pm in Panama (PTY)

Layover in Panama for 1h 7m

Tue Mar 25th 2025 Copa Airlines · CM 26 Depart at 3:01pm from Panama (PTY) Fly for 1h 21m Arrive at 4:22pm in David, Chiriquí (DAV)
US$357

4:40pm - 8:00am
Mon Mar 24th 2025

14h 20m
Guatemala City (GUA) → Panama (BLB)

1 Stop

Mon Mar 24th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 9h 20m

Tue Mar 25th 2025 Wingo airlines · P5 7068 Depart at 6:15am from Bogotá (BOG) Fly for 1h 45m Arrive at 8:00am in Panama (BLB)
US$361

9:25pm - 5:22pm
Tue Mar 25th 2025

18h 57m
Guatemala City (GUA) → David, Chiriquí (DAV)

3 Stops

Tue Mar 25th 2025 Avianca · AV 641 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 3h 20m

Wed Mar 26th 2025 Avianca · AV 693 Depart at 2:15am from San José (SJO) Fly for 2h 10m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 6h 43m

Wed Mar 26th 2025 Copa Airlines · CM 335 Depart at 12:08pm from Bogotá (BOG) Fly for 1h 46m Arrive at 1:54pm in Panama (PTY)

Layover in Panama for 2h 7m

Wed Mar 26th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$374

3:45pm - 7:58am
Mon Mar 24th 2025

15h 13m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Mon Mar 24th 2025 Avianca · AV 555 Depart at 3:45pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 4:30pm in San Salvador (SAL)

Layover in San Salvador for 5h 40m

Mon Mar 24th 2025 Avianca · AV 369 Depart at 10:10pm from San Salvador (SAL) Fly for 2h 45m Arrive at 1:55am in Medellín (MDE)

Layover in Medellín for 4h 43m

Tue Mar 25th 2025 Wingo airlines · P5 7042 Depart at 6:38am from Medellín (MDE) Fly for 1h 20m Arrive at 7:58am in Panama (BLB)
US$379

9:25pm - 6:33am
Wed Mar 26th 2025

8h 8m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 5h 14m

Thu Mar 27th 2025 Copa Airlines · CM 461 Depart at 4:09am from San José (SJO) Fly for 1h 24m Arrive at 6:33am in Panama (PTY)
US$388

9:25pm - 12:31pm
Tue Mar 25th 2025

14h 6m
Guatemala City (GUA) → Panama (BLB)

3 Stops

Tue Mar 25th 2025 Avianca · AV 641 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 3h 20m

Wed Mar 26th 2025 Avianca · AV 693 Depart at 2:15am from San José (SJO) Fly for 2h 10m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 2h 4m

Wed Mar 26th 2025 Avianca · AV 8411 Depart at 7:29am from Bogotá (BOG) Fly for 1h 4m Arrive at 8:33am in Cali (CLO)

Layover in Cali for 2h 36m

Wed Mar 26th 2025 Wingo airlines · P5 7036 Depart at 11:09am from Cali (CLO) Fly for 1h 22m Arrive at 12:31pm in Panama (BLB)
US$395

4:40pm - 8:56am
Mon Mar 24th 2025

15h 16m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 7h 55m

Tue Mar 25th 2025 Copa Airlines · CM 431 Depart at 4:50am from Bogotá (BOG) Fly for 1h 51m Arrive at 6:41am in Panama (PTY)

Layover in Panama for 1h 5m

Tue Mar 25th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$397

3:45pm - 4:22pm
Mon Mar 24th 2025

23h 37m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 555 Depart at 3:45pm from Guatemala City (GUA) Fly for 0h 45m Arrive at 4:30pm in San Salvador (SAL)

Layover in San Salvador for 16h 0m

Tue Mar 25th 2025 Copa Airlines · CM 884 Depart at 8:30am from San Salvador (SAL) Fly for 2h 11m Arrive at 11:41am in Panama (PTY)

Layover in Panama for 3h 20m

Tue Mar 25th 2025 Copa Airlines · CM 26 Depart at 3:01pm from Panama (PTY) Fly for 1h 21m Arrive at 4:22pm in David, Chiriquí (DAV)
US$398

4:40pm - 7:58am
Mon Mar 24th 2025

14h 18m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Mon Mar 24th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 25m

Mon Mar 24th 2025 Avianca · AV 8449 Depart at 10:20pm from Bogotá (BOG) Fly for 1h 2m Arrive at 11:22pm in Medellín (MDE)

Layover in Medellín for 7h 16m

Tue Mar 25th 2025 Wingo airlines · P5 7042 Depart at 6:38am from Medellín (MDE) Fly for 1h 20m Arrive at 7:58am in Panama (BLB)
US$404

4:40pm - 5:22pm
Wed Mar 26th 2025

23h 42m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Wed Mar 26th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 15h 13m

Thu Mar 27th 2025 Copa Airlines · CM 335 Depart at 12:08pm from Bogotá (BOG) Fly for 1h 46m Arrive at 1:54pm in Panama (PTY)

Layover in Panama for 2h 7m

Thu Mar 27th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$409

4:40pm - 12:20am
Mon Mar 24th 2025

6h 40m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Mon Mar 24th 2025 Avianca · AV 40 Depart at 10:30pm from Bogotá (BOG) Fly for 1h 50m Arrive at 12:20am in Panama (PTY)
US$424

9:25pm - 3:16pm
Wed Mar 26th 2025

16h 51m
Guatemala City (GUA) → Panama (BLB)

3 Stops

Wed Mar 26th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 3h 20m

Thu Mar 27th 2025 Avianca · AV 693 Depart at 2:15am from San José (SJO) Fly for 2h 10m Arrive at 5:25am in Bogotá (BOG)

Layover in Bogotá for 5h 15m

Thu Mar 27th 2025 Avianca · AV 8533 Depart at 10:40am from Bogotá (BOG) Fly for 0h 58m Arrive at 11:38am in Medellín (MDE)

Layover in Medellín for 2h 18m

Thu Mar 27th 2025 Wingo airlines · P5 7046 Depart at 1:56pm from Medellín (MDE) Fly for 1h 20m Arrive at 3:16pm in Panama (BLB)
US$429

8:10pm - 7:58am
Mon Mar 24th 2025

10h 48m
Guatemala City (GUA) → Panama (BLB)

2 Stops

Mon Mar 24th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 1h 10m

Mon Mar 24th 2025 Avianca · AV 369 Depart at 10:10pm from San Salvador (SAL) Fly for 2h 45m Arrive at 1:55am in Medellín (MDE)

Layover in Medellín for 4h 43m

Tue Mar 25th 2025 Wingo airlines · P5 7042 Depart at 6:38am from Medellín (MDE) Fly for 1h 20m Arrive at 7:58am in Panama (BLB)
US$449

7:50am - 7:45pm
Mon Mar 24th 2025

10h 55m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 8h 1m

Mon Mar 24th 2025 Copa Airlines · CM 115 Depart at 5:21pm from San José (SJO) Fly for 1h 24m Arrive at 7:45pm in Panama (PTY)
US$449

7:50am - 8:30pm
Mon Mar 24th 2025

11h 40m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 8h 46m

Mon Mar 24th 2025 Copa Airlines · CM 839 Depart at 6:06pm from San José (SJO) Fly for 1h 24m Arrive at 8:30pm in Panama (PTY)
US$452

4:40pm - 8:56am
Wed Mar 26th 2025

15h 16m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Wed Mar 26th 2025 Avianca · AV 35 Depart at 4:40pm from Guatemala City (GUA) Fly for 3h 15m Arrive at 8:55pm in Bogotá (BOG)

Layover in Bogotá for 1h 35m

Wed Mar 26th 2025 Avianca · AV 40 Depart at 10:30pm from Bogotá (BOG) Fly for 1h 50m Arrive at 12:20am in Panama (PTY)

Layover in Panama for 7h 26m

Thu Mar 27th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$457

7:50am - 5:22pm
Mon Mar 24th 2025

8h 32m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 653 Depart at 7:50am from Guatemala City (GUA) Fly for 1h 30m Arrive at 9:20am in San José (SJO)

Layover in San José for 0h 55m

Mon Mar 24th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)

Layover in Panama for 3h 26m

Mon Mar 24th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$457

6:00am - 5:22pm
Wed Mar 26th 2025

10h 22m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Wed Mar 26th 2025 Avianca · AV 655 Depart at 6:00am from Guatemala City (GUA) Fly for 1h 35m Arrive at 7:35am in San José (SJO)

Layover in San José for 2h 40m

Wed Mar 26th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)

Layover in Panama for 3h 26m

Wed Mar 26th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$457

9:25pm - 4:22pm
Mon Mar 24th 2025

17h 57m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 11h 20m

Tue Mar 25th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)

Layover in Panama for 2h 26m

Tue Mar 25th 2025 Copa Airlines · CM 26 Depart at 3:01pm from Panama (PTY) Fly for 1h 21m Arrive at 4:22pm in David, Chiriquí (DAV)
US$457

9:25pm - 5:22pm
Mon Mar 24th 2025

18h 57m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 11h 20m

Tue Mar 25th 2025 Avianca · AV 643 Depart at 10:15am from San José (SJO) Fly for 1h 20m Arrive at 12:35pm in Panama (PTY)

Layover in Panama for 3h 26m

Tue Mar 25th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$476

10:23am - 5:22pm
Wed Mar 26th 2025

5h 59m
Guatemala City (GUA) → David, Chiriquí (DAV)

1 Stop

Wed Mar 26th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 2h 12m

Wed Mar 26th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$476

7:06am - 5:22pm
Mon Mar 24th 2025

9h 16m
Guatemala City (GUA) → David, Chiriquí (DAV)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 389 Depart at 7:06am from Guatemala City (GUA) Fly for 2h 30m Arrive at 10:36am in Panama (PTY)

Layover in Panama for 5h 25m

Mon Mar 24th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$476

4:47am - 5:22pm
Mon Mar 24th 2025

11h 35m
Guatemala City (GUA) → David, Chiriquí (DAV)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 407 Depart at 4:47am from Guatemala City (GUA) Fly for 2h 26m Arrive at 8:13am in Panama (PTY)

Layover in Panama for 7h 48m

Mon Mar 24th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$476

4:23pm - 8:56am
Mon Mar 24th 2025

15h 33m
Guatemala City (GUA) → David, Chiriquí (DAV)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 11h 56m

Tue Mar 25th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$476

4:23pm - 8:56am
Wed Mar 26th 2025

15h 33m
Guatemala City (GUA) → David, Chiriquí (DAV)

1 Stop

Wed Mar 26th 2025 Copa Airlines · CM 361 Depart at 4:23pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 7:50pm in Panama (PTY)

Layover in Panama for 11h 56m

Thu Mar 27th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$479

10:23am - 5:22pm
Mon Mar 24th 2025

5h 59m
Guatemala City (GUA) → David, Chiriquí (DAV)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)

Layover in Panama for 2h 12m

Mon Mar 24th 2025 Copa Airlines · CM 15 Depart at 4:01pm from Panama (PTY) Fly for 1h 21m Arrive at 5:22pm in David, Chiriquí (DAV)
US$520

4:47am - 8:13am
Tue Mar 25th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 407 Depart at 4:47am from Guatemala City (GUA) Fly for 2h 26m Arrive at 8:13am in Panama (PTY)
US$520

10:23am - 1:49pm
Tue Mar 25th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)
US$520

7:06am - 10:36am
Tue Mar 25th 2025

2h 30m
Guatemala City (GUA) → Panama (PTY)

Direct

Tue Mar 25th 2025 Copa Airlines · CM 389 Depart at 7:06am from Guatemala City (GUA) Fly for 2h 30m Arrive at 10:36am in Panama (PTY)
US$531

5:39am - 1:20pm
Mon Mar 24th 2025

6h 41m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 392 Depart at 5:39am from Guatemala City (GUA) Fly for 1h 42m Arrive at 7:21am in San José (SJO)

Layover in San José for 3h 35m

Mon Mar 24th 2025 Copa Airlines · CM 193 Depart at 10:56am from San José (SJO) Fly for 1h 24m Arrive at 1:20pm in Panama (PTY)
US$531

5:39am - 4:52pm
Mon Mar 24th 2025

10h 13m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 392 Depart at 5:39am from Guatemala City (GUA) Fly for 1h 42m Arrive at 7:21am in San José (SJO)

Layover in San José for 7h 7m

Mon Mar 24th 2025 Copa Airlines · CM 145 Depart at 2:28pm from San José (SJO) Fly for 1h 24m Arrive at 4:52pm in Panama (PTY)
US$531

5:39am - 5:30pm
Mon Mar 24th 2025

10h 51m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 392 Depart at 5:39am from Guatemala City (GUA) Fly for 1h 42m Arrive at 7:21am in San José (SJO)

Layover in San José for 7h 45m

Mon Mar 24th 2025 Copa Airlines · CM 343 Depart at 3:06pm from San José (SJO) Fly for 1h 24m Arrive at 5:30pm in Panama (PTY)
US$534

10:32am - 4:44pm
Mon Mar 24th 2025

5h 12m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Mon Mar 24th 2025 Copa Airlines · CM 380 Depart at 10:32am from Guatemala City (GUA) Fly for 1h 23m Arrive at 11:55am in Managua (MGA)

Layover in Managua for 2h 11m

Mon Mar 24th 2025 Copa Airlines · CM 105 Depart at 2:06pm from Managua (MGA) Fly for 1h 38m Arrive at 4:44pm in Panama (PTY)
US$534

10:32am - 4:44pm
Wed Mar 26th 2025

5h 12m
Guatemala City (GUA) → Panama (PTY)

1 Stop

Wed Mar 26th 2025 Copa Airlines · CM 380 Depart at 10:32am from Guatemala City (GUA) Fly for 1h 23m Arrive at 11:55am in Managua (MGA)

Layover in Managua for 2h 11m

Wed Mar 26th 2025 Copa Airlines · CM 105 Depart at 2:06pm from Managua (MGA) Fly for 1h 38m Arrive at 4:44pm in Panama (PTY)
US$534

10:23am - 1:49pm
Mon Mar 24th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 111 Depart at 10:23am from Guatemala City (GUA) Fly for 2h 26m Arrive at 1:49pm in Panama (PTY)
US$534

4:47am - 8:13am
Mon Mar 24th 2025

2h 26m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 407 Depart at 4:47am from Guatemala City (GUA) Fly for 2h 26m Arrive at 8:13am in Panama (PTY)
US$534

7:06am - 10:36am
Mon Mar 24th 2025

2h 30m
Guatemala City (GUA) → Panama (PTY)

Direct

Mon Mar 24th 2025 Copa Airlines · CM 389 Depart at 7:06am from Guatemala City (GUA) Fly for 2h 30m Arrive at 10:36am in Panama (PTY)
US$538

1:12pm - 4:39pm
Wed Mar 26th 2025

2h 27m
Guatemala City (GUA) → Panama (PTY)

Direct

Wed Mar 26th 2025 Copa Airlines · CM 384 Depart at 1:12pm from Guatemala City (GUA) Fly for 2h 27m Arrive at 4:39pm in Panama (PTY)
US$542

8:10pm - 8:56am
Mon Mar 24th 2025

35h 46m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 589 Depart at 8:10pm from Guatemala City (GUA) Fly for 0h 50m Arrive at 9:00pm in San Salvador (SAL)

Layover in San Salvador for 14h 50m

Tue Mar 25th 2025 Avianca · AV 317 Depart at 11:50am from San Salvador (SAL) Fly for 1h 55m Arrive at 2:45pm in Panama (PTY)

Layover in Panama for 17h 1m

Wed Mar 26th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$653

9:25pm - 8:56am
Mon Mar 24th 2025

34h 31m
Guatemala City (GUA) → David, Chiriquí (DAV)

2 Stops

Mon Mar 24th 2025 Avianca · AV 651 Depart at 9:25pm from Guatemala City (GUA) Fly for 1h 30m Arrive at 10:55pm in San José (SJO)

Layover in San José for 16h 11m

Tue Mar 25th 2025 Copa Airlines · CM 343 Depart at 3:06pm from San José (SJO) Fly for 1h 24m Arrive at 5:30pm in Panama (PTY)

Layover in Panama for 14h 16m

Wed Mar 26th 2025 Copa Airlines · CM 17 Depart at 7:46am from Panama (PTY) Fly for 1h 10m Arrive at 8:56am in David, Chiriquí (DAV)
US$3957

6:35pm - 4:50pm
Mon Mar 24th 2025

45h 15m
Guatemala City (GUA) → Panama (PTY)

2 Stops

Mon Mar 24th 2025 Iberia Airlines · IB 222 Depart at 6:35pm from Guatemala City (GUA) Fly for 1h 0m Arrive at 7:35pm in San Salvador (SAL)

Layover in San Salvador for 1h 30m

Mon Mar 24th 2025 Iberia Airlines · IB 222 Depart at 9:05pm from San Salvador (SAL) Fly for 10h 20m Arrive at 2:25pm in Madrid (MAD)

Layover in Madrid for 21h 20m

Wed Mar 26th 2025 Iberia Airlines · IB 257 Depart at 11:45am from Madrid (MAD) Fly for 11h 5m Arrive at 4:50pm in Panama (PTY)

Sarah Belizaire

@sarahbb1

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John Ford

@eyupitsjohn

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Roaming Sonaa

@roamingsonaa

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Andy Travels

@andy_travels

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Travel With Bender

@travelwitbender

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Wesley Mergard

@travel.with.wes

One useful tool I've found for evaluating different departure and return dates is called FlightList.io. You can quickly scan different travel date ranges, carriers and one way flight options to easily determine the cheapest flight combinations for your trip.

Flights from Guatemala City to Panama (GUA to PA)

Sarah Belizaire

John Ford

Roaming Sonaa

Andy Travels

Travel With Bender

Wesley Mergard

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